Óscar Nogales1, Javier García-Lledó2, Marisol Luján3, David Nicolás4, José Francisco Juanmartiñena5, Begoña González-Suárez6, Francisco Sánchez Ceballos7, Ignacio Couto8, José Olmedo9, Cristina Garfia10, Cristina Carretero11, Ignacio Fernández Urién12, Sarbelio Rodríguez13, Matilde Asteinza14, Pilar Olivencia15, Ángeles Masedo16, Miguel Muñoz-Navas17, Beatriz Merino2, Cecilia González Asanza18. 1. Servicio Aparato Digestivo, Hospital General Universitario Gregorio Marañon, España. 2. Digestivo, Hospital General Universitario Gregorio Marañón. Madrid, ESPAÑA. 3. Digestivo, Hospital General Universitario de Valencia. 4. Digestivo, Hospital Universitario de Canarias. 5. Unidad de Endoscopia. Aparato Digestivo, Complejo Hospitalario de Navarra, españa. 6. Endoscopy Unit. Gastroenterology Department. , Hospital Clinic, Barcelona, España. 7. Digestivo, Hospital Clínico San Carlos, España. 8. CHU A Coruña. 9. Digestivo, HGUCR, ESPAÑA. 10. Digestivo, Hospital Universitario 12 de Octubre. 11. Digestivo, Clínica Universidad de Navarra, España. 12. Aparato Digestivo, Complejo Hospitalario de Navarra. 13. Aparato Digestivo, Hospital Universitario 12 de Octubre, España. 14. Aparato Digestivo, Hospital Clínico San Carlos. Madrid, ESPAÑA. 15. Cuidad Real, Hospital General Universitario de Ciudad Real, ESPAÑA. 16. Hospital Universitario 12 de Octubre. 17. Aparato Digestivo, Clínica Universidad de Navarra. 18. Aparato Digestivo, Hospital General Universitario Gregorio Marañón. Madrid, ESPAÑA.
Abstract
INTRODUCTION: Colon capsule endoscopy (CCE) is an alternative approach for the examination of the colon in patients who refuse colonoscopy or after incomplete colonoscopy (IC). We conducted a study to determine the frequency of complete colonoscopy after IC, the diagnostic yield of CCE, the therapeutic impact of lesions found in CCE, the level of colon cleanliness and the safety of the procedure. METHODS: We performed a prospective, multicenter study involving ten Spanish hospitals. Consecutive outpatients aged ≥ 18 years with previous IC were invited to participate. The latest version of the CCE device, PillCam™ COLON 2 (CCE-2), was administered to all patients according to the protocol. RESULTS: The study population comprised 96 patients. The most frequent cause of IC was the inability to move past a loop using standard maneuvers (75/96 patients, 78%). Complete visualization of the colon was obtained with CCE-2 in 69 patients (71.9%). Of the 27 patients in whom the CCE-2 did not reach the hemorrhoidal plexus, it passed the colonic segment explored with the previous colonoscopy in 20 cases; therefore, it could be inferred that a combined approach (CCE-2 plus colonoscopy) enabled complete visualization of the colonic mucosa in 92.7% of patients. CCE-2 revealed new lesions in 58 patients (60.4%). Polyps were the most frequent finding (41 patients; 42.7% of the total number of patients). In 43 of the 58 patients (44.8% of the total number of patients), the new lesions observed led to modification of therapy, which included a new colonoscopy for polyp resection or surgery in patients with colonic neoplasm. CONCLUSIONS: CCE-2 is a suitable diagnostic procedure that can lead to more frequent diagnosis of significant colonic lesions after IC.
INTRODUCTION: Colon capsule endoscopy (CCE) is an alternative approach for the examination of the colon in patients who refuse colonoscopy or after incomplete colonoscopy (IC). We conducted a study to determine the frequency of complete colonoscopy after IC, the diagnostic yield of CCE, the therapeutic impact of lesions found in CCE, the level of colon cleanliness and the safety of the procedure. METHODS: We performed a prospective, multicenter study involving ten Spanish hospitals. Consecutive outpatients aged ≥ 18 years with previous IC were invited to participate. The latest version of the CCE device, PillCam™ COLON 2 (CCE-2), was administered to all patients according to the protocol. RESULTS: The study population comprised 96 patients. The most frequent cause of IC was the inability to move past a loop using standard maneuvers (75/96 patients, 78%). Complete visualization of the colon was obtained with CCE-2 in 69 patients (71.9%). Of the 27 patients in whom the CCE-2 did not reach the hemorrhoidal plexus, it passed the colonic segment explored with the previous colonoscopy in 20 cases; therefore, it could be inferred that a combined approach (CCE-2 plus colonoscopy) enabled complete visualization of the colonic mucosa in 92.7% of patients. CCE-2 revealed new lesions in 58 patients (60.4%). Polyps were the most frequent finding (41 patients; 42.7% of the total number of patients). In 43 of the 58 patients (44.8% of the total number of patients), the new lesions observed led to modification of therapy, which included a new colonoscopy for polyp resection or surgery in patients with colonic neoplasm. CONCLUSIONS:CCE-2 is a suitable diagnostic procedure that can lead to more frequent diagnosis of significant colonic lesions after IC.
Authors: U Deding; J Herp; A-L Havshoei; M Kobaek-Larsen; M M Buijs; E S Nadimi; G Baatrup Journal: United European Gastroenterol J Date: 2020-08 Impact factor: 4.623
Authors: Cristiano Spada; Cesare Hassan; Davide Bellini; David Burling; Giovanni Cappello; Cristina Carretero; Evelien Dekker; Rami Eliakim; Margriet de Haan; Michal F Kaminski; Anastasios Koulaouzidis; Andrea Laghi; Philippe Lefere; Thomas Mang; Sebastian Manuel Milluzzo; Martina Morrin; Deirdre McNamara; Emanuele Neri; Silvia Pecere; Mathieu Pioche; Andrew Plumb; Emanuele Rondonotti; Manon Cw Spaander; Stuart Taylor; Ignacio Fernandez-Urien; Jeanin E van Hooft; Jaap Stoker; Daniele Regge Journal: Eur Radiol Date: 2021-05 Impact factor: 5.315