Literature DB >> 28217755

Lymphadenectomy in elderly/high risk patients: should it be different?

Laura Ruspi1, Federica Galli1, Vincenzo Pappalardo1, Davide Inversini1, Francesco Martignoni1, Luigi Boni1, Gianlorenzo Dionigi1, Stefano Rausei1.   

Abstract

The global aging of population will lead a greater number of elderly patients to undergo surgical procedure in a near future. Concerning gastric cancer, the impact of lymphadenectomy on survival has been demonstrated in RCTs, and extended lymphadenectomy is now considered as gold standard of treatment in non-early tumors. However, the role of age as a prognostic factor and the benefit of extended surgery in elderly/high-risk patients are not clearly defined yet. From our revision of literature, it seems that surgery for gastric cancer may have a further tailorization, considering not only the stage of disease, but also patients' age and comorbidities.

Entities:  

Keywords:  Lymphadenectomy; elderly/high risk patients; gastric cancer surgery; perioperative morbidity

Year:  2017        PMID： 28217755      PMCID： PMC5313282          DOI： 10.21037/tgh.2016.12.07

Source DB:  PubMed          Journal:  Transl Gastroenterol Hepatol        ISSN： 2415-1289


  42 in total

1.  Effect of age on prognosis in patients with gastric cancer.

Authors:  Hiroaki Saito; Tomohiro Osaki; Daiki Murakami; Teruhisa Sakamoto; Shingo Kanaji; Shigeru Tatebe; Shunichi Tsujitani; Masahide Ikeguchi
Journal:  ANZ J Surg       Date:  2006-06       Impact factor: 1.872

2.  Nodal dissection for patients with gastric cancer: a randomised controlled trial.

Authors:  Chew-Wun Wu; Chao A Hsiung; Su-Shun Lo; Mao-Chin Hsieh; Jen-Hao Chen; Anna Fen-Yau Li; Wing-Yiu Lui; Jacqueline Whang-Peng
Journal:  Lancet Oncol       Date:  2006-04       Impact factor: 41.316

Review 3.  The geriatric assessment.

Authors:  Bassem Elsawy; Kim E Higgins
Journal:  Am Fam Physician       Date:  2011-01-01       Impact factor: 3.292

4.  Japanese gastric cancer treatment guidelines 2010 (ver. 3).

Authors: 
Journal:  Gastric Cancer       Date:  2011-06       Impact factor: 7.370

5.  The outcome of surgical treatment for gastric carcinoma in the elderly.

Authors:  H Katai; M Sasako; T Sano; K Maruyama
Journal:  Jpn J Clin Oncol       Date:  1998-02       Impact factor: 3.019

6.  Estimation of Physiologic Ability and Surgical Stress (E-PASS) as a new prediction scoring system for postoperative morbidity and mortality following elective gastrointestinal surgery.

Authors:  Y Haga; S Ikei; M Ogawa
Journal:  Surg Today       Date:  1999       Impact factor: 2.549

7.  Comparison of surgical outcomes of gastric cancer in elderly and middle-aged patients.

Authors:  Chikara Kunisaki; Hirotoshi Akiyama; Masato Nomura; Goro Matsuda; Yuichi Otsuka; Hidetaka Andrew Ono; Hiroshi Shimada
Journal:  Am J Surg       Date:  2006-02       Impact factor: 2.565

8.  Surgery of gastric cancer and esophageal cancer: Does age matter?

Authors:  Henrik Nienhueser; Romy Kunzmann; Leila Sisic; Susanne Blank; Moritz J Strowitzk; Thomas Bruckner; Dirk Jäger; Wilko Weichert; Alexis Ulrich; Markus W Büchler; Katja Ott; Thomas Schmidt
Journal:  J Surg Oncol       Date:  2015-08-25       Impact factor: 3.454

9.  Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. Surgical Co-operative Group.

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Journal:  Br J Cancer       Date:  1999-03       Impact factor: 7.640

10.  Clinicopathological characteristics of gastric cancer in the elderly.

Authors:  K Kitamura; T Yamaguchi; H Taniguchi; A Hagiwara; T Yamane; K Sawai; T Takahashi
Journal:  Br J Cancer       Date:  1996-03       Impact factor: 7.640
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  5 in total

1.  Prognosis of elderly gastric cancer patients after surgery: a nomogram to predict survival.

Authors:  Michela Roberto; Andrea Botticelli; Lidia Strigari; Michele Ghidini; Concetta Elisa Onesti; Margherita Ratti; Ilaria Benzoni; Claudio Pizzo; Rosa Falcone; Daniele Lomiento; Bianca Maria Donida; Luigi Totaro; Federica Mazzuca; Paolo Marchetti
Journal:  Med Oncol       Date:  2018-06-19       Impact factor: 3.064

2.  Return to Intended Oncologic Treatment (RIOT) in Resected Gastric Cancer Patients.

Authors:  Marcus Fernando Kodama Pertille Ramos; Tiago Biachi de Castria; Marina Alessandra Pereira; Andre Roncon Dias; Fernanda Fronzoni Antonacio; Bruno Zilberstein; Paulo Marcelo Gehm Hoff; Ulysses Ribeiro; Ivan Cecconello
Journal:  J Gastrointest Surg       Date:  2019-11-19       Impact factor: 3.452

3.  Is it safe to perform gastrectomy in gastric cancer patients aged 80 or older?: A meta-analysis and systematic review.

Authors:  Yixin Xu; Yibo Wang; Cheng Xi; Nianyuan Ye; Xuezhong Xu
Journal:  Medicine (Baltimore)       Date:  2019-06       Impact factor: 1.817

4.  Clinical significance of neutrophil-to-lymphocyte ratio as a predictor of lymph node metastasis in gastric cancer.

Authors:  Toshiyuki Kosuga; Tomoki Konishi; Takeshi Kubota; Katsutoshi Shoda; Hirotaka Konishi; Atsushi Shiozaki; Kazuma Okamoto; Hitoshi Fujiwara; Michihiro Kudou; Tomohiro Arita; Ryo Morimura; Yasutoshi Murayama; Yoshiaki Kuriu; Hisashi Ikoma; Masayoshi Nakanishi; Eigo Otsuji
Journal:  BMC Cancer       Date:  2019-12-05       Impact factor: 4.430

5.  Optimal treatment for elderly patients with resectable proximal gastric carcinoma: a real world study based on National Cancer Database.

Authors:  Xuefei Wang; Junjie Zhao; Mark Fairweather; Tingsong Yang; Yihong Sun; Jiping Wang
Journal:  BMC Cancer       Date:  2019-11-09       Impact factor: 4.430
  5 in total

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