Literature DB >> 28233314

Less is more: the role of mTORC1 activation in the progression of ageing-mediated anabolic resistance.

Cory M Dungan1.   

Abstract

Entities:  

Keywords:  Ageing; anabolic resistance; mtor

Mesh：

Substances：

Year:  2017        PMID： 28233314      PMCID： PMC5407973          DOI： 10.1113/JP274154

Source DB:  PubMed          Journal:  J Physiol        ISSN： 0022-3751            Impact factor:   5.182


× No keyword cloud information.
  5 in total

1.  Blunted hypertrophic response in aged skeletal muscle is associated with decreased ribosome biogenesis.

Authors:  Tyler J Kirby; Jonah D Lee; Jonathan H England; Thomas Chaillou; Karyn A Esser; John J McCarthy
Journal:  J Appl Physiol (1985)       Date:  2015-06-05

2.  Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women.

Authors:  Melissa M Markofski; Jared M Dickinson; Micah J Drummond; Christopher S Fry; Satoshi Fujita; David M Gundermann; Erin L Glynn; Kristofer Jennings; Douglas Paddon-Jones; Paul T Reidy; Melinda Sheffield-Moore; Kyle L Timmerman; Blake B Rasmussen; Elena Volpi
Journal:  Exp Gerontol       Date:  2015-02-28       Impact factor: 4.032

3.  Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy.

Authors:  Perrine Castets; Shuo Lin; Nathalie Rion; Sabrina Di Fulvio; Klaas Romanino; Maitea Guridi; Stephan Frank; Lionel A Tintignac; Michael Sinnreich; Markus A Rüegg
Journal:  Cell Metab       Date:  2013-04-18       Impact factor: 27.287

4.  Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy.

Authors:  C Florian Bentzinger; Shuo Lin; Klaas Romanino; Perrine Castets; Maitea Guridi; Serge Summermatter; Christoph Handschin; Lionel A Tintignac; Michael N Hall; Markus A Rüegg
Journal:  Skelet Muscle       Date:  2013-03-06       Impact factor: 4.912

5.  Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age-related anabolic resistance to exercise in humans.

Authors:  Matthew S Brook; Daniel J Wilkinson; William K Mitchell; Jonathan N Lund; Bethan E Phillips; Nathaniel J Szewczyk; Paul L Greenhaff; Kenneth Smith; Philip J Atherton
Journal:  J Physiol       Date:  2016-11-07       Impact factor: 5.182
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.