Literature DB >> 28219911

Triple-negative breast cancer with brain metastasis in a pregnant woman.

Francisco Trinca1, Mariana Inácio1, Teresa Timóteo2, Rui Dinis1.   

Abstract

A woman aged 35 years was diagnosed with triple-negative breast cancer in October 2012. During the investigation, it was discovered that she was pregnant, the patient decided to have an abortion. She was submitted to a radical modified mastectomy and adjuvant chemotherapy followed by adjuvant breast radiotherapy of the left breast. 2 months after the adjuvant treatment, she began to have headaches and dizziness. The cranial MRI (head MRI) showed brain metastasis. She was then treated with whole brain radiotherapy, stereotactic radiosurgery and concomitant temozolomide which resulted in complete response. 1.5 year later, she was able to get pregnant and gave birth to a baby without complications. The previous imaging reassessment performed in September 2016 shows no evidence of recurrent breast cancer. 2017 BMJ Publishing Group Ltd.

Entities:  

Mesh:

Year:  2017        PMID: 28219911      PMCID: PMC5318606          DOI: 10.1136/bcr-2016-218657

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  23 in total

Review 1.  CNS metastases in breast cancer.

Authors:  Nancy U Lin; Jennifer R Bellon; Eric P Winer
Journal:  J Clin Oncol       Date:  2004-09-01       Impact factor: 44.544

2.  Absorption, metabolism, and excretion of 14C-temozolomide following oral administration to patients with advanced cancer.

Authors:  S D Baker; M Wirth; P Statkevich; P Reidenberg; K Alton; S E Sartorius; M Dugan; D Cutler; V Batra; L B Grochow; R C Donehower; E K Rowinsky
Journal:  Clin Cancer Res       Date:  1999-02       Impact factor: 12.531

3.  Radiosurgery for solitary brain metastases using the cobalt-60 gamma unit: methods and results in 24 patients.

Authors:  R J Coffey; J C Flickinger; D J Bissonette; L D Lunsford
Journal:  Int J Radiat Oncol Biol Phys       Date:  1991-06       Impact factor: 7.038

Review 4.  Breast cancer in pregnancy: a literature review.

Authors:  Andrea Molckovsky; Yolanda Madarnas
Journal:  Breast Cancer Res Treat       Date:  2007-05-26       Impact factor: 4.872

5.  Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG).

Authors:  B C Pestalozzi; D Zahrieh; K N Price; S B Holmberg; J Lindtner; J Collins; D Crivellari; M F Fey; E Murray; O Pagani; E Simoncini; M Castiglione-Gertsch; R D Gelber; A S Coates; A Goldhirsch
Journal:  Ann Oncol       Date:  2006-04-07       Impact factor: 32.976

6.  Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System.

Authors:  Jill S Barnholtz-Sloan; Andrew E Sloan; Faith G Davis; Fawn D Vigneau; Ping Lai; Raymond E Sawaya
Journal:  J Clin Oncol       Date:  2004-07-15       Impact factor: 44.544

7.  Phase II randomized trial of temozolomide and concurrent radiotherapy in patients with brain metastases.

Authors:  D Antonadou; M Paraskevaidis; G Sarris; N Coliarakis; I Economou; P Karageorgis; N Throuvalas
Journal:  J Clin Oncol       Date:  2002-09-01       Impact factor: 44.544

8.  Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial.

Authors:  David W Andrews; Charles B Scott; Paul W Sperduto; Adam E Flanders; Laurie E Gaspar; Michael C Schell; Maria Werner-Wasik; William Demas; Janice Ryu; Jean-Paul Bahary; Luis Souhami; Marvin Rotman; Minesh P Mehta; Walter J Curran
Journal:  Lancet       Date:  2004-05-22       Impact factor: 79.321

Review 9.  Radiotherapy and radiosensitizers in the treatment of glioblastoma multiforme.

Authors:  Julie E Chang; Deepak Khuntia; H Ian Robins; Minesh P Mehta
Journal:  Clin Adv Hematol Oncol       Date:  2007-11

10.  Breast cancer subtypes and survival in patients with brain metastases.

Authors:  Byung-Ho Nam; Sun Young Kim; Hye-Sook Han; Youngmee Kwon; Keun Seok Lee; Tae Hyun Kim; Jungsil Ro
Journal:  Breast Cancer Res       Date:  2008-02-28       Impact factor: 6.466

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.