Literature DB >> 2822626

Synthesis and characterization of potential tumor scintigraphic agents.

A B Awaluddin1, J J Jacobs, D W Bourne, D J Maddalena, J G Wilson, R E Boyd.   

Abstract

Potential tumor imaging radiopharmaceutical agents have been prepared by attaching a cisplatin derivative to a ligand capable of forming a stable complex with 99mTc. Three new organometallic compounds, with iminodiacetic acid as the 99mTc chelating group and 2,3-diaminopropionamide as the platinum complexing group, have been prepared and characterized. Preliminary biodistribution studies in tumor bearing mice support the utility of this approach.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 2822626     DOI: 10.1016/0883-2889(87)90138-9

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum A        ISSN: 0883-2889


  1 in total

1.  Genotoxicity and cell cycle effects of platinum-based imaging agents in cisplatin-resistant human tumour cells.

Authors:  J Lean; P G Parsons; A B Awaluddin; J J Jacobs; D J Maddalena; J G Wilson; S K Khoo; C Ward
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.