Literature DB >> 28235591

Folate-mediated chemotherapy and diagnostics: An updated review and outlook.

Leyuan Xu1, Qianming Bai2, Xin Zhang3, Hu Yang4.   

Abstract

Folate receptor (FR) is highly expressed in many types of human cancers, and it has been actively studied for developing targeted chemotherapy and diagnostic agents. Tremendous efforts have been made in developing FR-targeted nanomedicines and nanoprobes and translating them into clinical applications. This article provides a concise review on the latest development of folate-mediated nanomedicines and nanoprobes for chemotherapy and diagnostics with an emphasis on in vivo applications. The cellular uptake mechanisms, pharmacokinetics (PK), administration routes and major challenges in FR-targeted nanoparticles are discussed.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Diagnosis; Folate receptor; Folic acid; Nanomedicine; Targeted delivery

Mesh：

Substances：

Year:  2017        PMID： 28235591      PMCID： PMC5479736          DOI： 10.1016/j.jconrel.2017.02.023

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  90 in total

1.  Overexpression of folate binding protein in ovarian cancers.

Authors:  G Toffoli; C Cernigoi; A Russo; A Gallo; M Bagnoli; M Boiocchi
Journal:  Int J Cancer       Date:  1997-04-22       Impact factor: 7.396

Review 2.  Image-driven pharmacokinetics: nanomedicine concentration across space and time.

Authors:  Dab A Brill; J Andrew MacKay
Journal:  Nanomedicine (Lond)       Date:  2015-09-15       Impact factor: 5.307

3.  A high-affinity folate binding protein in proximal tubule cells of human kidney.

Authors:  J Holm; S I Hansen; M Høier-Madsen; L Bostad
Journal:  Kidney Int       Date:  1992-01       Impact factor: 10.612

4.  A Multi-Functional Tumor Theranostic Nanoplatform for MRI Guided Photothermal-Chemotherapy.

Authors:  Jinjin Shi; Binghua Wang; Zhaoyang Chen; Wei Liu; Jingjing Pan; Lin Hou; Zhenzhong Zhang
Journal:  Pharm Res       Date:  2016-03-16       Impact factor: 4.200

Review 5.  Folate and carcinogenesis: an integrated scheme.

Authors:  S W Choi; J B Mason
Journal:  J Nutr       Date:  2000-02       Impact factor: 4.798

Review 6.  Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats.

Authors:  Michelle Longmire; Peter L Choyke; Hisataka Kobayashi
Journal:  Nanomedicine (Lond)       Date:  2008-10       Impact factor: 5.307

7.  PEI-derivatized fullerene drug delivery using folate as a homing device targeting to tumor.

Authors:  Jinjin Shi; Hongling Zhang; Lei Wang; Lulu Li; Honghong Wang; Zhenzhen Wang; Zhi Li; Chengqun Chen; Lin Hou; Chaofeng Zhang; Zhenzhong Zhang
Journal:  Biomaterials       Date:  2012-10-13       Impact factor: 12.479

8.  Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time.

Authors:  Andrea B Kramer; Mirjan M van Timmeren; Theo A Schuurs; Vishal S Vaidya; Joseph V Bonventre; Harry van Goor; Gerjan Navis
Journal:  Am J Physiol Renal Physiol       Date:  2009-02-18

9.  Three-Dimensional Morphology by Multiphoton Microscopy with Clearing in a Model of Cisplatin-Induced CKD.

Authors:  Richard Torres; Heino Velazquez; John J Chang; Michael J Levene; Gilbert Moeckel; Gary V Desir; Robert Safirstein
Journal:  J Am Soc Nephrol       Date:  2015-08-24       Impact factor: 10.121

10.  Photosensitizer enhanced disassembly of amphiphilic micelle for ROS-response targeted tumor therapy in vivo.

Authors:  Liangliang Dai; Yonglin Yu; Zhong Luo; Menghuan Li; Weizhen Chen; Xinkun Shen; Feng Chen; Qiang Sun; Qingfeng Zhang; Hao Gu; Kaiyong Cai
Journal:  Biomaterials       Date:  2016-07-05       Impact factor: 12.479
View more
  12 in total

1.  PET/NIR-II fluorescence imaging and image-guided surgery of glioblastoma using a folate receptor α-targeted dual-modal nanoprobe.

Authors:  Xiaojing Shi; Pengfei Xu; Caiguang Cao; Zhen Cheng; Jie Tian; Zhenhua Hu
Journal:  Eur J Nucl Med Mol Imaging       Date:  2022-07-15       Impact factor: 10.057

2.  Folic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: Its utility for local siRNA delivery.

Authors:  Leyuan Xu; W Andrew Yeudall; Hu Yang
Journal:  Acta Biomater       Date:  2017-04-22       Impact factor: 8.947

3.  Delivery luteolin with folacin-modified nanoparticle for glioma therapy.

Authors:  Cong Wu; Qian Xu; Xinyue Chen; Jiagang Liu
Journal:  Int J Nanomedicine       Date:  2019-09-16

4.  Dual Receptor-Targeted and Redox-Sensitive Polymeric Micelles Self-Assembled from a Folic Acid-Hyaluronic Acid-SS-Vitamin E Succinate Polymer for Precise Cancer Therapy.

Authors:  Yue Yang; Yunjian Li; Kai Chen; Ling Zhang; Sen Qiao; Guoxin Tan; Fen Chen; Weisan Pan
Journal:  Int J Nanomedicine       Date:  2020-04-24

5.  Identification of a PET Radiotracer for Imaging of the Folate Receptor-α: A Potential Tool to Select Patients for Targeted Tumor Therapy.

Authors:  Patrycja Guzik; Hsin-Yu Fang; Luisa M Deberle; Martina Benešová; Susan Cohrs; Silvan D Boss; Simon M Ametamey; Roger Schibli; Cristina Müller
Journal:  J Nucl Med       Date:  2021-01-15       Impact factor: 10.057

6.  Thermally-responsive Virus-like Particle for Targeted Delivery of Cancer Drug.

Authors:  Qiu Xian Thong; Roya Biabanikhankahdani; Kok Lian Ho; Noorjahan Banu Alitheen; Wen Siang Tan
Journal:  Sci Rep       Date:  2019-03-08       Impact factor: 4.379

7.  Combination Treatment of Cervical Cancer Using Folate-Decorated, pH-Sensitive, Carboplatin and Paclitaxel Co-Loaded Lipid-Polymer Hybrid Nanoparticles.

Authors:  Junjian Wang
Journal:  Drug Des Devel Ther       Date:  2020-02-26       Impact factor: 4.162

8.  Biocompatible nucleus-targeted graphene quantum dots for selective killing of cancer cells via DNA damage.

Authors:  Lei Qi; Tonghe Pan; Liling Ou; Zhiqiang Ye; Chunlei Yu; Bijun Bao; Zixia Wu; Dayong Cao; Liming Dai
Journal:  Commun Biol       Date:  2021-02-16

9.  Effect of inhibitors of endocytosis and NF-kB signal pathway on folate-conjugated nanoparticle endocytosis by rat Kupffer cells.

Authors:  Hongbo Tang; Hongli Chen; Yajing Jia; Xiaoyan Liu; Zhaohong Han; Aihua Wang; Qi Liu; Xinlei Li; Xin Feng
Journal:  Int J Nanomedicine       Date:  2017-09-18

10.  Transferrin-Conjugated Docetaxel-PLGA Nanoparticles for Tumor Targeting: Influence on MCF-7 Cell Cycle.

Authors:  Sajan Jose; Cinu Thomas A; Rosmy Sebastian; Shoja M H; Aleykutty N A; Alessandra Durazzo; Massimo Lucarini; Antonello Santini; Eliana B Souto
Journal:  Polymers (Basel)       Date:  2019-11-19       Impact factor: 4.329
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.