| Literature DB >> 2821257 |
G Palazzino1, L Cecchi, F Melani, V Colotta, G Filacchioni, C Martini, A Lucacchini.
Abstract
A series of 1,3-diarylpyrazolo[4,5-c]- and -[5,4-c]quinolin-4-ones were prepared and tested for their ability to displace [3H]flunitrazepam from bovine brain membranes. While the 1,3-diarylpyrazolo[4,5-c]quinoline derivatives showed affinity for the receptor site, their [5,4-c] isomers were devoid of binding activity.Entities:
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Year: 1987 PMID： 2821257 DOI： 10.1021/jm00393a009
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446