Literature DB >> 28237947

Hypercalcaemia caused by active pulmonary tuberculosis in an elderly person without fever or pulmonary symptoms.

Shogo Hanai1, Takashi Shinzato2, Daiki Inazu2, Yasuharu Tokuda3.   

Abstract

Many diseases can cause hypercalcaemia, including primary hyperparathyroidism, cancer, drugs and granulomatous diseases. A nursing home resident aged 81 years was admitted because of altered mental status. The patient did not have fever, cough, sputum or night sweat. Hypercalcaemia was identified as a cause of the consciousness disturbance. Chest radiograph showed no acute process. Laboratory workups revealed elevated serum levels of 1,25-(OH)2 vitamin D3 and positive T-spot test. Microscopic examination of the suctioned sputum identified acid-fast bacilli, which was confirmed as Mycobactrium tuberculsosis Tuberculosis should be considered as the important cause of hypercalcaemia since early diagnosis and treatment is recommended for preventing its outbreak among people with close contacts with patients. 2017 BMJ Publishing Group Ltd.

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Year:  2017        PMID: 28237947      PMCID: PMC5337663          DOI: 10.1136/bcr-2016-217797

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  5 in total

1.  The causes of hypercalcemia in Okinawan patients: an international comparison.

Authors:  Yasuharu Tokuda; Kyouko Maezato; Gerald H Stein
Journal:  Intern Med       Date:  2007-01-01       Impact factor: 1.271

2.  Differences in vitamin D status and calcium intake: possible explanations for the regional variations in the prevalence of hypercalcemia in tuberculosis.

Authors:  T Y Chan
Journal:  Calcif Tissue Int       Date:  1997-01       Impact factor: 4.333

3.  Incidence, causes and mechanism of hypercalcaemia in a hospital population in Hong Kong.

Authors:  C C Shek; A Natkunam; V Tsang; C S Cockram; R Swaminathan
Journal:  Q J Med       Date:  1990-12

4.  Low incidence of hypercalcaemia in tuberculosis in Malaysia.

Authors:  T T Tan; B C Lee; B A Khalid
Journal:  J Trop Med Hyg       Date:  1993-12

5.  Vitamin D metabolism in tuberculosis. Production of 1,25(OH)2D3 by cells recovered by bronchoalveolar lavage and the role of this metabolite in calcium homeostasis.

Authors:  J Cadranel; A J Hance; B Milleron; F Paillard; G M Akoun; M Garabedian
Journal:  Am Rev Respir Dis       Date:  1988-10
  5 in total
  2 in total

1.  Hypercalcemia caused by comorbid parathyroid adenoma and pulmonary tuberculosis.

Authors:  Sahoko Kamejima; Izumi Yamamoto; Arisa Kobayashi; Akio Nakashima; Taketo Uchiyama; Ichiro Ohkido; Takashi Yokoo
Journal:  CEN Case Rep       Date:  2020-07-06

2.  Malignant melanoma with indiscoverable skin manifestations presenting with paresis and refractory hypercalcemia: A case report.

Authors:  Pei-Pei Wang; Xi Zhou; Xi Chen; Li-Wen Wang; Yong Liu
Journal:  Medicine (Baltimore)       Date:  2019-02       Impact factor: 1.817

  2 in total

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