Literature DB >> 28222404

Glycemic control in patients with insulinoma.

Agata Matej1, Hanna Bujwid2, Jakub Wroński3,4.   

Abstract

Insulinoma is the most common neuroendocrine tumor of the pancreas. Surgical management of insulinomas is considered to be the only curative method. However, effective glycemic control preoperatively and in unresectable insulinomas remains a significant issue. Hyperinsulinism, occurring as a result of the hormone-secreting tumor, leads to life-threatening hypoglycemia episodes which require urgent medical treatment. This article discusses current management of hypoglycemia in insulinoma patients, including: education and lifestyle modifications, pharmacotherapy (diazoxide, somatostatin analogs, mTOR inhibitor - everolimus), cytoreductive methods and continuous glucose monitoring systems.

Entities:  

Mesh：

Year:  2016        PMID： 28222404     DOI： 10.14310/horm.2002.1706

Source DB:  PubMed          Journal:  Hormones (Athens)        ISSN： 1109-3099            Impact factor:   2.885


  12 in total

Review 1.  The functioning side of the pancreas: a review on insulinomas.

Authors:  I Maggio; V Mollica; N Brighi; G Lamberti; L Manuzzi; A D Ricci; D Campana
Journal:  J Endocrinol Invest       Date:  2019-07-31       Impact factor: 4.256

Review 2.  Supportive therapy in gastroenteropancreatic neuroendocrine tumors: Often forgotten but important.

Authors:  Xi-Feng Jin; Matilde P Spampatti; Christine Spitzweg; Christoph J Auernhammer
Journal:  Rev Endocr Metab Disord       Date:  2018-06       Impact factor: 6.514

Review 3.  Case Report: Hypoglycemia Due to Metastatic Insulinoma in Insulin-Dependent Type 2 Diabetes Successfully Treated With 177 Lu-DOTATATE.

Authors:  Shejil Kumar; Mariah Melek; Peter Rohl
Journal:  Front Endocrinol (Lausanne)       Date:  2022-05-24       Impact factor: 6.055

4.  METNET: a phase II trial of metformin in patients with well-differentiated neuroendocrine tumours.

Authors:  João Glasberg; Aley Talans; Thomás Rivelli Giollo; Débora Zachello Recchimuzzi; João Evangelista Bezerra Neto; Rossana Veronica Mendonza Lopez; Paulo Marcelo Gehm Hoff; Rachel P Riechelmann
Journal:  Ecancermedicalscience       Date:  2022-03-31

Review 5.  Recent advances in diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms.

Authors:  Meng Dai; Christina S Mullins; Lili Lu; Guido Alsfasser; Michael Linnebacher
Journal:  World J Gastrointest Surg       Date:  2022-05-27

Review 6.  Carcinoid Syndrome and Hyperinsulinemic Hypoglycemia Associated with Neuroendocrine Neoplasms: A Critical Review on Clinical and Pharmacological Management.

Authors:  Francesca Spada; Roberta E Rossi; Elda Kara; Alice Laffi; Sara Massironi; Manila Rubino; Franco Grimaldi; Sherrie Bhoori; Nicola Fazio
Journal:  Pharmaceuticals (Basel)       Date:  2021-06-04

7.  Pasireotide: A Novel Treatment for Tumor-Induced Hypoglycemia Due to Insulinoma and Non-Islet Cell Tumor Hypoglycemia.

Authors:  Mahwash Siddiqui; Amy Vora; Sadia Ali; Jessica Abramowitz; Sasan Mirfakhraee
Journal:  J Endocr Soc       Date:  2020-11-05

Review 8.  Updated Principles of Surgical Management of Pancreatic Neuroendocrine Tumours (pNETs): What Every Surgeon Needs to Know.

Authors:  Charles de Ponthaud; Fabrice Menegaux; Sébastien Gaujoux
Journal:  Cancers (Basel)       Date:  2021-11-27       Impact factor: 6.639

9.  A pediatric case of insulinoma and a novel MEN1 mutation: the efficacy of the combination therapy of diazoxide and cornstarch.

Authors:  Satsuki Nakano; Takeshi Sato; Mayumi Hosokawa; Chisato Takagi; Fumiko Yoshida; Tomohiro Ishii; Seiji Sato; Tomonobu Hasegawa
Journal:  Clin Pediatr Endocrinol       Date:  2018-07-31

10.  Insulin autoimmune syndrome induced by exogenous insulin injection: a four-case series.

Authors:  Yimin Shen; Xiaoxiao Song; Yuezhong Ren
Journal:  BMC Endocr Disord       Date:  2019-12-28       Impact factor: 2.763
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.