Ruth C Shinnar1, Shlomo Shinnar2, Dale C Hesdorffer3, Kathryn O'Hara4, Terrie Conklin5, Karen Mohler Cornett6, Diana Miazga7, Shumei Sun8. 1. Neurology and Pediatrics, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA. Electronic address: codell@sprynet.com. 2. Neurology and Pediatrics, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA. 3. GH Sergievsky Center, and Department of Epidemiology, Columbia University, New York, NY 10032, USA. 4. Pediatric Neurology, Virginia Commonwealth University, Richmond, VA 23298, USA. 5. Neurology, Children's Hospital of The King's Daughter, Norfolk, VA 23507, USA. 6. Duke University Medical Center, Durham, NC 27710, USA. 7. Neurology, Lurie Children's Hospital, Chicago, IL 60611, USA. 8. Department of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298, USA.
Abstract
Febrile status epilepticus is a serious and frightening event in the life of the child and parent. It is regarded as a medical emergency with potential long lasting consequences. The purpose of this study was to look at the immediate and long term effects of such an event on parental stress and parents' perception of their child's physical and psychosocial wellbeing. METHODS: From 2003 to 2010, 199 subjects, age 1 month to 5 years, were recruited as part of a prospective, multicenter study (FEBSTAT) of consequences of febrile status epilepticus (FSE). At one month and one year after the episode of FSE, parents were asked to complete the Parenting Stress Index, short form (PSI/SF), the Pediatric Quality of Life Inventory (PedsQL) and the Child Behavior Checklist (CBCL). In addition to PedsQL and CBCL in the FEBSTAT subjects only, a comparison was made between Columbia Study of First Febrile Seizures subjects with a first simple febrile seizure (SFS) and the FEBSTAT group, including 15 subjects with FSE from the Columbia group, in the area of parental stress which was administered at the same time intervals in both studies. RESULTS: At baseline, the PSI/SF was statistically significantly higher for SFS versus FSE on the parent-child dysfunctional score and the total raw score, however at one year this difference resolved. In the FSE group, significantly higher parental stress over one year was reported in children with abnormal versus normal prior development (p= 0.02). Prior abnormal development was a risk factor at 1 year for lower total PEDSQL (p=0.01) versus prior normal development. Mean scores on the CBCL at baseline and 1 year were within the normal range for both empirically based scales and major risk factors. CONCLUSIONS: Parents of children experiencing a SFS experienced more stress at baseline than those with FSE. Families of children in the FEBSTAT cohort with identified development problems at baseline that continued, or progressed over the one year period, reported decreasing QOL.
Febrile status epilepticus is a serious and frightening event in the life of the child and parent. It is regarded as a medical emergency with potential long lasting consequences. The purpose of this study was to look at the immediate and long term effects of such an event on parental stress and parents' perception of their child's physical and psychosocial wellbeing. METHODS: From 2003 to 2010, 199 subjects, age 1 month to 5 years, were recruited as part of a prospective, multicenter study (FEBSTAT) of consequences of febrile status epilepticus (FSE). At one month and one year after the episode of FSE, parents were asked to complete the Parenting Stress Index, short form (PSI/SF), the Pediatric Quality of Life Inventory (PedsQL) and the Child Behavior Checklist (CBCL). In addition to PedsQL and CBCL in the FEBSTAT subjects only, a comparison was made between Columbia Study of First Febrile Seizures subjects with a first simple febrile seizure (SFS) and the FEBSTAT group, including 15 subjects with FSE from the Columbia group, in the area of parental stress which was administered at the same time intervals in both studies. RESULTS: At baseline, the PSI/SF was statistically significantly higher for SFS versus FSE on the parent-child dysfunctional score and the total raw score, however at one year this difference resolved. In the FSE group, significantly higher parental stress over one year was reported in children with abnormal versus normal prior development (p= 0.02). Prior abnormal development was a risk factor at 1 year for lower total PEDSQL (p=0.01) versus prior normal development. Mean scores on the CBCL at baseline and 1 year were within the normal range for both empirically based scales and major risk factors. CONCLUSIONS: Parents of children experiencing a SFS experienced more stress at baseline than those with FSE. Families of children in the FEBSTAT cohort with identified development problems at baseline that continued, or progressed over the one year period, reported decreasing QOL.
Authors: Nicholas S Abend; Katherine L Wagenman; Taylor P Blake; Maria T Schultheis; Jerilynn Radcliffe; Robert A Berg; Alexis A Topjian; Dennis J Dlugos Journal: Epilepsy Behav Date: 2015-04-20 Impact factor: 2.937
Authors: David J Thurman; Ettore Beghi; Charles E Begley; Anne T Berg; Jeffrey R Buchhalter; Ding Ding; Dale C Hesdorffer; W Allen Hauser; Lewis Kazis; Rosemarie Kobau; Barbara Kroner; David Labiner; Kore Liow; Giancarlo Logroscino; Marco T Medina; Charles R Newton; Karen Parko; Angelia Paschal; Pierre-Marie Preux; Josemir W Sander; Anbesaw Selassie; William Theodore; Torbjörn Tomson; Samuel Wiebe Journal: Epilepsia Date: 2011-09 Impact factor: 5.864
Authors: David W Loring; Daniel H Lowenstein; Nicholas M Barbaro; Brandy E Fureman; Joanne Odenkirchen; Margaret P Jacobs; Joan K Austin; Dennis J Dlugos; Jacqueline A French; William Davis Gaillard; Bruce P Hermann; Dale C Hesdorffer; Steven N Roper; Anne C Van Cott; Stacie Grinnon; Alexandra Stout Journal: Epilepsia Date: 2011-03-22 Impact factor: 5.864
Authors: Dale C Hesdorffer; Shlomo Shinnar; Darrell V Lewis; Solomon L Moshé; Douglas R Nordli; John M Pellock; James MacFall; Ruth C Shinnar; David Masur; L Matthew Frank; Leon G Epstein; Claire Litherland; Syndi Seinfeld; Jacqueline A Bello; Stephen Chan; Emilia Bagiella; Shumei Sun Journal: Epilepsia Date: 2012-06-28 Impact factor: 5.864
Authors: Eugen Trinka; Hannah Cock; Dale Hesdorffer; Andrea O Rossetti; Ingrid E Scheffer; Shlomo Shinnar; Simon Shorvon; Daniel H Lowenstein Journal: Epilepsia Date: 2015-09-04 Impact factor: 5.864
Authors: Shanil Ebrahim; Simran Singh; Jamie S Hutchison; Abhaya V Kulkarni; Renee Sananes; Kerry W Bowman; Christopher S Parshuram Journal: Pediatr Crit Care Med Date: 2013-01 Impact factor: 3.624