Literature DB >> 28207061

Health facility challenges to the provision of Option B+ in western Kenya: a qualitative study.

Anna Helova1, Eliud Akama2, Elizabeth A Bukusi2, Pamela Musoke1, Wafula Z Nalwa3, Thomas A Odeny2,4, Maricianah Onono2, Sydney A Spangler5, Janet M Turan1, Iris Wanga2, Lisa L Abuogi6.   

Abstract

Current WHO guidelines recommend lifelong antiretroviral therapy (ART) for all HIV-positive individuals, including pregnant and breastfeeding women (Option B+) in settings with generalized HIV epidemics. While Option B+ is scaled-up in Kenya, insufficient adherence and retention to care could undermine the expected positive impact of Option B+. To explore challenges to the provision of Option B+ at the health facility level, we conducted forty individual gender-matched in-depth interviews with HIV-positive pregnant/postpartum women and their male partners, and four focus groups with thirty health care providers at four health facilities in western Kenya between September-November 2014. Transcripts were coded with the Dedoose software using a coding framework based on the literature, topics from interview guides, and emerging themes from transcripts. Excerpts from broad codes were then fine-coded using an inductive approach. Three major themes emerged: 1) Option B+ specific challenges (same-day initiation into treatment, health care providers unconvinced of the benefits of Option B+, insufficient training); 2) facility resource constraints (staff and drug shortages, long queues, space limitations); and 3) lack of client-friendly services (scolding of patients, inconvenient operating hours, lack of integration of services, administrative requirements). This study highlights important challenges at the health facility level related to Option B+ rollout in western Kenya. Addressing these specific challenges may increase linkage, retention and adherence to life-long ART treatment for pregnant HIV-positive women in Kenya, contribute towards elimination of mother-to-child HIV transmission, and improve maternal and child outcomes.

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Year:  2017        PMID: 28207061      PMCID: PMC5886182          DOI: 10.1093/heapol/czw122

Source DB:  PubMed          Journal:  Health Policy Plan        ISSN: 0268-1080            Impact factor:   3.344


  23 in total

1.  A qualitative analysis of the barriers and facilitators to receiving care in a prevention of mother-to-child program in Nkhoma, Malawi.

Authors:  Ngozi D Iroezi; Deborah Mindry; Paul Kawale; Grace Chikowi; Perry A Jansen; Risa M Hoffman
Journal:  Afr J Reprod Health       Date:  2013-12

2.  Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection.

Authors:  Jens D Lundgren; Abdel G Babiker; Fred Gordin; Sean Emery; Birgit Grund; Shweta Sharma; Anchalee Avihingsanon; David A Cooper; Gerd Fätkenheuer; Josep M Llibre; Jean-Michel Molina; Paula Munderi; Mauro Schechter; Robin Wood; Karin L Klingman; Simon Collins; H Clifford Lane; Andrew N Phillips; James D Neaton
Journal:  N Engl J Med       Date:  2015-07-20       Impact factor: 91.245

3.  The costs and benefits of Option B+ for the prevention of mother-to-child transmission of HIV.

Authors:  Chaitra Gopalappa; John Stover; Nathan Shaffer; Mary Mahy
Journal:  AIDS       Date:  2014-01       Impact factor: 4.177

4.  Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.

Authors:  Nicholas J Kassebaum; Amelia Bertozzi-Villa; Megan S Coggeshall; Katya A Shackelford; Caitlyn Steiner; Kyle R Heuton; Diego Gonzalez-Medina; Ryan Barber; Chantal Huynh; Daniel Dicker; Tara Templin; Timothy M Wolock; Ayse Abbasoglu Ozgoren; Foad Abd-Allah; Semaw Ferede Abera; Ibrahim Abubakar; Tom Achoki; Ademola Adelekan; Zanfina Ademi; Arsène Kouablan Adou; José C Adsuar; Emilie E Agardh; Dickens Akena; Deena Alasfoor; Zewdie Aderaw Alemu; Rafael Alfonso-Cristancho; Samia Alhabib; Raghib Ali; Mazin J Al Kahbouri; François Alla; Peter J Allen; Mohammad A AlMazroa; Ubai Alsharif; Elena Alvarez; Nelson Alvis-Guzmán; Adansi A Amankwaa; Azmeraw T Amare; Hassan Amini; Walid Ammar; Carl A T Antonio; Palwasha Anwari; Johan Arnlöv; Valentina S Arsic Arsenijevic; Ali Artaman; Majed Masoud Asad; Rana J Asghar; Reza Assadi; Lydia S Atkins; Alaa Badawi; Kalpana Balakrishnan; Arindam Basu; Sanjay Basu; Justin Beardsley; Neeraj Bedi; Tolesa Bekele; Michelle L Bell; Eduardo Bernabe; Tariku J Beyene; Zulfiqar Bhutta; Aref Bin Abdulhak; Jed D Blore; Berrak Bora Basara; Dipan Bose; Nicholas Breitborde; Rosario Cárdenas; Carlos A Castañeda-Orjuela; Ruben Estanislao Castro; Ferrán Catalá-López; Alanur Cavlin; Jung-Chen Chang; Xuan Che; Costas A Christophi; Sumeet S Chugh; Massimo Cirillo; Samantha M Colquhoun; Leslie Trumbull Cooper; Cyrus Cooper; Iuri da Costa Leite; Lalit Dandona; Rakhi Dandona; Adrian Davis; Anand Dayama; Louisa Degenhardt; Diego De Leo; Borja del Pozo-Cruz; Kebede Deribe; Muluken Dessalegn; Gabrielle A deVeber; Samath D Dharmaratne; Uğur Dilmen; Eric L Ding; Rob E Dorrington; Tim R Driscoll; Sergei Petrovich Ermakov; Alireza Esteghamati; Emerito Jose A Faraon; Farshad Farzadfar; Manuela Mendonca Felicio; Seyed-Mohammad Fereshtehnejad; Graça Maria Ferreira de Lima; Mohammad H Forouzanfar; Elisabeth B França; Lynne Gaffikin; Ketevan Gambashidze; Fortuné Gbètoho Gankpé; Ana C Garcia; Johanna M Geleijnse; Katherine B Gibney; Maurice Giroud; Elizabeth L Glaser; Ketevan Goginashvili; Philimon Gona; Dinorah González-Castell; Atsushi Goto; Hebe N Gouda; Harish Chander Gugnani; Rahul Gupta; Rajeev Gupta; Nima Hafezi-Nejad; Randah Ribhi Hamadeh; Mouhanad Hammami; Graeme J Hankey; Hilda L Harb; Rasmus Havmoeller; Simon I Hay; Ileana B Heredia Pi; Hans W Hoek; H Dean Hosgood; Damian G Hoy; Abdullatif Husseini; Bulat T Idrisov; Kaire Innos; Manami Inoue; Kathryn H Jacobsen; Eiman Jahangir; Sun Ha Jee; Paul N Jensen; Vivekanand Jha; Guohong Jiang; Jost B Jonas; Knud Juel; Edmond Kato Kabagambe; Haidong Kan; Nadim E Karam; André Karch; Corine Kakizi Karema; Anil Kaul; Norito Kawakami; Konstantin Kazanjan; Dhruv S Kazi; Andrew H Kemp; Andre Pascal Kengne; Maia Kereselidze; Yousef Saleh Khader; Shams Eldin Ali Hassan Khalifa; Ejaz Ahmed Khan; Young-Ho Khang; Luke Knibbs; Yoshihiro Kokubo; Soewarta Kosen; Barthelemy Kuate Defo; Chanda Kulkarni; Veena S Kulkarni; G Anil Kumar; Kaushalendra Kumar; Ravi B Kumar; Gene Kwan; Taavi Lai; Ratilal Lalloo; Hilton Lam; Van C Lansingh; Anders Larsson; Jong-Tae Lee; James Leigh; Mall Leinsalu; Ricky Leung; Xiaohong Li; Yichong Li; Yongmei Li; Juan Liang; Xiaofeng Liang; Stephen S Lim; Hsien-Ho Lin; Steven E Lipshultz; Shiwei Liu; Yang Liu; Belinda K Lloyd; Stephanie J London; Paulo A Lotufo; Jixiang Ma; Stefan Ma; Vasco Manuel Pedro Machado; Nana Kwaku Mainoo; Marek Majdan; Christopher Chabila Mapoma; Wagner Marcenes; Melvin Barrientos Marzan; Amanda J Mason-Jones; Man Mohan Mehndiratta; Fabiola Mejia-Rodriguez; Ziad A Memish; Walter Mendoza; Ted R Miller; Edward J Mills; Ali H Mokdad; Glen Liddell Mola; Lorenzo Monasta; Jonathan de la Cruz Monis; Julio Cesar Montañez Hernandez; Ami R Moore; Maziar Moradi-Lakeh; Rintaro Mori; Ulrich O Mueller; Mitsuru Mukaigawara; Aliya Naheed; Kovin S Naidoo; Devina Nand; Vinay Nangia; Denis Nash; Chakib Nejjari; Robert G Nelson; Sudan Prasad Neupane; Charles R Newton; Marie Ng; Mark J Nieuwenhuijsen; Muhammad Imran Nisar; Sandra Nolte; Ole F Norheim; Luke Nyakarahuka; In-Hwan Oh; Takayoshi Ohkubo; Bolajoko O Olusanya; Saad B Omer; John Nelson Opio; Orish Ebere Orisakwe; Jeyaraj D Pandian; Christina Papachristou; Jae-Hyun Park; Angel J Paternina Caicedo; Scott B Patten; Vinod K Paul; Boris Igor Pavlin; Neil Pearce; David M Pereira; Konrad Pesudovs; Max Petzold; Dan Poenaru; Guilherme V Polanczyk; Suzanne Polinder; Dan Pope; Farshad Pourmalek; Dima Qato; D Alex Quistberg; Anwar Rafay; Kazem Rahimi; Vafa Rahimi-Movaghar; Sajjad ur Rahman; Murugesan Raju; Saleem M Rana; Amany Refaat; Luca Ronfani; Nobhojit Roy; Tania Georgina Sánchez Pimienta; Mohammad Ali Sahraian; Joshua A Salomon; Uchechukwu Sampson; Itamar S Santos; Monika Sawhney; Felix Sayinzoga; Ione J C Schneider; Austin Schumacher; David C Schwebel; Soraya Seedat; Sadaf G Sepanlou; Edson E Servan-Mori; Marina Shakh-Nazarova; Sara Sheikhbahaei; Kenji Shibuya; Hwashin Hyun Shin; Ivy Shiue; Inga Dora Sigfusdottir; Donald H Silberberg; Andrea P Silva; Jasvinder A Singh; Vegard Skirbekk; Karen Sliwa; Sergey S Soshnikov; Luciano A Sposato; Chandrashekhar T Sreeramareddy; Konstantinos Stroumpoulis; Lela Sturua; Bryan L Sykes; Karen M Tabb; Roberto Tchio Talongwa; Feng Tan; Carolina Maria Teixeira; Eric Yeboah Tenkorang; Abdullah Sulieman Terkawi; Andrew L Thorne-Lyman; David L Tirschwell; Jeffrey A Towbin; Bach X Tran; Miltiadis Tsilimbaris; Uche S Uchendu; Kingsley N Ukwaja; Eduardo A Undurraga; Selen Begüm Uzun; Andrew J Vallely; Coen H van Gool; Tommi J Vasankari; Monica S Vavilala; N Venketasubramanian; Salvador Villalpando; Francesco S Violante; Vasiliy Victorovich Vlassov; Theo Vos; Stephen Waller; Haidong Wang; Linhong Wang; XiaoRong Wang; Yanping Wang; Scott Weichenthal; Elisabete Weiderpass; Robert G Weintraub; Ronny Westerman; James D Wilkinson; Solomon Meseret Woldeyohannes; John Q Wong; Muluemebet Abera Wordofa; Gelin Xu; Yang C Yang; Yuichiro Yano; Gokalp Kadri Yentur; Paul Yip; Naohiro Yonemoto; Seok-Jun Yoon; Mustafa Z Younis; Chuanhua Yu; Kim Yun Jin; Maysaa El Sayed Zaki; Yong Zhao; Yingfeng Zheng; Maigeng Zhou; Jun Zhu; Xiao Nong Zou; Alan D Lopez; Mohsen Naghavi; Christopher J L Murray; Rafael Lozano
Journal:  Lancet       Date:  2014-05-02       Impact factor: 79.321

5.  Implementation and Operational Research: Barriers and Facilitators to Combined ART Initiation in Pregnant Women With HIV: Lessons Learnt From a PMTCT B+ Pilot Program in Swaziland.

Authors:  Lucy A Parker; Kiran Jobanputra; Velephi Okello; Mpumelelo Nhlangamandla; Sikhathele Mazibuko; Tatiana Kourline; Bernhard Kerschberger; Elias Pavlopoulos; Roger Teck
Journal:  J Acquir Immune Defic Syndr       Date:  2015-05-01       Impact factor: 3.731

6.  Progress Toward Eliminating Mother to Child Transmission of HIV in Kenya: Review of Treatment Guideline Uptake and Pediatric Transmission at Four Government Hospitals Between 2010 and 2012.

Authors:  Sarah Finocchario-Kessler; Kristine F Clark; Samoel Khamadi; Brad J Gautney; Vincent Okoth; Kathy Goggin
Journal:  AIDS Behav       Date:  2016-11

Review 7.  Lessons learned from early implementation of option B+: the Elizabeth Glaser Pediatric AIDS Foundation experience in 11 African countries.

Authors:  Mary Pat Kieffer; Meghan Mattingly; Anja Giphart; Roland van de Ven; Caspian Chouraya; Moses Walakira; Alexandre Boon; Silvia Mikusova; R J Simonds
Journal:  J Acquir Immune Defic Syndr       Date:  2014-12-01       Impact factor: 3.731

8.  Toward an understanding of disengagement from HIV treatment and care in sub-Saharan Africa: a qualitative study.

Authors:  Norma C Ware; Monique A Wyatt; Elvin H Geng; Sylvia F Kaaya; Oche O Agbaji; Winnie R Muyindike; Guerino Chalamilla; Patricia A Agaba
Journal:  PLoS Med       Date:  2013-01-08       Impact factor: 11.069

Review 9.  Barriers and facilitating factors to the uptake of antiretroviral drugs for prevention of mother-to-child transmission of HIV in sub-Saharan Africa: a systematic review.

Authors:  Annabelle Gourlay; Isolde Birdthistle; Gitau Mburu; Kate Iorpenda; Alison Wringe
Journal:  J Int AIDS Soc       Date:  2013-07-19       Impact factor: 5.396

Review 10.  Interventions to improve or facilitate linkage to or retention in pre-ART (HIV) care and initiation of ART in low- and middle-income settings--a systematic review.

Authors:  Darshini Govindasamy; Jamilah Meghij; Eyerusalem Kebede Negussi; Rachel Clare Baggaley; Nathan Ford; Katharina Kranzer
Journal:  J Int AIDS Soc       Date:  2014-08-01       Impact factor: 5.396

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  24 in total

1.  Stepped-Wedge Cluster Randomized Controlled Trial to Promote Option B+ Retention in Central Mozambique.

Authors:  James T Pfeiffer; Manuel Napúa; Bradley H Wagenaar; Falume Chale; Roxanne Hoek; Mark Micek; João Manuel; Cathy Michel; Jessica Greenberg Cowan; James F Cowan; Sarah Gimbel; Kenneth Sherr; Stephen Gloyd; Rachel R Chapman
Journal:  J Acquir Immune Defic Syndr       Date:  2017-11-01       Impact factor: 3.731

2.  Implementation of the 'Test and Treat' policy for newly diagnosed people living with HIV in Zimbabwe in 2017.

Authors:  A Rufu; V T S Chitimbire; C Nzou; C Timire; P Owiti; A D Harries; T Apollo
Journal:  Public Health Action       Date:  2018-09-21

3.  "This is My Life We are Talking About": Adaptive Strategies for HIV Care Retention and Treatment Adherence Among Postpartum Women Living with HIV in Cape Town, South Africa.

Authors:  Alison Z Weber; Jennifer A Pellowski; Kirsty Brittain; Abigail Harrison; Tamsin K Phillips; Allison Zerbe; Elaine J Abrams; Landon Myer
Journal:  Matern Child Health J       Date:  2020-12

4.  A group randomized trial using an appointment system to improve adherence to ART at reproductive and child health clinics implementing Option B+ in Tanzania.

Authors:  Dennis Ross-Degnan; John Chalker; Jafary Liana; Mwikemo Deborah Kajoka; Richard Valimba; Suleiman Kimatta; Angel Dillip; Catherine Vialle-Valentin; Martha Embrey; Rachel Lieber; Keith Johnson
Journal:  PLoS One       Date:  2017-09-28       Impact factor: 3.240

5.  Job satisfaction and turnover intentions among health care staff providing services for prevention of mother-to-child transmission of HIV in Dar es Salaam, Tanzania.

Authors:  Helga Naburi; Phares Mujinja; Charles Kilewo; Nicola Orsini; Till Bärnighausen; Karim Manji; Gunnel Biberfeld; David Sando; Pascal Geldsetzer; Guerino Chalamila; Anna Mia Ekström
Journal:  Hum Resour Health       Date:  2017-09-06

6.  Differentiated models of care for postpartum women on antiretroviral therapy in Cape Town, South Africa: a cohort study.

Authors:  Landon Myer; Victoria Iyun; Allison Zerbe; Tamsin K Phillips; Kirsty Brittain; Elton Mukonda; Joanna Allerton; Cathy D Kalombo; Andile Nofemela; Elaine J Abrams
Journal:  J Int AIDS Soc       Date:  2017-07-21       Impact factor: 5.396

7.  Spatial-temporal trend for mother-to-child transmission of HIV up to infancy and during pre-Option B+ in western Kenya, 2007-13.

Authors:  Anthony Waruru; Thomas N O Achia; Hellen Muttai; Lucy Ng'ang'a; Emily Zielinski-Gutierrez; Boniface Ochanda; Abraham Katana; Peter W Young; James L Tobias; Peter Juma; Kevin M De Cock; Thorkild Tylleskär
Journal:  PeerJ       Date:  2018-03-13       Impact factor: 2.984

8.  Benefits and risks of rapid initiation of antiretroviral therapy.

Authors:  Nathan Ford; Chantal Migone; Alexandra Calmy; Bernhard Kerschberger; Steve Kanters; Sabin Nsanzimana; Edward J Mills; Graeme Meintjes; Marco Vitoria; Meg Doherty; Zara Shubber
Journal:  AIDS       Date:  2018-01-02       Impact factor: 4.177

9.  Maximizing adherence and retention for women living with HIV and their infants in Kenya (MOTIVATE! study): study protocol for a randomized controlled trial.

Authors:  Thomas A Odeny; Maricianah Onono; Kevin Owuor; Anna Helova; Iris Wanga; Elizabeth A Bukusi; Janet M Turan; Lisa L Abuogi
Journal:  Trials       Date:  2018-01-29       Impact factor: 2.279

10.  Barriers to maternal retention in HIV care in Ghana: key differences during pregnancy and the postpartum period.

Authors:  Kwame S Sakyi; Margaret Y Lartey; Caitlin E Kennedy; Julie A Dension; Luke C Mullany; Prince G Owusu; Emma Sacks; Emily A Hurley; Pamela J Surkan
Journal:  BMC Pregnancy Childbirth       Date:  2020-07-17       Impact factor: 3.007

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