Literature DB >> 28232730

Untangling the genetics from the epigenetics in pancreatic cancer metastasis.

Christopher R Vakoc1, David A Tuveson1.   

Abstract

Comparative genomic analyses of primary tumors and metastases within individuals with pancreatic cancer have exposed the complex clonal dynamics that underlie the dissemination of cancer cells to distant sites. Recent studies implicate non-genetic mechanisms in this process, particularly fluctuations in chromatin states and metabolism, which can endow rare cells within a primary tumor with metastatic potential.

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Year:  2017        PMID： 28232730     DOI： 10.1038/ng.3798

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  11 in total

Review 1.  The epigenetic progenitor origin of human cancer.

Authors:  Andrew P Feinberg; Rolf Ohlsson; Steven Henikoff
Journal:  Nat Rev Genet       Date:  2006-01       Impact factor: 53.242

Review 2.  Lessons from the cancer genome.

Authors:  Levi A Garraway; Eric S Lander
Journal:  Cell       Date:  2013-03-28       Impact factor: 41.582

3.  The patterns and dynamics of genomic instability in metastatic pancreatic cancer.

Authors:  Peter J Campbell; Shinichi Yachida; Laura J Mudie; Philip J Stephens; Erin D Pleasance; Lucy A Stebbings; Laura A Morsberger; Calli Latimer; Stuart McLaren; Meng-Lay Lin; David J McBride; Ignacio Varela; Serena A Nik-Zainal; Catherine Leroy; Mingming Jia; Andrew Menzies; Adam P Butler; Jon W Teague; Constance A Griffin; John Burton; Harold Swerdlow; Michael A Quail; Michael R Stratton; Christine Iacobuzio-Donahue; P Andrew Futreal
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Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-18       Impact factor: 11.205

Review 5.  The cancer genome.

Authors:  Michael R Stratton; Peter J Campbell; P Andrew Futreal
Journal:  Nature       Date:  2009-04-09       Impact factor: 49.962

6.  Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.

Authors:  Sarah K Denny; Dian Yang; Chen-Hua Chuang; Jennifer J Brady; Jing Shan Lim; Barbara M Grüner; Shin-Heng Chiou; Alicia N Schep; Jessika Baral; Cécile Hamard; Martine Antoine; Marie Wislez; Christina S Kong; Andrew J Connolly; Kwon-Sik Park; Julien Sage; William J Greenleaf; Monte M Winslow
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Journal:  Nature       Date:  2010-10-28       Impact factor: 49.962

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Authors:  Christopher Foster; Douglas Easton; Ultan McDermott; David C Wedge; G Steven Bova; Gunes Gundem; Peter Van Loo; Barbara Kremeyer; Ludmil B Alexandrov; Jose M C Tubio; Elli Papaemmanuil; Daniel S Brewer; Heini M L Kallio; Gunilla Högnäs; Matti Annala; Kati Kivinummi; Victoria Goody; Calli Latimer; Sarah O'Meara; Kevin J Dawson; William Isaacs; Michael R Emmert-Buck; Matti Nykter; Zsofia Kote-Jarai; Hayley C Whitaker; David E Neal; Colin S Cooper; Rosalind A Eeles; Tapio Visakorpi; Peter J Campbell
Journal:  Nature       Date:  2015-04-01       Impact factor: 49.962

Review 9.  Origins of metastatic traits.

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Authors:  William J Gibson; Erling A Hoivik; Mari K Halle; Amaro Taylor-Weiner; Andrew D Cherniack; Anna Berg; Frederik Holst; Travis I Zack; Henrica M J Werner; Kjersti M Staby; Mara Rosenberg; Ingunn M Stefansson; Kanthida Kusonmano; Aaron Chevalier; Karen K Mauland; Jone Trovik; Camilla Krakstad; Marios Giannakis; Eran Hodis; Kathrine Woie; Line Bjorge; Olav K Vintermyr; Jeremiah A Wala; Michael S Lawrence; Gad Getz; Scott L Carter; Rameen Beroukhim; Helga B Salvesen
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  8 in total

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Review 4.  A brief overview of antitumoral actions of bruceine D.

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Review 6.  Targeting Epigenetic Aberrations in Pancreatic Cancer, a New Path to Improve Patient Outcomes?

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  8 in total

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