| Literature DB >> 28237418 |
Dustin Ameis1, Naghmeh Khoshgoo1, Barbara M Iwasiow1, Phillip Snarr1, Richard Keijzer2.
Abstract
MicroRNAs (miRNAs) are small (∼22 nucleotides), non-coding RNA molecules that regulate gene expression post-transcriptionally by inhibiting target mRNAs. Research into the roles of miRNAs in lung development and disease is at the early stages. In this review, we discuss the role of miRNAs in pediatric respiratory disease, including cystic fibrosis, asthma, and bronchopulmonary dysplasia.Entities:
Keywords: MicroRNAs; asthma; bronchopulmonary dysplasia; cystic fibrosis; gene expression; lung development
Mesh:
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Year: 2016 PMID: 28237418 DOI: 10.1016/j.prrv.2016.12.002
Source DB: PubMed Journal: Paediatr Respir Rev ISSN: 1526-0542 Impact factor: 2.726