Shigekazu Ukawa1, Akiko Tamakoshi2, Hiroshi Yatsuya3, Kazumasa Yamagishi4, Masahiko Ando5, Hiroyasu Iso6. 1. Department of Public Health, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan. 2. Department of Public Health, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo, Hokkaido, 060-0812, Japan. tamaa@med.hokudai.ac.jp. 3. Department of Public Health, Fujita Health University, Aichi, Japan. 4. Department of Public Health Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan. 5. Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Aichi, Japan. 6. Public Health, Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine, Osaka, Japan.
Abstract
OBJECTIVES: To elucidate the association between passive smoking at home and chronic obstructive pulmonary disease (COPD) mortality via a large-scale nationwide cohort study in Japan. METHODS: Never smokers (n = 34,604) aged 40-79 years at baseline (1988-1990; 4884 men, 29,720 women) were included in the analysis. Passive smoking at home was measured based on self-reported frequency of weekly exposure to passive smoking at home. An inverse probability of treatment-weighted competing risk model was used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for COPD mortality. RESULTS: During a median follow-up of 16.4 years, 33 participants (10 men, 23 women) died of COPD. The HR for participants exposed to passive smoking at home ≤4 days per week or those who had almost daily exposure to passive smoking at home had a significantly increased risk of COPD mortality (HR 2.40, 95% CI 1.39-4.15, HR 2.88, 95% CI 1.68-4.93, respectively). CONCLUSIONS: The present findings suggest that avoiding passive smoking at home may be beneficial for preventing death due to COPD among never smokers.
OBJECTIVES: To elucidate the association between passive smoking at home and chronic obstructive pulmonary disease (COPD) mortality via a large-scale nationwide cohort study in Japan. METHODS: Never smokers (n = 34,604) aged 40-79 years at baseline (1988-1990; 4884 men, 29,720 women) were included in the analysis. Passive smoking at home was measured based on self-reported frequency of weekly exposure to passive smoking at home. An inverse probability of treatment-weighted competing risk model was used to calculate the hazard ratio (HR) and 95% confidence interval (CI) for COPD mortality. RESULTS: During a median follow-up of 16.4 years, 33 participants (10 men, 23 women) died of COPD. The HR for participants exposed to passive smoking at home ≤4 days per week or those who had almost daily exposure to passive smoking at home had a significantly increased risk of COPD mortality (HR 2.40, 95% CI 1.39-4.15, HR 2.88, 95% CI 1.68-4.93, respectively). CONCLUSIONS: The present findings suggest that avoiding passive smoking at home may be beneficial for preventing death due to COPD among never smokers.
Authors: Stig Hagstad; Anders Bjerg; Linda Ekerljung; Helena Backman; Anne Lindberg; Eva Rönmark; Bo Lundbäck Journal: Chest Date: 2014-06 Impact factor: 9.410
Authors: Mark D Eisner; Nicholas Anthonisen; David Coultas; Nino Kuenzli; Rogelio Perez-Padilla; Dirkje Postma; Isabelle Romieu; Edwin K Silverman; John R Balmes Journal: Am J Respir Crit Care Med Date: 2010-09-01 Impact factor: 21.405
Authors: P Yin; C Q Jiang; K K Cheng; T H Lam; K H Lam; M R Miller; W S Zhang; G N Thomas; P Adab Journal: Lancet Date: 2007-09-01 Impact factor: 79.321
Authors: Marieke M van der Zalm; Cuno S P M Uiterwaal; Berry Wilbrink; Brita M de Jong; Theo J M Verheij; Jan L L Kimpen; Cornelis K van der Ent Journal: Pediatr Infect Dis J Date: 2009-06 Impact factor: 2.129
Authors: A McGarry Houghton; Pablo A Quintero; David L Perkins; Dale K Kobayashi; Diane G Kelley; Luiz A Marconcini; Robert P Mecham; Robert M Senior; Steven D Shapiro Journal: J Clin Invest Date: 2006-02-09 Impact factor: 14.808
Authors: James C Hogg; Fanny Chu; Soraya Utokaparch; Ryan Woods; W Mark Elliott; Liliana Buzatu; Ruben M Cherniack; Robert M Rogers; Frank C Sciurba; Harvey O Coxson; Peter D Paré Journal: N Engl J Med Date: 2004-06-24 Impact factor: 91.245
Authors: Mostafa Qorbani; Ramin Heshmat; Mohammad Reza Hashemi-Aghdam; Gita Shafiee; Mehdi Ebrahimi; Hanieh-Sadat Ejtahed; Mehdi Yaseri; Mohammad Esmaeil Motlagh; Roya Kelishadi Journal: BMC Public Health Date: 2022-03-29 Impact factor: 3.295