Literature DB >> 28197899

Erratum to: Test-retest analysis of a non-invasive method of quantifying [(11)C]-PBR28 binding in Alzheimer's disease.

Akshay Nair1, Mattia Veronese2, Xiaohui Xu3,4, Charles Curtis3,4, Federico Turkheimer2, Robert Howard5, Suzanne Reeves5.   

Abstract

Entities:  

Year:  2017        PMID: 28197899      PMCID: PMC5309185          DOI: 10.1186/s13550-017-0256-5

Source DB:  PubMed          Journal:  EJNMMI Res        ISSN: 2191-219X            Impact factor:   3.138


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Erratum

Following publication of the original article [1] the authors contacted the team with the request that some additional information be added to the article. Please see below for details: Additional Table: absolute variability Variability (VAR) presented in the main article represents mean variability between test and retest, not absolute variability as stated. The authors would like to apologise for this error. The absolute variability is presented in the table below has been calculated in the following manner: These analyses allow for easier comparison with other studies however do no alter the findings or discussion of the paper – SUV normalised to whole brain (SUVWB) shows the lowest variability in our cohort, with increased variability found in the unadjusted SUV and the SUV normalised to cerebellum. As compared to other test-retest studies discussed in the paper, the variability for SUV based methods remains favourable in this pilot cohort. These results should be validated in larger studies.
Raw SUVSUVWB SUVC
Frontal Lobe6.051.014.36
(2.45)(0.67)(4.84)
Parietal Lobe6.690.975.15
(2.33)(0.77)(5.10)
Temporal Lobe5.920.613.78
(3.13)(0.49)(4.92)
Occipital Lobe6.811.073.87
(2.83)(0.88)(3.79)
Hippocampus5.821.575.35
(1.95)(1.34)(6.50)
Parahippocam-pal cortex5.052.075.77
(3.78)(2.58)(7.96)
Posterior Cingulate6.581.895.92
(2.60)(1.33)(5.97)
Amygdala3.454.316.54
(4.50)(3.17)(8.56)
Cerebellum7.184.18
(7.84)(5.07)
Whole Brain6.09
(2.73)
Mean (SD)5.961.965.09
(3.41)(1.81)(5.95)
  1 in total

1.  Test-retest analysis of a non-invasive method of quantifying [(11)C]-PBR28 binding in Alzheimer's disease.

Authors:  Akshay Nair; Mattia Veronese; Xiaohui Xu; Charles Curtis; Federico Turkheimer; Robert Howard; Suzanne Reeves
Journal:  EJNMMI Res       Date:  2016-09-27       Impact factor: 3.138

  1 in total

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