| Literature DB >> 28213466 |
Leon J Klunder1, Klaas Nico Faber2, Gerard Dijkstra2, Sven C D van IJzendoorn1.
Abstract
Intestinal epithelial cell polarity is instrumental to maintain epithelial homeostasis and balance communications between the gut lumen and bodily tissue, thereby controlling the defense against gastrointestinal pathogens and maintenance of immune tolerance to commensal bacteria. In this review, we highlight recent advances with regard to the molecular mechanisms of cell polarity-controlled epithelial homeostasis and immunity in the human intestine.Entities:
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Year: 2017 PMID: 28213466 PMCID: PMC5495056 DOI: 10.1101/cshperspect.a027888
Source DB: PubMed Journal: Cold Spring Harb Perspect Biol ISSN: 1943-0264 Impact factor: 10.005