Literature DB >> 28215970

The role of exosomes in cancer metastasis.

Teresa Bernadette Steinbichler1, József Dudás1, Herbert Riechelmann1, Ira-Ida Skvortsova2.   

Abstract

Exosomes are small membrane vesicles with a size ranging from 40 to 100nm. They can serve as functional mediators in cell interaction leading to cancer metastasis. Metastasis is a complex multistep process of cancer cell invasion, survival in blood vessels, attachment to and colonization of the host organ. Exosomes influence every step of this cascade and can be targeted by oncological treatment. This review highlights the role of exosomes in the various steps of the metastatic cascade and how exosome dependent pathways can be targeted as therapeutic approach or used for liquid biopsies.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Cancer-associated fibroblasts; EMT; Organotropic metastasis; Premetastatic niche; Tumor derived exosomes

Mesh:

Year:  2017        PMID: 28215970     DOI: 10.1016/j.semcancer.2017.02.006

Source DB:  PubMed          Journal:  Semin Cancer Biol        ISSN: 1044-579X            Impact factor:   15.707


  121 in total

Review 1.  The functional role of exosome in hepatocellular carcinoma.

Authors:  Hongyu Liu; Baoguo Li
Journal:  J Cancer Res Clin Oncol       Date:  2018-07-30       Impact factor: 4.553

Review 2.  Ceramide and Exosomes: A Novel Target in Cancer Biology and Therapy.

Authors:  Ahmed Elsherbini; Erhard Bieberich
Journal:  Adv Cancer Res       Date:  2018-06-09       Impact factor: 6.242

Review 3.  Exosomes: from carcinogenesis and metastasis to diagnosis and treatment of gastric cancer.

Authors:  Houman Kahroba; Mohammad Saeid Hejazi; Nasser Samadi
Journal:  Cell Mol Life Sci       Date:  2019-02-08       Impact factor: 9.261

Review 4.  Chemotherapy-induced metastasis: mechanisms and translational opportunities.

Authors:  George S Karagiannis; John S Condeelis; Maja H Oktay
Journal:  Clin Exp Metastasis       Date:  2018-01-06       Impact factor: 5.150

5.  Cancer Cell Derived Small Extracellular Vesicles Contribute to Recipient Cell Metastasis Through Promoting HGF/c-Met Pathway.

Authors:  Zhi Qiao; Yan Zhang; Maolin Ge; Sha Liu; Xiaoteng Jiang; Zhi Shang; Han Liu; Chengxi Cao; Hua Xiao
Journal:  Mol Cell Proteomics       Date:  2019-06-13       Impact factor: 5.911

Review 6.  Current Progress in Tendon and Ligament Tissue Engineering.

Authors:  Wei Lee Lim; Ling Ling Liau; Min Hwei Ng; Shiplu Roy Chowdhury; Jia Xian Law
Journal:  Tissue Eng Regen Med       Date:  2019-06-26       Impact factor: 4.169

Review 7.  Modulating secreted components of tumor microenvironment: A masterstroke in tumor therapeutics.

Authors:  Himadri Patel; Pritish Nilendu; Devashree Jahagirdar; Jayanta K Pal; Nilesh Kumar Sharma
Journal:  Cancer Biol Ther       Date:  2017-12-08       Impact factor: 4.742

Review 8.  Tumor exosomes: a double-edged sword in cancer therapy.

Authors:  Wei Sun; Ju-Dong Luo; Hua Jiang; Dayue Darrel Duan
Journal:  Acta Pharmacol Sin       Date:  2018-03-15       Impact factor: 6.150

9.  Leukemia-derived exosomes and cytokines pave the way for entry into the brain.

Authors:  Ichiko Kinjyo; Denis Bragin; Rachel Grattan; Stuart S Winter; Bridget S Wilson
Journal:  J Leukoc Biol       Date:  2019-01-31       Impact factor: 4.962

10.  Macrophage-mediated transfer of cancer-derived components to stromal cells contributes to establishment of a pro-tumor microenvironment.

Authors:  Michinobu Umakoshi; So Takahashi; Go Itoh; Sei Kuriyama; Yuto Sasaki; Kazuyoshi Yanagihara; Masakazu Yashiro; Daichi Maeda; Akiteru Goto; Masamitsu Tanaka
Journal:  Oncogene       Date:  2018-11-20       Impact factor: 9.867

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