Literature DB >> 28235647

Pediatric Trauma Assessment and Management Database: Leveraging Existing Data Systems to Predict Mortality and Functional Status after Pediatric Injury.

Katherine T Flynn-O'Brien1, Mary E Fallat2, Tom B Rice3, Christine M Gall4, Michael L Nance5, Jeffrey S Upperman6, David M Gourlay7, John P Crow8, Frederick P Rivara9.   

Abstract

BACKGROUND: Efforts to improve pediatric trauma outcomes need detailed data, optimally collected at lowest cost, to assess processes of care. We developed a novel database by merging 2 national data systems for 5 pediatric trauma centers to provide benchmarking metrics for mortality and non-mortality outcomes and to assess care provided throughout the care continuum. STUDY
DESIGN: Trauma registry and Virtual Pediatric Systems, LLC (VPS) from 5 pediatric trauma centers were merged for children younger than 18 years discharged in 2013 from a pediatric ICU after traumatic injury. For inpatient mortality, we compared risk-adjusted models for trauma registry only, VPS only, and a combination of trauma registry and VPS variables (trauma registry+VPS). To estimate risk-adjusted functional status, we created a prediction model de novo through purposeful covariate selection using dichotomized Pediatric Overall Performance Category scale.
RESULTS: Of 688 children included, 77.3% were discharged from the ICU with good performance or mild overall disability and 17.6% with moderate or severe overall disability or coma. Inpatient mortality was 5.1%. The combined dataset provided the best-performing risk-adjusted model for predicting mortality, as measured by the C-statistic, pseudo-R2, and Akaike Information Criterion, when compared with the trauma registry-only model. The final Pediatric Overall Performance Category model demonstrated adequate discrimination (C-statistic = 0.896) and calibration (Hosmer-Lemeshow goodness-of-fit p = 0.65). The probability of poor outcomes varied significantly by site (p < 0.0001).
CONCLUSIONS: Merging 2 data systems allowed for improved risk-adjusted modeling for mortality and functional status. The merged database allowed for patient evaluation throughout the care continuum on a multi-institutional level. Merging existing data is feasible, innovative, and has potential to impact care with minimal new resources.
Copyright © 2017 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

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Mesh:

Year:  2017        PMID: 28235647      PMCID: PMC6475528          DOI: 10.1016/j.jamcollsurg.2017.01.061

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  25 in total

1.  The comparative assessment and improvement of quality of surgical care in the Department of Veterans Affairs.

Authors:  Shukri F Khuri; Jennifer Daley; William G Henderson
Journal:  Arch Surg       Date:  2002-01

2.  Theoretical and empirical derivation of cardiovascular allometric relationships in children.

Authors:  Thierry Sluysmans; Steven D Colan
Journal:  J Appl Physiol (1985)       Date:  2004-11-19

3.  Choosing outcome assessment instruments for trauma registries.

Authors:  Belinda J Gabbe; Owen D Williamson; Peter A Cameron; Adam S Dowrick
Journal:  Acad Emerg Med       Date:  2005-08       Impact factor: 3.451

4.  A randomized trial of very early decompressive craniectomy in children with traumatic brain injury and sustained intracranial hypertension.

Authors:  A Taylor; W Butt; J Rosenfeld; F Shann; M Ditchfield; E Lewis; G Klug; D Wallace; R Henning; J Tibballs
Journal:  Childs Nerv Syst       Date:  2001-02       Impact factor: 1.475

5.  Relationship of illness severity and length of stay to functional outcomes in the pediatric intensive care unit: a multi-institutional study.

Authors:  D H Fiser; J M Tilford; P K Roberson
Journal:  Crit Care Med       Date:  2000-04       Impact factor: 7.598

6.  Relationship of pediatric overall performance category and pediatric cerebral performance category scores at pediatric intensive care unit discharge with outcome measures collected at hospital discharge and 1- and 6-month follow-up assessments.

Authors:  D H Fiser; N Long; P K Roberson; G Hefley; K Zolten; M Brodie-Fowler
Journal:  Crit Care Med       Date:  2000-07       Impact factor: 7.598

7.  Improved functional outcome for severely injured children treated at pediatric trauma centers.

Authors:  D A Potoka; L C Schall; H R Ford
Journal:  J Trauma       Date:  2001-11

8.  The worst injury predicts mortality outcome the best: rethinking the role of multiple injuries in trauma outcome scoring.

Authors:  Patrick D Kilgo; Turner M Osler; Wayne Meredith
Journal:  J Trauma       Date:  2003-10

9.  Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study.

Authors:  Stéphane Leteurtre; Alain Martinot; Alain Duhamel; François Proulx; Bruno Grandbastien; Jacques Cotting; Ronald Gottesman; Ari Joffe; Jurg Pfenninger; Philippe Hubert; Jacques Lacroix; Francis Leclerc
Journal:  Lancet       Date:  2003-07-19       Impact factor: 79.321

10.  PIM2: a revised version of the Paediatric Index of Mortality.

Authors:  Anthony Slater; Frank Shann; Gale Pearson
Journal:  Intensive Care Med       Date:  2003-01-23       Impact factor: 17.440

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