Andrés Fernández1, Ana Solís1, Paloma Cañete1, Jimena Del Castillo1, Javier Urbano1, Angel Carrillo1, Jesús López-Herce2. 1. Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón de Madrid, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón Facultad de Medicina, Universidad Complutense de Madrid, Spain. 2. Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón de Madrid, Instituto de Investigación Sanitaria del Hospital Gregorio Marañón Facultad de Medicina, Universidad Complutense de Madrid, Spain. Electronic address: pielvi@hotmail.com.
Abstract
OBJECTIVE: to analyze the incidence of infection in children who have suffered an in-hospital cardiac arrest (CA) and the association with mortality. METHODS: A retrospective unicenter observational study on a prospective database with children between one month and 16 years old, who have suffered an in-hospital CA was performed. Clinical, analytical and monitorization data, treatment, mortality and cause of death were recorded. RESULTS: 57 children were studied (57.6% males). Recovery of spontaneous circulation (ROSC) was achieved in 50 children (87.7%) and 32 (59.3%) survived. After ROSC, 28 patients (56% of those who achieved ROSC) were diagnosed of infection. There were not significant differences in mortality between patients infected (42.9%) and uninfected (27.3%) p=0.374. Only one died in consequence of a sepsis with multiorganic failure. CONCLUSIONS: The frequency of infection in children after recovering of a cardiac arrest is high. There were no statistically significant differences in mortality between patients with and without infection after ROSC.
OBJECTIVE: to analyze the incidence of infection in children who have suffered an in-hospital cardiac arrest (CA) and the association with mortality. METHODS: A retrospective unicenter observational study on a prospective database with children between one month and 16 years old, who have suffered an in-hospital CA was performed. Clinical, analytical and monitorization data, treatment, mortality and cause of death were recorded. RESULTS: 57 children were studied (57.6% males). Recovery of spontaneous circulation (ROSC) was achieved in 50 children (87.7%) and 32 (59.3%) survived. After ROSC, 28 patients (56% of those who achieved ROSC) were diagnosed of infection. There were not significant differences in mortality between patients infected (42.9%) and uninfected (27.3%) p=0.374. Only one died in consequence of a sepsis with multiorganic failure. CONCLUSIONS: The frequency of infection in children after recovering of a cardiac arrest is high. There were no statistically significant differences in mortality between patients with and without infection after ROSC.
Authors: Kathleen L Meert; Ralph Delius; Beth S Slomine; James R Christensen; Kent Page; Richard Holubkov; J Michael Dean; Frank W Moler Journal: Ann Thorac Surg Date: 2018-12-14 Impact factor: 4.330