Literature DB >> 28215837

Antegrade sclerotherapy in adolescent varicocele patients.

D J B Keene1, R M Cervellione2.   

Abstract

INTRODUCTION: In the 1970s, Tauber described the antegrade sclerotherapy technique to treat varicoceles, and reported a 10% recurrence rate. The present study aimed to evaluate paediatric success rates and the effect of modifications to the surgical technique.
METHODS: A prospective study was performed of all adolescent patients undergoing antegrade sclerotherapy surgery. Each patient had an idiopathic varicocele with spontaneous venous reflux on Doppler examination, and underwent cannulation of a pampiniform plexus vein via a scrotal incision under general anaesthetic. Aethoxysklerol® 3% (2 ml/kg) maximum 3 ml was injected into the pampiniform plexus vein under fluoroscopic monitoring. Success was assessed by clinical examination and Doppler ultrasound 3, 6 and 9 months after surgery. Data were presented as median (interquartile range). Patients were split into three groups: Group A - liquid sclerotherapy with Y connector; Group B - liquid sclerotherapy direct to cannula; and Group C - foam sclerotherapy direct to cannula. Fisher's exact test was used to compare the success rates in each group.
RESULTS: A total of 91 patients underwent antegrade sclerotherapy. The median age was 14.8 years (range 13.7-15.5). Eleven persistent varicoceles occurred and were diagnosed by Doppler ultrasound. The success rate of surgery was 58% in Group A, 90% in Group B and 96% in Group C. Success was significantly higher in Group B and Group C compared with Group A. No testicular atrophy occurred; two wound infections, two haematomas and one hydrocele were recorded (Table).
CONCLUSION: Introduction of antegrade sclerotherapy in the adolescent population resulted in a safe and cost-effective method for the management of adolescent varicocele. Several modifications to the technique have been introduced to achieve a high success rate (96%) with minimal complications. Published by Elsevier Ltd.

Entities:  

Keywords:  Adolescent; Antegrade sclerotherapy; Varicocele

Mesh:

Year:  2017        PMID: 28215837     DOI: 10.1016/j.jpurol.2016.12.018

Source DB:  PubMed          Journal:  J Pediatr Urol        ISSN: 1477-5131            Impact factor:   1.830


  2 in total

Review 1.  Best practice in the diagnosis and treatment of varicocele in children and adolescents.

Authors:  Matthew R Macey; Ryan C Owen; Sherry S Ross; R Matthew Coward
Journal:  Ther Adv Urol       Date:  2018-06-22

Review 2.  [Varicocele in children and adolescents-conservative vs. surgical treatment?]

Authors:  T Yiakoumos; T Kälble
Journal:  Urologe A       Date:  2020-03       Impact factor: 0.639

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.