Anne Elisabeth Chaumet-Riffaud1, Philippe Chaumet-Riffaud2, Anaelle Cariou3, Céline Devisme3, Isabelle Audo4, José-Alain Sahel5, Saddek Mohand-Said4. 1. CHNO des Quinze-Vingts, DHU Sight Restore, INSERM-DGOS CIC 1423, Paris, France. Electronic address: aecr1520@gmail.com. 2. Service de Biophysique et Médecine nucléaire, Hôpitaux universitaires Paris Sud, Bicêtre APHP Univ Paris Sud, Le Kremlin Bicêtre, France. 3. CHNO des Quinze-Vingts, DHU Sight Restore, INSERM-DGOS CIC 1423, Paris, France. 4. CHNO des Quinze-Vingts, DHU Sight Restore, INSERM-DGOS CIC 1423, Paris, France; Sorbonne Universités, UPMC Univ Paris 06 UMR S968, INSERM U 968, CNRS, UMR_7210, Institut de la Vision, Paris, France. 5. CHNO des Quinze-Vingts, DHU Sight Restore, INSERM-DGOS CIC 1423, Paris, France; Sorbonne Universités, UPMC Univ Paris 06 UMR S968, INSERM U 968, CNRS, UMR_7210, Institut de la Vision, Paris, France; Fondation Ophtalmologique Adolphe de Rothschild Hospital, Paris, France; Department of Ophthalmology, The University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Abstract
PURPOSE: To determine the relationship between visual function and quality of life, education, mental health, and employment among young adults with retinitis pigmentosa (RP). DESIGN: Cross-sectional study. METHODS: Inclusion of 148 patients (mean age 38.2 ± 7.1 years) diagnosed with RP, living in France. Quality of life was assessed using the National Eye Institute Visual Function Questionnaire (VFQ-25), mental state with the Hospital and Anxiety and Depression Scale (HADS), and employment with a specifically designed questionnaire. RESULTS: Limited visual impairment was noted in 22.3%, low vision in 29.7%, and legal blindness in 48.0%. There was a correlation between quality-of-life scores and residual visual field (P < .0001). Mental health scores were suggestive of anxiety in 36.5% and depression in 15.5%. The rates did not increase with disability level (P = .738, P = .134). The percentage of subjects with higher education did not significantly decrease with disability level (P = .113). The employment rate did not significantly decrease with disability level (P = .276). It was lower in subjects reporting depression (P = .0414). Self-rated impact of RP on employment increased with disability level (P = .02642). CONCLUSIONS: Our results differ from previous results showing lower education rates and employment rates in young adults with RP. Further research is warranted focusing on the impact of mental health, education, workplace conditions, and employment aids on employment rate vs age- and education-matched normally sighted controls to guide visual disability strategies in RP.
PURPOSE: To determine the relationship between visual function and quality of life, education, mental health, and employment among young adults with retinitis pigmentosa (RP). DESIGN: Cross-sectional study. METHODS: Inclusion of 148 patients (mean age 38.2 ± 7.1 years) diagnosed with RP, living in France. Quality of life was assessed using the National Eye Institute Visual Function Questionnaire (VFQ-25), mental state with the Hospital and Anxiety and Depression Scale (HADS), and employment with a specifically designed questionnaire. RESULTS: Limited visual impairment was noted in 22.3%, low vision in 29.7%, and legal blindness in 48.0%. There was a correlation between quality-of-life scores and residual visual field (P < .0001). Mental health scores were suggestive of anxiety in 36.5% and depression in 15.5%. The rates did not increase with disability level (P = .738, P = .134). The percentage of subjects with higher education did not significantly decrease with disability level (P = .113). The employment rate did not significantly decrease with disability level (P = .276). It was lower in subjects reporting depression (P = .0414). Self-rated impact of RP on employment increased with disability level (P = .02642). CONCLUSIONS: Our results differ from previous results showing lower education rates and employment rates in young adults with RP. Further research is warranted focusing on the impact of mental health, education, workplace conditions, and employment aids on employment rate vs age- and education-matched normally sighted controls to guide visual disability strategies in RP.
Authors: Gabrielle D Lacy; Maria Fernanda Abalem; Lilia T Popova; Erin P Santos; Gina Yu; Hanan Y Rakine; Julie M Rosenthal; Joshua R Ehrlich; David C Musch; K Thiran Jayasundera Journal: Ophthalmic Genet Date: 2020-06-22 Impact factor: 1.803
Authors: Xuan-Thanh-An Nguyen; Jan Koopman; Maria M van Genderen; Henk L M Stam; Camiel J F Boon Journal: Acta Ophthalmol Date: 2021-09-26 Impact factor: 3.988
Authors: Gabrielle D Lacy; Maria Fernanda Abalem; Chris A Andrews; Rebhi Abuzaitoun; Lilia T Popova; Erin P Santos; Gina Yu; Hanan Y Rakine; Natasha Baig; Joshua R Ehrlich; Abigail T Fahim; Kari H Branham; Bonnielin K Swenor; Paul R Lichter; Gislin Dagnelie; Joan A Stelmack; David C Musch; K Thiran Jayasundera Journal: Am J Ophthalmol Date: 2020-12-09 Impact factor: 5.258
Authors: Jacque L Duncan; Wendi Liang; Maureen G Maguire; Isabelle Audo; Allison R Ayala; David G Birch; Joseph Carroll; Janet K Cheetham; Simona Degli Esposti; Todd A Durham; Laura Erker; Sina Farsiu; Frederick L Ferris; Elise Heon; Robert B Hufnagel; Alessandro Iannaccone; Glenn J Jaffe; Christine N Kay; Michel Michaelides; Mark E Pennesi; José-Alain Sahel Journal: Am J Ophthalmol Date: 2020-05-22 Impact factor: 5.488
Authors: Francisco M Costela; Konrad Pesudovs; Michael A Sandberg; Carol Weigel-DiFranco; Russell L Woods Journal: Health Qual Life Outcomes Date: 2020-06-22 Impact factor: 3.186
Authors: John R Grigg; Claire Y Hooper; Clare L Fraser; Elisa E Cornish; Peter J McCluskey; Robyn V Jamieson Journal: Eye (Lond) Date: 2020-04-20 Impact factor: 3.775