Literature DB >> 28216650

Gαq takes centre stage in multiple sclerosis pathogenesis.

Eric J Downer1.   

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Year:  2017        PMID： 28216650      PMCID： PMC5423092          DOI： 10.1038/cmi.2017.6

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


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  14 in total

Review 1.  G protein-coupled receptors as therapeutic targets for multiple sclerosis.

Authors:  Changsheng Du; Xin Xie
Journal:  Cell Res       Date:  2012-06-05       Impact factor: 25.617

2.  Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination.

Authors:  Rosetta Pedotti; Jason J DeVoss; Sawsan Youssef; Dennis Mitchell; Jochen Wedemeyer; Rami Madanat; Hideki Garren; Paulo Fontoura; Mindy Tsai; Stephen J Galli; Raymond A Sobel; Lawrence Steinman
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-07       Impact factor: 11.205

Review 3.  Pharmacological management of symptoms in multiple sclerosis: current approaches and future directions.

Authors:  Alan J Thompson; Ahmed T Toosy; Olga Ciccarelli
Journal:  Lancet Neurol       Date:  2010-12       Impact factor: 44.182

Review 4.  Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.

Authors:  Volker Brinkmann; Andreas Billich; Thomas Baumruker; Peter Heining; Robert Schmouder; Gordon Francis; Shreeram Aradhye; Pascale Burtin
Journal:  Nat Rev Drug Discov       Date:  2010-10-29       Impact factor: 84.694

Review 5.  Heterotrimeric G proteins and disease.

Authors:  Oyvind Melien
Journal:  Methods Mol Biol       Date:  2007

Review 6.  Mammalian G proteins and their cell type specific functions.

Authors:  Nina Wettschureck; Stefan Offermanns
Journal:  Physiol Rev       Date:  2005-10       Impact factor: 37.312

7.  Deficiency of the G protein Gαq ameliorates experimental autoimmune encephalomyelitis with impaired DC-derived IL-6 production and Th17 differentiation.

Authors:  Weiming Lai; Yingying Cai; Jinfeng Zhou; Shuai Chen; Chaoyan Qin; Cuixia Yang; Junling Liu; Xin Xie; Changsheng Du
Journal:  Cell Mol Immunol       Date:  2017-02-20       Impact factor: 11.530

8.  Antiasthmatic drugs targeting the cysteinyl leukotriene receptor 1 alleviate central nervous system inflammatory cell infiltration and pathogenesis of experimental autoimmune encephalomyelitis.

Authors:  Liefeng Wang; Changsheng Du; Jie Lv; Wei Wei; Ye Cui; Xin Xie
Journal:  J Immunol       Date:  2011-07-29       Impact factor: 5.422

9.  G[alpha]i2 and G[alpha]q expression change in pancreatic tissues and BN52021 effects in rats with severe acute pancreatitis.

Authors:  Shi-Hai Xia; Chun-Xiu Hu; Jin-miao Fang; Yao Di; Zhi-ling Zhao; Li-rong Liu
Journal:  Pancreas       Date:  2008-08       Impact factor: 3.327

10.  The Gαq/11 proteins contribute to T lymphocyte migration by promoting turnover of integrin LFA-1 through recycling.

Authors:  Lena Svensson; Paula Stanley; Frances Willenbrock; Nancy Hogg
Journal:  PLoS One       Date:  2012-06-11       Impact factor: 3.240
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