Literature DB >> 28228779

A retrospective study on screening and management of osteoporosis in breast cancer women treated with aromatase inhibitors in Libya.

Hanan Saaddedin Abushwereb1, M Elhabash2, S Elhamshari1, H Eshaefi1.   

Abstract

Negative health effects of aromatase inhibitors (AI) treatments on bones such as osteoporosis are evidenced. This impact of the aromatase inhibitors on bone. This study aimed to improve the medical assistance given to patients under AI treatment to minimize secondary osteoporosis. Fifty Libyan postmenopausal women treated with AI to fight breast cancer were selected from attendants Tripoli Medical Center (TMC), Oncology Department during year 2014. A closed questionnaire was requested from each women including data about age, age at AI therapy, and types of AI, age at bone densitometry measurement, onset and symptoms of osteoporosis, treatment of osteoporosis and measurement of vitamin D and calcium supplement given. The study revealed a poor consideration given to apply the recommendation in cases suffering osteoporosis events. Our results suggest an active implementation of the guidelines concerning the high corporation levels that should be done between oncologist, specialist in osteoporosis, and patients to offer reliable diagnostic and post-therapy follow up.

Entities:  

Keywords:  aromatase inhibitors; breast cancer; osteoporosis

Year:  2017        PMID: 28228779      PMCID: PMC5318169          DOI: 10.11138/ccmbm/2016.13.3.186

Source DB:  PubMed          Journal:  Clin Cases Miner Bone Metab        ISSN: 1724-8914


  21 in total

Review 1.  NCCN Task Force Report: Bone Health In Cancer Care.

Authors:  Julie R Gralow; J Sybil Biermann; Azeez Farooki; Monica N Fornier; Robert F Gagel; Rashmi Kumar; Georgia Litsas; Rana McKay; Donald A Podoloff; Sandy Srinivas; Catherine H Van Poznak
Journal:  J Natl Compr Canc Netw       Date:  2013-08       Impact factor: 11.908

Review 2.  American Society of Clinical Oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer.

Authors:  Harold J Burstein; Ann Alexis Prestrud; Jerome Seidenfeld; Holly Anderson; Thomas A Buchholz; Nancy E Davidson; Karen E Gelmon; Sharon H Giordano; Clifford A Hudis; Jennifer Malin; Eleftherios P Mamounas; Diana Rowden; Alexander J Solky; Maryfran R Sowers; Vered Stearns; Eric P Winer; Mark R Somerfield; Jennifer J Griggs
Journal:  J Clin Oncol       Date:  2010-07-12       Impact factor: 44.544

Review 3.  Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group.

Authors: 
Journal:  World Health Organ Tech Rep Ser       Date:  1994

4.  Impact of aromatase inhibitors on bone health in breast cancer patients.

Authors:  Jürgen Geisler; Per E Lønning
Journal:  J Steroid Biochem Mol Biol       Date:  2009-10-13       Impact factor: 4.292

5.  Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial.

Authors:  Christos Markopoulos; Evagelos Tzoracoleftherakis; Athanassios Polychronis; Basileios Venizelos; Urania Dafni; Grigorios Xepapadakis; John Papadiamantis; Vasilios Zobolas; John Misitzis; Kyriakos Kalogerakos; Angeliki Sarantopoulou; Nikolaos Siasos; Dimitrios Koukouras; Zoh Antonopoulou; Spyros Lazarou; Helen Gogas
Journal:  Breast Cancer Res       Date:  2010-04-16       Impact factor: 6.466

6.  A study of the effects of the aromatase inhibitors anastrozole and letrozole on bone metabolism in postmenopausal women with estrogen receptor-positive breast cancer.

Authors:  Fiona M McCaig; Lorna Renshaw; Linda Williams; Oliver Young; Juliette Murray; Elizabeth J Macaskill; Mary McHugh; Rosemary Hannon; J Michael Dixon
Journal:  Breast Cancer Res Treat       Date:  2010-02       Impact factor: 4.872

7.  Risedronate prevents bone loss in breast cancer survivors: a 2-year, randomized, double-blind, placebo-controlled clinical trial.

Authors:  Susan L Greenspan; Adam Brufsky; Barry C Lembersky; Rajib Bhattacharya; Karen T Vujevich; Subashan Perera; Susan M Sereika; Victor G Vogel
Journal:  J Clin Oncol       Date:  2008-04-21       Impact factor: 44.544

8.  Practical guidance for the management of aromatase inhibitor-associated bone loss.

Authors:  P Hadji; J-J Body; M S Aapro; A Brufsky; R E Coleman; T Guise; A Lipton; M Tubiana-Hulin
Journal:  Ann Oncol       Date:  2008-04-29       Impact factor: 32.976

9.  Zoledronic acid effectively prevents aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST study 36-month follow-up results.

Authors:  Adam M Brufsky; Linda D Bosserman; Richard R Caradonna; Barbara B Haley; C Michael Jones; Halle C F Moore; Lixian Jin; Ghulam M Warsi; Solveig G Ericson; Edith A Perez
Journal:  Clin Breast Cancer       Date:  2009-05       Impact factor: 3.225

10.  Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer.

Authors:  Georgiana K Ellis; Henry G Bone; Rowan Chlebowski; Devchand Paul; Silvana Spadafora; Judy Smith; Michelle Fan; Susie Jun
Journal:  J Clin Oncol       Date:  2008-08-25       Impact factor: 44.544

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