Literature DB >> 28238025

Anesthetic management of abdominal radical trachelectomy for uterine cervical cancer during pregnancy.

Jun Terukina1, Misako Takamatsu2, Takayuki Enomoto3, Hiroshi Baba4.   

Abstract

Abdominal radical trachelectomy has been identified as a surgical option for fertility preservation in cervical cancer patients, particularly in pregnant women who strongly desire to continue their pregnancy. Since this procedure requires operating in the uterus, the hardness of the uterus can affect the ease of surgery. Generally, sevoflurane is used for anesthesia in non-obstetric surgery for pregnant women because uterine relaxation is advantageous for uterine blood flow maintenance. However, the use of sevoflurane during radical trachelectomy has not been thoroughly evaluated. Here, we report on anesthesia use in three cases of abdominal radical trachelectomy during pregnancy. Propofol enabled maintenance of uterine tension while not significantly affecting fetal growth. It is important to consider maintenance of uterine tension and fetal circulation in anesthesia management. During the operation, we performed an ultrasound examination every 30 min to confirm fetal well-being. Although frequent fetal heart rate monitoring of the pre-viable fetus is not recommended, if fetal bradycardia is detected, sevoflurane may then be used to improve fetal circulation. Additionally, if the fetal heartbeat stops, a radical hysterectomy would then be required. Therefore, we consider that fetal heart rate monitoring during this procedure is necessary, and propofol is suitable as an anesthetic for this surgery during pregnancy.

Entities:  

Keywords:  Abdominal radical trachelectomy; Anesthesia; Pregnancy; Propofol

Mesh:

Substances:

Year:  2017        PMID: 28238025     DOI: 10.1007/s00540-017-2325-3

Source DB:  PubMed          Journal:  J Anesth        ISSN: 0913-8668            Impact factor:   2.078


  13 in total

1.  Radical trachelectomy in late pregnancy: is it an option?

Authors:  Ates Karateke; Cetin Cam; Cem Celik; Bahar Baykal; Niyazi Tug; Esra Ozbasli; Ozgur Aydin Tosun
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2010-06-18       Impact factor: 2.435

2.  Prolonged propofol infusions in pregnant neurosurgical patients.

Authors:  Gill Hilton; John Christopher Andrzejowski
Journal:  J Neurosurg Anesthesiol       Date:  2007-01       Impact factor: 3.956

3.  Comparison of the effects of sevoflurane and isoflurane anesthesia on the maternal-fetal unit in sheep.

Authors:  Toshiyuki Okutomi; Robert A Whittington; Deborah J Stein; Hisayo O Morishima
Journal:  J Anesth       Date:  2009-08-14       Impact factor: 2.078

4.  A successful case of abdominal radical trachelectomy for cervical cancer during pregnancy.

Authors:  Takayuki Enomoto; Kiyoshi Yoshino; Masami Fujita; Yukari Miyoshi; Yutaka Ueda; Shinsuke Koyama; Toshihiro Kimura; Takuji Tomimatsu; Tadashi Kimura
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2011-06-01       Impact factor: 2.435

5.  Abdominal radical trachelectomy during pregnancy to preserve pregnancy and fertility.

Authors:  László Ungár; J Richard Smith; László Pálfalvi; Giuseppe Del Priore
Journal:  Obstet Gynecol       Date:  2006-09       Impact factor: 7.661

6.  Radical abdominal trachelectomy for stage IB1 cervical cancer at 15-week gestation.

Authors:  Nadeem R Abu-Rustum; Moty N Tal; Deborah DeLair; Karin Shih; Yukio Sonoda
Journal:  Gynecol Oncol       Date:  2009-10-29       Impact factor: 5.482

7.  Propofol-induced apoptosis of neurones and oligodendrocytes in fetal and neonatal rhesus macaque brain.

Authors:  C Creeley; K Dikranian; G Dissen; L Martin; J Olney; A Brambrink
Journal:  Br J Anaesth       Date:  2013-06       Impact factor: 9.166

8.  The effect of propofol on isolated human pregnant uterine muscle.

Authors:  Y K Shin; Y D Kim; J V Collea
Journal:  Anesthesiology       Date:  1998-07       Impact factor: 7.892

Review 9.  Radical abdominal trachelectomy in the 19th gestation week in patients with early invasive cervical carcinoma: case study and overview of literature.

Authors:  Aljosa Mandic; Petar Novakovic; Dejan Nincic; Milica Zivaljevic; Jelka Rajovic
Journal:  Am J Obstet Gynecol       Date:  2009-06-13       Impact factor: 8.661

10.  Radical Abdominal Trachelectomy for IB1 Cervical Cancer at 17 Weeks of Gestation: A Case Report and Literature Review.

Authors:  Yoichi Aoki; Morihiko Inamine; Sugiko Ohishi; Yutaka Nagai; Hitoshi Masamoto
Journal:  Case Rep Obstet Gynecol       Date:  2014-12-08
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  1 in total

1.  The Safety and Effectiveness of Abdominal Radical Trachelectomy for Early-Stage Cervical Cancer During Pregnancy.

Authors:  Kosuke Yoshihara; Tatsuya Ishiguro; Makoto Chihara; Eiri Shima; Sosuke Adachi; Masanori Isobe; Kazufumi Haino; Masayuki Yamaguchi; Masayuki Sekine; Katsunori Kashima; Koichi Takakuwa; Nobumichi Nishikawa; Takayuki Enomoto
Journal:  Int J Gynecol Cancer       Date:  2018-05       Impact factor: 3.437

  1 in total

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