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Literature DB >> 28210825

Recovery of nail dystrophy potential new therapeutic indication of tofacitinib.

Jose A Jaller¹, Juan J Jaller², Antonio M Jaller¹, Juan J Jaller-Char², Sineida Berbert Ferreira³, Rachel Ferreira³, Morton Scheinberg⁴.

Abstract

Nail dystrophy is a heterogeneous skin condition and in some subtypes, is associated with autoimmune diseases in particular psoriasis and psoriatic arthritis. In this report, we show that tofacitinib, a novel therapy for rheumatoid arthritis, appears to be beneficial in patients with nail disease refractory to other conventional modes of therapy.

Entities: Chemical Disease Species

Keywords: Janus kinase; Nail dystrophy; Tofacitinib

Mesh：

Substances：

Year: 2017 PMID： 28210825 DOI： 10.1007/s10067-017-3574-0

Source DB: PubMed Journal: Clin Rheumatol ISSN： 0770-3198 Impact factor: 2.980

12 in total

1. Tofacitinib Citrate for the Treatment of Nail Dystrophy Associated With Alopecia Universalis.

Authors: Arjun Dhayalan; Brett A King
Journal: JAMA Dermatol Date: 2016-04 Impact factor: 10.282

Review 2. Tofacitinib, an Oral Janus Kinase Inhibitor: Perspectives in Dermatology.

Authors: Kresimir Kostovic; Sandra J Gulin; Zrinka B Mokos; Romana Ceovic
Journal: Curr Med Chem Date: 2017-05-31 Impact factor: 4.530

Review 3. JAK/STAT Signal Transduction: Promising Attractive Targets for Immune, Inflammatory and Hematopoietic Diseases.

Authors: Qianwen Gao; Xuewu Liang; Abdul Sami Shaikh; Jie Zang; Wenfang Xu; Yingjie Zhang
Journal: Curr Drug Targets Date: 2018 Impact factor: 3.465

1. Brazilian Experience of the Treatment of Alopecia Universalis with the Novel Antirheumatic Therapy Tofacitinib: A Case Series.

Authors: Morton Scheinberg; Regina Adalva de Lucena Couto Océa; Boris Afonso Cruz; Sineida Berbert Ferreira
Journal: Rheumatol Ther Date: 2017-07-28

2. Recovery of Alopecia Universalis with Associated Nail Dystrophy Treated with Tofacitinib: A 6-year-old Child's Case Report.

Authors: Vineet Dube
Journal: Int J Trichology Date: 2021-11-22

2 in total

Recovery of nail dystrophy potential new therapeutic indication of tofacitinib.

1. Tofacitinib Citrate for the Treatment of Nail Dystrophy Associated With Alopecia Universalis.

Review 2. Tofacitinib, an Oral Janus Kinase Inhibitor: Perspectives in Dermatology.

Review 3. JAK/STAT Signal Transduction: Promising Attractive Targets for Immune, Inflammatory and Hematopoietic Diseases.

4. Reversal of Alopecia Universalis by Tofacitinib: A Case Report.

5. Killing two birds with one stone: oral tofacitinib reverses alopecia universalis in a patient with plaque psoriasis.

Review 6. Janus kinase (JAK) inhibitors in the treatment of inflammatory and neoplastic diseases.

7. Tofacitinib for the treatment of severe alopecia areata and variants: A study of 90 patients.

8. JAK inhibitors: A broadening approach in rheumatoid arthritis.

9. Trachyonychia associated with alopecia areata: a clinical and pathologic study.

10. Efficacy of tofacitinib in patients with rheumatoid arthritis stratified by background methotrexate dose group.

1. Brazilian Experience of the Treatment of Alopecia Universalis with the Novel Antirheumatic Therapy Tofacitinib: A Case Series.

2. Recovery of Alopecia Universalis with Associated Nail Dystrophy Treated with Tofacitinib: A 6-year-old Child's Case Report.