Takahide Arai1, Thierry Lefèvre2, Thomas Hovasse1, Marie-Claude Morice1, Mauro Romano1, Hakim Benamer1, Philippe Garot1, Kentaro Hayashida3, Erik Bouvier1, Bernard Chevalier1. 1. Ramsay Générale de Santé, Institut Cardiovasculaire Paris Sud, Hôpital Privé Jacques Cartier, Massy, France. 2. Ramsay Générale de Santé, Institut Cardiovasculaire Paris Sud, Hôpital Privé Jacques Cartier, Massy, France. Electronic address: t.lefevre@angio-icps.com. 3. Ramsay Générale de Santé, Institut Cardiovasculaire Paris Sud, Hôpital Privé Jacques Cartier, Massy, France; Department of Cardiology, Keio University School of Medicine, Tokyo, Japan.
Abstract
BACKGROUND: There are currently only limited data focusing on transcatheter aortic valve implantation (TAVI) for bicuspid aortic valves (BAV) patients using the Edwards SAPIEN (Irvine, CA, USA) 3 (S3) valve. The aim of this study was to evaluate the feasibility and efficacy of TAVI using the S3 in patients with BAV. METHODS: A total of 153 TAVI cases performed with the S3 were included. BAV was detected by multidetector computed tomography (MDCT) in 10 (7%) patients. The other patients had tricuspid aortic valves (TAV). The BAV and TAV groups were compared. RESULTS: Patient age and logistic EuroSCORE were similar in the BAV and TAV groups. The calculated annulus average diameter (CAAD) by MDCT was significantly larger in the BAV group (26.5mm vs 23.7mm, p=0.036) as was the annular area by MDCT (562mm2 vs 446mm2, p=0.033). On the other hand, the valve diameter/CAAD ratio was significantly lower in the BAV group (1.01 vs 1.06, p=0.010) as was the annular area oversizing percentage (3% vs 11%, p=0.033). There were no significant differences between the two groups regarding the frequency of paravalvular aortic leakage (PVL) ≥2 (0% vs 6%, p=0.492) and the 30-day mortality rate (0% vs 1%, p=0.799). CONCLUSIONS: Although TAVI for BAV tended to be carried out with a less oversized valve compared to TAVI for TAV, the frequency of post-procedural PVL ≥2 was similarly low in the two groups. TAVI using the S3 in patients with BAV seems to be feasible.
BACKGROUND: There are currently only limited data focusing on transcatheter aortic valve implantation (TAVI) for bicuspid aortic valves (BAV) patients using the Edwards SAPIEN (Irvine, CA, USA) 3 (S3) valve. The aim of this study was to evaluate the feasibility and efficacy of TAVI using the S3 in patients with BAV. METHODS: A total of 153 TAVI cases performed with the S3 were included. BAV was detected by multidetector computed tomography (MDCT) in 10 (7%) patients. The other patients had tricuspid aortic valves (TAV). The BAV and TAV groups were compared. RESULTS:Patient age and logistic EuroSCORE were similar in the BAV and TAV groups. The calculated annulus average diameter (CAAD) by MDCT was significantly larger in the BAV group (26.5mm vs 23.7mm, p=0.036) as was the annular area by MDCT (562mm2 vs 446mm2, p=0.033). On the other hand, the valve diameter/CAAD ratio was significantly lower in the BAV group (1.01 vs 1.06, p=0.010) as was the annular area oversizing percentage (3% vs 11%, p=0.033). There were no significant differences between the two groups regarding the frequency of paravalvular aortic leakage (PVL) ≥2 (0% vs 6%, p=0.492) and the 30-day mortality rate (0% vs 1%, p=0.799). CONCLUSIONS: Although TAVI for BAV tended to be carried out with a less oversized valve compared to TAVI for TAV, the frequency of post-procedural PVL ≥2 was similarly low in the two groups. TAVI using the S3 in patients with BAV seems to be feasible.
Authors: Salvatore Pasta; Stefano Cannata; Giovanni Gentile; Marzio Di Giuseppe; Federica Cosentino; Francesca Pasta; Valentina Agnese; Diego Bellavia; Giuseppe M Raffa; Michele Pilato; Caterina Gandolfo Journal: Med Biol Eng Comput Date: 2020-02-06 Impact factor: 2.602
Authors: Daniel Blackman; Davide Gabbieri; Bruno García Del Blanco; Jörg Kempfert; Mika Laine; Julia Mascherbauer; Radoslaw Parma; Didier Tchétché Journal: Cardiol Ther Date: 2021-06-03