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Literature DB >> 2823678

The malignant potential of colorectal Crohn's disease.

M G Wyatt¹, P W Houghton, N J Mortensen, R C Williamson.

Abstract

Six patients developed colorectal carcinoma in association with Crohn's disease. The cancer was diagnosed at a mean age of 46 years and a mean 19 years after the onset of Crohn's disease. Five carcinomas arose in the chronically inflamed segment of bowel, while a sixth arose in caecum previously bypassed for Crohn's ileitis. Four carcinomas were mucinous, four presented with fistula and four were treated by complete removal of the large intestine. Three patients have died of residual or recurrent cancer. The data support an aetiological link between Crohn's proctocolitis and carcinoma.

Entities: Disease Species

Mesh：

Year: 1987 PMID： 2823678 PMCID： PMC2498584

Source DB: PubMed Journal: Ann R Coll Surg Engl ISSN： 0035-8843 Impact factor: 1.891

20 in total

6. Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: implications for carcinogenesis and prevention.

Authors: P M Choi; M P Zelig
Journal: Gut Date: 1994-07 Impact factor: 23.059

6 in total

The malignant potential of colorectal Crohn's disease.

1. Multifocal colonic carcinoma and Crohn's disease.

2. Cicatrizing enteritis as a pathologic entity; analysis of 120 cases.

3. The risk of cancer in Crohn's disease.

4. Carcinoma of the anus in Crohn's disease.

5. Cancer in Crohn's disease after diversionary surgery. A report of seven carcinomas occurring in excluded bowel.

6. The histologic appearance of dysplasia (precarcinomatous change) in Crohn's disease of the small and large intestine.

7. Patterns of neoplasia in Crohn's disease and ulcerative colitis.

8. Peculiarities of mucinous colorectal carcinoma.

9. A comparison of cancer risk in Crohn's disease and ulcerative colitis.

10. Survival of 727 patients with single carcinomas of the large bowel.

Review 1. Cancer in inflammatory bowel disease.

2. Noninvasive detection of inflammation-associated colon cancer in a mouse model.

3. [Contraction of the hip and fecal drainage via a fistula tract 30 years after "appendectomy"].

4. Two types of colorectal carcinoma in Crohn's disease.

Review 5. Malignant transformation in perianal fistulas of Crohn's disease: a systematic review of literature.

6. Similarity of colorectal cancer in Crohn's disease and ulcerative colitis: implications for carcinogenesis and prevention.