Physical characterization of the genome of a cattle isolate of capripoxvirus.

HindIII, Pstl, Aval, and SalI site maps have been determined for the genome of a cattle isolate of capripoxvirus, KC-1. The length of the genome was estimated, by summation of the lengths of individual HindIII fragments, to be 145.6 kb, and the genome was shown to possess terminally repeated regions 1.13-6.23 kb in length. The restriction site maps demonstrate that the genome of KC-1 does not possess a high degree of nucleotide sequence homology with the genomes of isolates of orthopoxvirus, parapoxvirus, leporipoxvirus, or African swine fever virus.