Literature DB >> 28223325

Mendelian Randomization: Using Natural Genetic Variation to Assess the Causal Role of Modifiable Risk Factors in Observational Studies.

Ian J Neeland1, Julia Kozlitina1.   

Abstract

Entities:  

Keywords:  Editorials; atrial fibrillation; genetic association studies; genetics; obesity

Mesh：

Year:  2017        PMID： 28223325      PMCID： PMC5324731          DOI： 10.1161/CIRCULATIONAHA.117.026857

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  14 in total

1.  Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype.

Authors:  Nicholas J Timpson; Roger Harbord; George Davey Smith; Jeppe Zacho; Anne Tybjaerg-Hansen; Børge G Nordestgaard
Journal:  Hypertension       Date:  2009-05-26       Impact factor: 10.190

2.  Body fat distribution and incident cardiovascular disease in obese adults.

Authors:  Ian J Neeland; Aslan T Turer; Colby R Ayers; Jarett D Berry; Anand Rohatgi; Sandeep R Das; Amit Khera; Gloria L Vega; Darren K McGuire; Scott M Grundy; James A de Lemos
Journal:  J Am Coll Cardiol       Date:  2015-05-19       Impact factor: 24.094

3.  Overweight and obesity as risk factors for atrial fibrillation or flutter: the Danish Diet, Cancer, and Health Study.

Authors:  Lars Frost; Lone Juul Hune; Peter Vestergaard
Journal:  Am J Med       Date:  2005-05       Impact factor: 4.965

4.  Atrial fibrillation and obesity--results of a meta-analysis.

Authors:  Nikolas Wanahita; Franz H Messerli; Sripal Bangalore; Apoor S Gami; Virend K Somers; Jonathan S Steinberg
Journal:  Am Heart J       Date:  2007-12-19       Impact factor: 4.749

5.  Bariatric Surgery and the Risk of New-Onset Atrial Fibrillation in Swedish Obese Subjects.

Authors:  Shabbar Jamaly; Lena Carlsson; Markku Peltonen; Peter Jacobson; Lars Sjöström; Kristjan Karason
Journal:  J Am Coll Cardiol       Date:  2016-12-13       Impact factor: 24.094

6.  Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.

Authors:  Amit V Khera; Connor A Emdin; Isabel Drake; Pradeep Natarajan; Alexander G Bick; Nancy R Cook; Daniel I Chasman; Usman Baber; Roxana Mehran; Daniel J Rader; Valentin Fuster; Eric Boerwinkle; Olle Melander; Marju Orho-Melander; Paul M Ridker; Sekar Kathiresan
Journal:  N Engl J Med       Date:  2016-11-13       Impact factor: 91.245

7.  Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization.

Authors:  Franco Giulianini; Bastiaan Geelhoed; Kathryn L Lunetta; Jeffrey R Misialek; Maartje N Niemeijer; Michiel Rienstra; Lynda M Rose; Albert V Smith; Neal A Chatterjee; Dan E Arking; Patrick T Ellinor; Jan Heeringa; Honghuang Lin; Steven A Lubitz; Elsayed Z Soliman; Niek Verweij; Alvaro Alonso; Emelia J Benjamin; Vilmundur Gudnason; Bruno H C Stricker; Pim Van Der Harst; Daniel I Chasman; Christine M Albert
Journal:  Circulation       Date:  2016-12-14       Impact factor: 29.690

8.  Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Authors:  Elizabeth K Speliotes; Cristen J Willer; Sonja I Berndt; Keri L Monda; Gudmar Thorleifsson; Anne U Jackson; Hana Lango Allen; Cecilia M Lindgren; Jian'an Luan; Reedik Mägi; Joshua C Randall; Sailaja Vedantam; Thomas W Winkler; Lu Qi; Tsegaselassie Workalemahu; Iris M Heid; Valgerdur Steinthorsdottir; Heather M Stringham; Michael N Weedon; Eleanor Wheeler; Andrew R Wood; Teresa Ferreira; Robert J Weyant; Ayellet V Segrè; Karol Estrada; Liming Liang; James Nemesh; Ju-Hyun Park; Stefan Gustafsson; Tuomas O Kilpeläinen; Jian Yang; Nabila Bouatia-Naji; Tõnu Esko; Mary F Feitosa; Zoltán Kutalik; Massimo Mangino; Soumya Raychaudhuri; Andre Scherag; Albert Vernon Smith; Ryan Welch; Jing Hua Zhao; Katja K Aben; Devin M Absher; Najaf Amin; Anna L Dixon; Eva Fisher; Nicole L Glazer; Michael E Goddard; Nancy L Heard-Costa; Volker Hoesel; Jouke-Jan Hottenga; Asa Johansson; Toby Johnson; Shamika Ketkar; Claudia Lamina; Shengxu Li; Miriam F Moffatt; Richard H Myers; Narisu Narisu; John R B Perry; Marjolein J Peters; Michael Preuss; Samuli Ripatti; Fernando Rivadeneira; Camilla Sandholt; Laura J Scott; Nicholas J Timpson; Jonathan P Tyrer; Sophie van Wingerden; Richard M Watanabe; Charles C White; Fredrik Wiklund; Christina Barlassina; Daniel I Chasman; Matthew N Cooper; John-Olov Jansson; Robert W Lawrence; Niina Pellikka; Inga Prokopenko; Jianxin Shi; Elisabeth Thiering; Helene Alavere; Maria T S Alibrandi; Peter Almgren; Alice M Arnold; Thor Aspelund; Larry D Atwood; Beverley Balkau; Anthony J Balmforth; Amanda J Bennett; Yoav Ben-Shlomo; Richard N Bergman; Sven Bergmann; Heike Biebermann; Alexandra I F Blakemore; Tanja Boes; Lori L Bonnycastle; Stefan R Bornstein; Morris J Brown; Thomas A Buchanan; Fabio Busonero; Harry Campbell; Francesco P Cappuccio; Christine Cavalcanti-Proença; Yii-Der Ida Chen; Chih-Mei Chen; Peter S Chines; Robert Clarke; Lachlan Coin; John Connell; Ian N M Day; Martin den Heijer; Jubao Duan; Shah Ebrahim; Paul Elliott; Roberto Elosua; Gudny Eiriksdottir; Michael R Erdos; Johan G Eriksson; Maurizio F Facheris; Stephan B Felix; Pamela Fischer-Posovszky; Aaron R Folsom; Nele Friedrich; Nelson B Freimer; Mao Fu; Stefan Gaget; Pablo V Gejman; Eco J C Geus; Christian Gieger; Anette P Gjesing; Anuj Goel; Philippe Goyette; Harald Grallert; Jürgen Grässler; Danielle M Greenawalt; Christopher J Groves; Vilmundur Gudnason; Candace Guiducci; Anna-Liisa Hartikainen; Neelam Hassanali; Alistair S Hall; Aki S Havulinna; Caroline Hayward; Andrew C Heath; Christian Hengstenberg; Andrew A Hicks; Anke Hinney; Albert Hofman; Georg Homuth; Jennie Hui; Wilmar Igl; Carlos Iribarren; Bo Isomaa; Kevin B Jacobs; Ivonne Jarick; Elizabeth Jewell; Ulrich John; Torben Jørgensen; Pekka Jousilahti; Antti Jula; Marika Kaakinen; Eero Kajantie; Lee M Kaplan; Sekar Kathiresan; Johannes Kettunen; Leena Kinnunen; Joshua W Knowles; Ivana Kolcic; Inke R König; Seppo Koskinen; Peter Kovacs; Johanna Kuusisto; Peter Kraft; Kirsti Kvaløy; Jaana Laitinen; Olivier Lantieri; Chiara Lanzani; Lenore J Launer; Cecile Lecoeur; Terho Lehtimäki; Guillaume Lettre; Jianjun Liu; Marja-Liisa Lokki; Mattias Lorentzon; Robert N Luben; Barbara Ludwig; Paolo Manunta; Diana Marek; Michel Marre; Nicholas G Martin; Wendy L McArdle; Anne McCarthy; Barbara McKnight; Thomas Meitinger; Olle Melander; David Meyre; Kristian Midthjell; Grant W Montgomery; Mario A Morken; Andrew P Morris; Rosanda Mulic; Julius S Ngwa; Mari Nelis; Matt J Neville; Dale R Nyholt; Christopher J O'Donnell; Stephen O'Rahilly; Ken K Ong; Ben Oostra; Guillaume Paré; Alex N Parker; Markus Perola; Irene Pichler; Kirsi H Pietiläinen; Carl G P Platou; Ozren Polasek; Anneli Pouta; Suzanne Rafelt; Olli Raitakari; Nigel W Rayner; Martin Ridderstråle; Winfried Rief; Aimo Ruokonen; Neil R Robertson; Peter Rzehak; Veikko Salomaa; Alan R Sanders; Manjinder S Sandhu; Serena Sanna; Jouko Saramies; Markku J Savolainen; Susann Scherag; Sabine Schipf; Stefan Schreiber; Heribert Schunkert; Kaisa Silander; Juha Sinisalo; David S Siscovick; Jan H Smit; Nicole Soranzo; Ulla Sovio; Jonathan Stephens; Ida Surakka; Amy J Swift; Mari-Liis Tammesoo; Jean-Claude Tardif; Maris Teder-Laving; Tanya M Teslovich; John R Thompson; Brian Thomson; Anke Tönjes; Tiinamaija Tuomi; Joyce B J van Meurs; Gert-Jan van Ommen; Vincent Vatin; Jorma Viikari; Sophie Visvikis-Siest; Veronique Vitart; Carla I G Vogel; Benjamin F Voight; Lindsay L Waite; Henri Wallaschofski; G Bragi Walters; Elisabeth Widen; Susanna Wiegand; Sarah H Wild; Gonneke Willemsen; Daniel R Witte; Jacqueline C Witteman; Jianfeng Xu; Qunyuan Zhang; Lina Zgaga; Andreas Ziegler; Paavo Zitting; John P Beilby; I Sadaf Farooqi; Johannes Hebebrand; Heikki V Huikuri; Alan L James; Mika Kähönen; Douglas F Levinson; Fabio Macciardi; Markku S Nieminen; Claes Ohlsson; Lyle J Palmer; Paul M Ridker; Michael Stumvoll; Jacques S Beckmann; Heiner Boeing; Eric Boerwinkle; Dorret I Boomsma; Mark J Caulfield; Stephen J Chanock; Francis S Collins; L Adrienne Cupples; George Davey Smith; Jeanette Erdmann; Philippe Froguel; Henrik Grönberg; Ulf Gyllensten; Per Hall; Torben Hansen; Tamara B Harris; Andrew T Hattersley; Richard B Hayes; Joachim Heinrich; Frank B Hu; Kristian Hveem; Thomas Illig; Marjo-Riitta Jarvelin; Jaakko Kaprio; Fredrik Karpe; Kay-Tee Khaw; Lambertus A Kiemeney; Heiko Krude; Markku Laakso; Debbie A Lawlor; Andres Metspalu; Patricia B Munroe; Willem H Ouwehand; Oluf Pedersen; Brenda W Penninx; Annette Peters; Peter P Pramstaller; Thomas Quertermous; Thomas Reinehr; Aila Rissanen; Igor Rudan; Nilesh J Samani; Peter E H Schwarz; Alan R Shuldiner; Timothy D Spector; Jaakko Tuomilehto; Manuela Uda; André Uitterlinden; Timo T Valle; Martin Wabitsch; Gérard Waeber; Nicholas J Wareham; Hugh Watkins; James F Wilson; Alan F Wright; M Carola Zillikens; Nilanjan Chatterjee; Steven A McCarroll; Shaun Purcell; Eric E Schadt; Peter M Visscher; Themistocles L Assimes; Ingrid B Borecki; Panos Deloukas; Caroline S Fox; Leif C Groop; Talin Haritunians; David J Hunter; Robert C Kaplan; Karen L Mohlke; Jeffrey R O'Connell; Leena Peltonen; David Schlessinger; David P Strachan; Cornelia M van Duijn; H-Erich Wichmann; Timothy M Frayling; Unnur Thorsteinsdottir; Gonçalo R Abecasis; Inês Barroso; Michael Boehnke; Kari Stefansson; Kari E North; Mark I McCarthy; Joel N Hirschhorn; Erik Ingelsson; Ruth J F Loos
Journal:  Nat Genet       Date:  2010-10-10       Impact factor: 38.330

9.  Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology.

Authors:  George Davey Smith; Debbie A Lawlor; Roger Harbord; Nic Timpson; Ian Day; Shah Ebrahim
Journal:  PLoS Med       Date:  2007-12       Impact factor: 11.069

10.  Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.

Authors:  Sonja I Berndt; Stefan Gustafsson; Reedik Mägi; Andrea Ganna; Eleanor Wheeler; Mary F Feitosa; Anne E Justice; Keri L Monda; Damien C Croteau-Chonka; Felix R Day; Tõnu Esko; Tove Fall; Teresa Ferreira; Davide Gentilini; Anne U Jackson; Jian'an Luan; Joshua C Randall; Sailaja Vedantam; Cristen J Willer; Thomas W Winkler; Andrew R Wood; Tsegaselassie Workalemahu; Yi-Juan Hu; Sang Hong Lee; Liming Liang; Dan-Yu Lin; Josine L Min; Benjamin M Neale; Gudmar Thorleifsson; Jian Yang; Eva Albrecht; Najaf Amin; Jennifer L Bragg-Gresham; Gemma Cadby; Martin den Heijer; Niina Eklund; Krista Fischer; Anuj Goel; Jouke-Jan Hottenga; Jennifer E Huffman; Ivonne Jarick; Åsa Johansson; Toby Johnson; Stavroula Kanoni; Marcus E Kleber; Inke R König; Kati Kristiansson; Zoltán Kutalik; Claudia Lamina; Cecile Lecoeur; Guo Li; Massimo Mangino; Wendy L McArdle; Carolina Medina-Gomez; Martina Müller-Nurasyid; Julius S Ngwa; Ilja M Nolte; Lavinia Paternoster; Sonali Pechlivanis; Markus Perola; Marjolein J Peters; Michael Preuss; Lynda M Rose; Jianxin Shi; Dmitry Shungin; Albert Vernon Smith; Rona J Strawbridge; Ida Surakka; Alexander Teumer; Mieke D Trip; Jonathan Tyrer; Jana V Van Vliet-Ostaptchouk; Liesbeth Vandenput; Lindsay L Waite; Jing Hua Zhao; Devin Absher; Folkert W Asselbergs; Mustafa Atalay; Antony P Attwood; Anthony J Balmforth; Hanneke Basart; John Beilby; Lori L Bonnycastle; Paolo Brambilla; Marcel Bruinenberg; Harry Campbell; Daniel I Chasman; Peter S Chines; Francis S Collins; John M Connell; William O Cookson; Ulf de Faire; Femmie de Vegt; Mariano Dei; Maria Dimitriou; Sarah Edkins; Karol Estrada; David M Evans; Martin Farrall; Marco M Ferrario; Jean Ferrières; Lude Franke; Francesca Frau; Pablo V Gejman; Harald Grallert; Henrik Grönberg; Vilmundur Gudnason; Alistair S Hall; Per Hall; Anna-Liisa Hartikainen; Caroline Hayward; Nancy L Heard-Costa; Andrew C Heath; Johannes Hebebrand; Georg Homuth; Frank B Hu; Sarah E Hunt; Elina Hyppönen; Carlos Iribarren; Kevin B Jacobs; John-Olov Jansson; Antti Jula; Mika Kähönen; Sekar Kathiresan; Frank Kee; Kay-Tee Khaw; Mika Kivimäki; Wolfgang Koenig; Aldi T Kraja; Meena Kumari; Kari Kuulasmaa; Johanna Kuusisto; Jaana H Laitinen; Timo A Lakka; Claudia Langenberg; Lenore J Launer; Lars Lind; Jaana Lindström; Jianjun Liu; Antonio Liuzzi; Marja-Liisa Lokki; Mattias Lorentzon; Pamela A Madden; Patrik K Magnusson; Paolo Manunta; Diana Marek; Winfried März; Irene Mateo Leach; Barbara McKnight; Sarah E Medland; Evelin Mihailov; Lili Milani; Grant W Montgomery; Vincent Mooser; Thomas W Mühleisen; Patricia B Munroe; Arthur W Musk; Narisu Narisu; Gerjan Navis; George Nicholson; Ellen A Nohr; Ken K Ong; Ben A Oostra; Colin N A Palmer; Aarno Palotie; John F Peden; Nancy Pedersen; Annette Peters; Ozren Polasek; Anneli Pouta; Peter P Pramstaller; Inga Prokopenko; Carolin Pütter; Aparna Radhakrishnan; Olli Raitakari; Augusto Rendon; Fernando Rivadeneira; Igor Rudan; Timo E Saaristo; Jennifer G Sambrook; Alan R Sanders; Serena Sanna; Jouko Saramies; Sabine Schipf; Stefan Schreiber; Heribert Schunkert; So-Youn Shin; Stefano Signorini; Juha Sinisalo; Boris Skrobek; Nicole Soranzo; Alena Stančáková; Klaus Stark; Jonathan C Stephens; Kathleen Stirrups; Ronald P Stolk; Michael Stumvoll; Amy J Swift; Eirini V Theodoraki; Barbara Thorand; David-Alexandre Tregouet; Elena Tremoli; Melanie M Van der Klauw; Joyce B J van Meurs; Sita H Vermeulen; Jorma Viikari; Jarmo Virtamo; Veronique Vitart; Gérard Waeber; Zhaoming Wang; Elisabeth Widén; Sarah H Wild; Gonneke Willemsen; Bernhard R Winkelmann; Jacqueline C M Witteman; Bruce H R Wolffenbuttel; Andrew Wong; Alan F Wright; M Carola Zillikens; Philippe Amouyel; Bernhard O Boehm; Eric Boerwinkle; Dorret I Boomsma; Mark J Caulfield; Stephen J Chanock; L Adrienne Cupples; Daniele Cusi; George V Dedoussis; Jeanette Erdmann; Johan G Eriksson; Paul W Franks; Philippe Froguel; Christian Gieger; Ulf Gyllensten; Anders Hamsten; Tamara B Harris; Christian Hengstenberg; Andrew A Hicks; Aroon Hingorani; Anke Hinney; Albert Hofman; Kees G Hovingh; Kristian Hveem; Thomas Illig; Marjo-Riitta Jarvelin; Karl-Heinz Jöckel; Sirkka M Keinanen-Kiukaanniemi; Lambertus A Kiemeney; Diana Kuh; Markku Laakso; Terho Lehtimäki; Douglas F Levinson; Nicholas G Martin; Andres Metspalu; Andrew D Morris; Markku S Nieminen; Inger Njølstad; Claes Ohlsson; Albertine J Oldehinkel; Willem H Ouwehand; Lyle J Palmer; Brenda Penninx; Chris Power; Michael A Province; Bruce M Psaty; Lu Qi; Rainer Rauramaa; Paul M Ridker; Samuli Ripatti; Veikko Salomaa; Nilesh J Samani; Harold Snieder; Thorkild I A Sørensen; Timothy D Spector; Kari Stefansson; Anke Tönjes; Jaakko Tuomilehto; André G Uitterlinden; Matti Uusitupa; Pim van der Harst; Peter Vollenweider; Henri Wallaschofski; Nicholas J Wareham; Hugh Watkins; H-Erich Wichmann; James F Wilson; Goncalo R Abecasis; Themistocles L Assimes; Inês Barroso; Michael Boehnke; Ingrid B Borecki; Panos Deloukas; Caroline S Fox; Timothy Frayling; Leif C Groop; Talin Haritunian; Iris M Heid; David Hunter; Robert C Kaplan; Fredrik Karpe; Miriam F Moffatt; Karen L Mohlke; Jeffrey R O'Connell; Yudi Pawitan; Eric E Schadt; David Schlessinger; Valgerdur Steinthorsdottir; David P Strachan; Unnur Thorsteinsdottir; Cornelia M van Duijn; Peter M Visscher; Anna Maria Di Blasio; Joel N Hirschhorn; Cecilia M Lindgren; Andrew P Morris; David Meyre; André Scherag; Mark I McCarthy; Elizabeth K Speliotes; Kari E North; Ruth J F Loos; Erik Ingelsson
Journal:  Nat Genet       Date:  2013-04-07       Impact factor: 38.330
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  5 in total

1.  Obesity: Obesity and cardiometabolic disease - more than meets the eye.

Authors:  Stella Aslibekyan; W Timothy Garvey
Journal:  Nat Rev Endocrinol       Date:  2017-09-01       Impact factor: 43.330

2.  Maternal central obesity and birth size: a Mendelian randomization analysis.

Authors:  Ting-Ting Geng; Tao Huang
Journal:  Lipids Health Dis       Date:  2018-07-31       Impact factor: 3.876

3.  Mendelian Randomization Analysis Support Causal Associations of HbA1c with Circulating Triglyceride, Total and Low-density Lipoprotein Cholesterol in a Chinese Population.

Authors:  Xu Jia; Yanan Hou; Min Xu; Zhiyun Zhao; Liping Xuan; Tiange Wang; Mian Li; Yu Xu; Jieli Lu; Yufang Bi; Weiqing Wang; Yuhong Chen
Journal:  Sci Rep       Date:  2019-04-02       Impact factor: 4.379

4.  Novel insights into the consequences of obesity: a phenotype-wide Mendelian randomization study.

Authors:  Liying Wang; Qing Wang; Peng Chen; Chang He; Miaoran Zhang; Jiuling Li; Yiqing Wang; Lanlan Chen; Baiyu Qi; Jianping Wen; Jianli Yang; Sitong Lin; Dianyuan Liu; Ying Dong
Journal:  Eur J Hum Genet       Date:  2022-01-01       Impact factor: 5.351

5.  Genetically Predicted Blood Pressure and Risk of Atrial Fibrillation.

Authors:  Matthew C Hyman; Michael G Levin; Dipender Gill; Venexia M Walker; Marios K Georgakis; Neil M Davies; Francis E Marchlinski; Scott M Damrauer
Journal:  Hypertension       Date:  2021-01-04       Impact factor: 10.190
  5 in total

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