W Qu1, Z-J Zhu2, L-Y Sun1, L Wei1, Y Liu1, Z-G Zeng1. 1. Liver Transplantation Section, Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing, China. 2. Liver Transplantation Section, Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Xicheng District, Beijing, China. Electronic address: fchzhuzhijun@hotmail.com.
Abstract
OBJECTIVE: The objectives of this study were to analyze the potential correlation between post-liver transplantation survival interval and CD4+ T-cell intracellular ATP (iATP) levels, and to describe the distribution of CD4+ T-cell iATP levels in liver transplant recipients. METHODS: This was a retrospective analysis of clinical data of 273 patients who underwent liver transplantation from July 2010 to October 2012 in our center and achieved long-term stable survival. CD4+ T-cell iATP level was detected using Cylex ImmuKnow assay. Post-liver transplantation survival was analyzed. RESULTS: CD4+ T-cell iATP level significantly differed among patients with different post-liver transplantation survival intervals. The peak CD4+ T-cell iATP levels typically occurred within the first 3 postoperative months. CONCLUSIONS: Post-liver transplantation survival interval is correlated with CD4+ T-cell iATP levels.
OBJECTIVE: The objectives of this study were to analyze the potential correlation between post-liver transplantation survival interval and CD4+ T-cell intracellular ATP (iATP) levels, and to describe the distribution of CD4+ T-cell iATP levels in liver transplant recipients. METHODS: This was a retrospective analysis of clinical data of 273 patients who underwent liver transplantation from July 2010 to October 2012 in our center and achieved long-term stable survival. CD4+ T-cell iATP level was detected using Cylex ImmuKnow assay. Post-liver transplantation survival was analyzed. RESULTS: CD4+ T-cell iATP level significantly differed among patients with different post-liver transplantation survival intervals. The peak CD4+ T-cell iATP levels typically occurred within the first 3 postoperative months. CONCLUSIONS: Post-liver transplantation survival interval is correlated with CD4+ T-cell iATP levels.
Authors: Madhusudhanan Narasimhan; Lenin Mahimainathan; Andrew E Clark; Amena Usmani; Jing Cao; Ellen Araj; Fernando Torres; Ravi Sarode; Vaidehi Kaza; Chantale Lacelle; Alagarraju Muthukumar Journal: Vaccines (Basel) Date: 2021-06-30