Literature DB >> 2822599

In situ localization of human papilloma virus type 16 DNA in a metastasis of an endocervical adenocarcinoma.

J M Walboomers1, H E Fokke, M Polak, H Volkers, H J Houthoff, J Barents, J van der Noordaa, J ter Schegget.   

Abstract

Metastatic tissue from an endocervical adenocarcinoma was examined for human papilloma virus (HPV) DNA sequences. Southern blot analysis with 32P-labeled viral probes revealed the presence of about 150 copies of HPV-16 DNA per cellular genome. DNA in situ hybridization of frozen sections with biotinylated probes showed that HPV-16 DNA was exclusively detectable in the nuclei of the malignant epithelial cells and not in the stroma.

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Year:  1987        PMID： 2822599     DOI： 10.1159/000149723

Source DB:  PubMed          Journal:  Intervirology        ISSN： 0300-5526            Impact factor:   1.763


  7 in total

1.  Low doses of flagellin-L2 multimer vaccines protect against challenge with diverse papillomavirus genotypes.

Authors:  Kirill Kalnin; Timothy Tibbitts; Yanhua Yan; Svetlana Stegalkina; Lihua Shen; Victor Costa; Robert Sabharwal; Stephen F Anderson; Patricia M Day; Neil Christensen; John T Schiller; Subhashini Jagu; Richard B S Roden; Jeffrey Almond; Harold Kleanthous
Journal:  Vaccine       Date:  2014-04-26       Impact factor: 3.641

2.  Analysis by multiplex PCR of the physical status of human papillomavirus type 16 DNA in cervical cancers.

Authors:  M Yoshinouchi; A Hongo; K Nakamura; J Kodama; S Itoh; H Sakai; T Kudo
Journal:  J Clin Microbiol       Date:  1999-11       Impact factor: 5.948

3.  Human papillomavirus detection in paraffin-embedded cervical carcinomas and metastases of the carcinomas by the polymerase chain reaction.

Authors:  E C Claas; W J Melchers; H C van der Linden; J Lindeman; W G Quint
Journal:  Am J Pathol       Date:  1989-10       Impact factor: 4.307

4.  Metastatic conversion of cells by expression of human papillomavirus type 16 E6 and E7 genes.

Authors:  L Chen; S Ashe; M C Singhal; D A Galloway; I Hellström; K E Hellström
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-15       Impact factor: 11.205

5.  Sensitivity of in situ detection with biotinylated probes of human papilloma virus type 16 DNA in frozen tissue sections of squamous cell carcinomas of the cervix.

Authors:  J M Walboomers; W J Melchers; H Mullink; C J Meijer; A Struyk; W G Quint; J van der Noordaa; J ter Schegget
Journal:  Am J Pathol       Date:  1988-06       Impact factor: 4.307

6.  Amplification of human papillomavirus type 16 transforming genes from cervical cancer biopsies and lymph nodes of Hungarian patients.

Authors:  J Czeglédy; R Póka; G Veress; L Gergely
Journal:  J Clin Microbiol       Date:  1992-01       Impact factor: 5.948

7.  Detection of high-risk human papillomavirus subtypes in cervical glandular neoplasia by in situ hybridization.

Authors:  Zhang Sheng; Hiroshi Minato; Toshiyuki Sasagawa; Satoko Nakada; Eriko Kinoshita; Nozomu Kurose; Takayuki Nojima; Satoru Makinoda
Journal:  Int J Clin Exp Pathol       Date:  2013-09-15
  7 in total

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