Literature DB >> 28206679

Technical Note: Determination of individual thyroid clearance effective half-life with a common handheld electronic dosimeter.

Markus Fürstner1, Michael Hentschel1, Petar-Marko Spanjol1, George A Prenosil1, Sabine Weidner1, Thomas Krause1, Bernd Klaeser1.   

Abstract

PURPOSE: To determine the thyroid clearance effective half-life T with a common handheld electronic dosimeter (ED) in patients undergoing radioiodine treatment for hyperthyroidism.
METHODS: Dose rates from 12 inpatients were measured daily with an ED and with a clinical uptake counter. The ED was attached to the patient with two different setups, one using a cervical collar and another employing a neck strap. Estimation of T was performed by linear regression analysis of the log of both the ED and the uptake counter measurements versus time. The latter provided the reference data.
RESULTS: Based on repeated neck strap dose rate measurements, individual Ts were determined with clinically required accuracy. The mean difference from the reference method equaled to -0.09 ± 0.35 days.
CONCLUSIONS: Determination of individual T is feasible with a common handheld ED using the simple and easy to instruct neck strap measurement setup. This simple method complements stationary uptake counter measurements and thus may improve the accuracy of radioiodine treatment planning by adding an individual T for dose calculation.
© 2017 American Association of Physicists in Medicine.

Entities:  

Keywords:  effective half-life; electronic dosimeter; hyperthyroidism; radioiodine; thyroid

Mesh:

Substances:

Year:  2017        PMID: 28206679     DOI: 10.1002/mp.12161

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  2 in total

1.  In vitro evaluation of an iodine radionuclide dosimeter (IRD) for continuous patient monitoring.

Authors:  Sanaz Hariri Tabrizi; Meysam Ramezani; Seyed Amir Hossein Feghhi; Parham Geramifar
Journal:  Med Biol Eng Comput       Date:  2020-01-28       Impact factor: 2.602

2.  Prediction of thyroidal 131I effective half-life in patients with Graves' disease.

Authors:  Ruiguo Zhang; Guizhi Zhang; Renfei Wang; Jian Tan; Yajing He; Zhaowei Meng
Journal:  Oncotarget       Date:  2017-09-12
  2 in total

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