Reza Safaralizadeh1, Narges Dastmalchi2, MohammadAli Hosseinpourfeizi3, Saeid Latifi-Navid4. 1. Department of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran. Electronic address: safaralizadeh@tabrizu.ac.ir. 2. Department of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran. Electronic address: n_dastmalchi93@tabrizu.ac.ir. 3. Department of Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran. Electronic address: pourfeizi@eastp.ir. 4. Department of Biology, Faculty of Sciences, University of Mohaghegh Ardabili, Ardabil, Iran. Electronic address: slatifin@yahoo.com.
Abstract
PURPOSES: Helicobacter pylori as an important pathogenic bacterium that colonizes in gastric mucosa, is one of the causative agents in development of some types of gastric diseases, such as chronic active gastritis, peptic ulcer disease (PUD) and gastric cancer (GC). In this review, the aim is studying different genotypes of H. pylori, and the extent of their participation in the pathogenesis of this bacterium which creates gastroduodenal disorders. RESULTS: Some genotypes of H. pylori have a major role in creation of gastroduodenal diseases, whereas some other genotypes of the bacterium do not cause gastric diseases in Iran. It was also reported that some genotypes of this bacterium in different conditions and among different ethnic groups demonstrate different effectiveness. CONCLUSION: Role of genotypes of H. pylori in creation of gastroduodenal diseases is different among various regions and ethnic groups of Iran.
PURPOSES: Helicobacter pylori as an important pathogenic bacterium that colonizes in gastric mucosa, is one of the causative agents in development of some types of gastric diseases, such as chronic active gastritis, peptic ulcer disease (PUD) and gastric cancer (GC). In this review, the aim is studying different genotypes of H. pylori, and the extent of their participation in the pathogenesis of this bacterium which creates gastroduodenal disorders. RESULTS: Some genotypes of H. pylori have a major role in creation of gastroduodenal diseases, whereas some other genotypes of the bacterium do not cause gastric diseases in Iran. It was also reported that some genotypes of this bacterium in different conditions and among different ethnic groups demonstrate different effectiveness. CONCLUSION: Role of genotypes of H. pylori in creation of gastroduodenal diseases is different among various regions and ethnic groups of Iran.
Authors: Igor Brasil-Costa; Cintya de Oliveira Souza; Leni Célia Reis Monteiro; Maria Elisabete Silva Santos; Edivaldo Herculano Correa De Oliveira; Rommel Mario Rodriguez Burbano Journal: Pathogens Date: 2022-03-29