Literature DB >> 28234240

In vivo study of osteogenerating properties of calcium-phosphate coating on titanium alloy Ti-6Al-4V.

Sergey V Gnedenkov1, Sergey L Sinebryukhov1, Artyom V Puz1, Vladimir S Egorkin1, Roman E Kostiv2.   

Abstract

The method of formation of bioactive calcium-phosphate coating on medical titanium alloy Ti-6Al-4V (3.5-5.3% V; 5.3-6.8% Al; balance -Ti) by plasma electrolytic oxidation (PEO) has been developed. Evaluation of osteogenerating properties of the coating at fractures of the shaft of the femur on Wistar line laboratory rats has been performed. It has been established that the calcium-phosphate PEO coating accelerates osteogenesis and promotes the formation of a pronounced periosteal callus in the fracture area. The presence of calcium phosphates in the PEO coating surface layer significantly accelerates the growth of bone tissue on the titanium surface.

Entities:  

Keywords:  Calcium-phosphate coatings; implant; osteogenesis; plasma electrolytic oxidation; titanium alloy Ti–6Al–4V

Mesh：

Substances：

Year:  2016        PMID： 28234240     DOI： 10.3233/BME-161608

Source DB:  PubMed          Journal:  Biomed Mater Eng        ISSN： 0959-2989            Impact factor:   1.300


  4 in total

1.  Direct comparison of additively manufactured porous titanium and tantalum implants towards in vivo osseointegration.

Authors:  Amit Bandyopadhyay; Indranath Mitra; Anish Shivaram; Nairanjana Dasgupta; Susmita Bose
Journal:  Addit Manuf       Date:  2019-05-01

2.  Effect of titanium dioxide intermediate layer on scratch and corrosion resistance of sol-gel-derived HA coating applied on Ti-6Al-4V substrate.

Authors:  Rezvan Azari; Hamid Reza Rezaie; Alireza Khavandi
Journal:  Prog Biomater       Date:  2021-11-06

3.  Modification of the Ceramic Implant Surfaces from Zirconia by the Magnetron Sputtering of Different Calcium Phosphate Targets: A Comparative Study.

Authors:  Anna I Kozelskaya; Evgeny N Bolbasov; Alexey S Golovkin; Alexander I Mishanin; Alice N Viknianshchuk; Evgeny V Shesterikov; Аndrey Ashrafov; Vadim A Novikov; Alexander Y Fedotkin; Igor A Khlusov; Sergey I Tverdokhlebov
Journal:  Materials (Basel)       Date:  2018-10-11       Impact factor: 3.623

4.  In-vivo performance of plasma-sprayed CaO-MgO-SiO2-based bioactive glass-ceramic coating on Ti-6Al-4V alloy for bone regeneration.

Authors:  Mengjiao Zhang; Ximing Pu; Xianchun Chen; Guangfu Yin
Journal:  Heliyon       Date:  2019-11-15
  4 in total

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