Iron(ii)-catalyzed sulfur directed C(sp3)-H bond amination/C-S cross coupling reaction.

An efficient iron(ii)-catalyzed sulfur directed C(sp3)-H bond amination/C-S cross coupling reaction has been developed. The reaction had high tolerance of functional groups under moderate conditions. The results of a deuterium labeling study and in situ ESI-MS experiments indicated that the reaction mechanism probably corresponds to a Fe(ii)/Fe(iii) catalytic cycle.