Mark Sherer1, Jennie Ponsford, Amelia Hicks, Luis Leon-Novelo, Esther Ngan, Angelle M Sander. 1. TIRR Memorial Hermann, Houston, Texas (Drs Sherer and Sander); Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas (Drs Sherer and Sander); School of Psychological Sciences, Monash University and Epworth Hospital, Melbourne, Australia (Dr Ponsford and Ms Hicks); School of Public Health, University of Texas Health Science Center at Houston, Texas (Dr Leon-Novelo and Ms Ngan); Beth K. and Stuart C. Yudofsky Division of Neuropsychiatry, Department of Psychiatry, Baylor College of Medicine, Houston, Texas (Dr Sander); and Physical Medicine and Rehabilitation, Harris Health System, Houston, Texas (Dr Sander).
Abstract
OBJECTIVE: To (1) identify groupings of persons with traumatic brain injury (TBI) in the posthospital period in a cohort recruited in Australia; (2) compare groupings from the Australian cohort to groupings previously developed for a US cohort. SETTING: Rehabilitation centers in the US and Australia. PARTICIPANTS: A total of 170 persons with TBI from Australia and 504 persons with TBI from the United States. Participants were aged 18 to 64 years, greater than 6 months postinjury, had capacity to give consent, and had definitive contemporaneous medical evidence of TBI. DESIGN: Observational study. MAIN MEASURES: Cognitive tests-Wechsler Letter-Number Sequencing and Coding, Rey Auditory Verbal Learning Test, Trail Making Test, Verbal Fluency. Questionnaires-9 scales from the Traumatic Brain Injury Quality-of-Life system; Neurobehavioral Symptom Inventory; Economic Quality of Life, Family Assessment Device-General Functioning. Performance validity-Word Memory Test. RESULTS: Agreement in classification for the 2 samples was only moderate with 63.5% correctly classified and Cohen's κ = 0.53. A post hoc analysis placing all persons showing poor performance validity in the same group improved classification to 73% and Cohen's κ = 0.65 indicating substantial agreement. CONCLUSION: Results provided support for the patient groups developed for the US sample and indicate that these groupings largely replicated in a new cohort.
OBJECTIVE: To (1) identify groupings of persons with traumatic brain injury (TBI) in the posthospital period in a cohort recruited in Australia; (2) compare groupings from the Australian cohort to groupings previously developed for a US cohort. SETTING: Rehabilitation centers in the US and Australia. PARTICIPANTS: A total of 170 persons with TBI from Australia and 504 persons with TBI from the United States. Participants were aged 18 to 64 years, greater than 6 months postinjury, had capacity to give consent, and had definitive contemporaneous medical evidence of TBI. DESIGN: Observational study. MAIN MEASURES: Cognitive tests-Wechsler Letter-Number Sequencing and Coding, Rey Auditory Verbal Learning Test, Trail Making Test, Verbal Fluency. Questionnaires-9 scales from the Traumatic Brain Injury Quality-of-Life system; Neurobehavioral Symptom Inventory; Economic Quality of Life, Family Assessment Device-General Functioning. Performance validity-Word Memory Test. RESULTS: Agreement in classification for the 2 samples was only moderate with 63.5% correctly classified and Cohen's κ = 0.53. A post hoc analysis placing all persons showing poor performance validity in the same group improved classification to 73% and Cohen's κ = 0.65 indicating substantial agreement. CONCLUSION: Results provided support for the patient groups developed for the US sample and indicate that these groupings largely replicated in a new cohort.
Authors: Mark Sherer; Angelle M Sander; Jennie Ponsford; Leia Vos; Julia M P Poritz; Esther Ngan; Luis Leon Novelo Journal: J Int Neuropsychol Soc Date: 2020-05-27 Impact factor: 2.892