Literature DB >> 28223701

NAFLD: A critical role for the NLRP3 inflammasome in NASH.

Hugh Thomas.   

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Year:  2017        PMID： 28223701     DOI： 10.1038/nrgastro.2017.21

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN： 1759-5045            Impact factor:   46.802


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  1 in total

1.  NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice.

Authors:  Auvro R Mridha; Alexander Wree; Avril A B Robertson; Matthew M Yeh; Casey D Johnson; Derrick M Van Rooyen; Fahrettin Haczeyni; Narci C-H Teoh; Christopher Savard; George N Ioannou; Seth L Masters; Kate Schroder; Matthew A Cooper; Ariel E Feldstein; Geoffrey C Farrell
Journal:  J Hepatol       Date:  2017-02-03       Impact factor: 25.083
  1 in total
  17 in total

1.  ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.

Authors:  Susanne Schuster-Gaul; Lukas Jonathan Geisler; Matthew D McGeough; Casey D Johnson; Anna Zagorska; Li Li; Alexander Wree; Vivian Barry; Igor Mikaelian; Lily J Jih; Bettina G Papouchado; Grant Budas; Hal M Hoffman; Ariel E Feldstein
Journal:  JCI Insight       Date:  2020-01-30

2.  Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.

Authors:  Qiang Li; Hui Feng; Hongbo Wang; Yinghao Wang; Wenqing Mou; Guang Xu; Ping Zhang; Ruisheng Li; Wei Shi; Zhilei Wang; Zhie Fang; Lutong Ren; Yan Wang; Li Lin; Xiaorong Hou; Wenzhang Dai; Zhiyong Li; Ziying Wei; Tingting Liu; Jiabo Wang; Yuming Guo; Pengyan Li; Xu Zhao; Xiaoyan Zhan; Xiaohe Xiao; Zhaofang Bai
Journal:  EMBO Rep       Date:  2021-12-09       Impact factor: 8.807

3.  The P2X7R-NLRP3 and AIM2 Inflammasome Platforms Mark the Complexity/Severity of Viral or Metabolic Liver Damage.

Authors:  Chiara Rossi; Antonio Salvati; Mariarosaria Distaso; Daniela Campani; Francesco Raggi; Edoardo Biancalana; Domenico Tricò; Maurizia Rossana Brunetto; Anna Solini
Journal:  Int J Mol Sci       Date:  2022-07-04       Impact factor: 6.208

4.  Rhubarb free anthraquinones improved mice nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome.

Authors:  Chao Wu; Yanqin Bian; Bingjie Lu; Dan Wang; Nisma Lena Bahaji Azami; Gang Wei; Feng Ma; Mingyu Sun
Journal:  J Transl Med       Date:  2022-06-28       Impact factor: 8.440

5.  The role of REV-ERB in NASH.

Authors:  Kristine Griffett; Matthew E Hayes; Michael P Boeckman; Thomas P Burris
Journal:  Acta Pharmacol Sin       Date:  2022-02-25       Impact factor: 7.169

6.  Cathepsin B inhibition ameliorates the non-alcoholic steatohepatitis through suppressing caspase-1 activation.

Authors:  Yong Tang; Guojun Cao; Xiaobo Min; Tao Wang; Shiran Sun; Xiaolong Du; Weikang Zhang
Journal:  J Physiol Biochem       Date:  2018-07-17       Impact factor: 4.158

Review 7.  Autophagy in liver diseases.

Authors:  Elias Kouroumalis; Argryro Voumvouraki; Aikaterini Augoustaki; Dimitrios N Samonakis
Journal:  World J Hepatol       Date:  2021-01-27

8.  NLRP3 Inflammasome Formation and Activation in Nonalcoholic Steatohepatitis: Therapeutic Target for Antimetabolic Syndrome Remedy FTZ.

Authors:  Yu Chen; Xingxiang He; Xinxu Yuan; Jinni Hong; Owais Bhat; Guangbi Li; Pin-Lan Li; Jiao Guo
Journal:  Oxid Med Cell Longev       Date:  2018-07-22       Impact factor: 6.543

9.  Trichloroethene metabolite dichloroacetyl chloride induces apoptosis and compromises phagocytosis in Kupffer Cells: Activation of inflammasome and MAPKs.

Authors:  Hui Wang; Gangduo Wang; G A Shakeel Ansari; M Firoze Khan
Journal:  PLoS One       Date:  2018-12-31       Impact factor: 3.240

10.  Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct-Ligated Mouse.

Authors:  Shi-Ying Cai; Maoxu Ge; Albert Mennone; Rafaz Hoque; Xinshou Ouyang; James L Boyer
Journal:  Cell Mol Gastroenterol Hepatol       Date:  2019-12-27
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