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Literature DB >> 28191695

Breast Cancer in Pregnancy: Avoiding Fetal Harm When Maternal Treatment Is Necessary.

Christina N Cordeiro¹, Mary L Gemignani².

Abstract

The management of breast cancer during pregnancy poses unique challenges and requires a multi-disciplinary approach. In this review, we discuss the treatment of breast cancer in pregnancy and recent updates regarding the safety of surgical and chemotherapeutic treatments, including both oncologic and fetal outcomes. The treatment of breast cancer during pregnancy mirrors that outside of pregnancy, with a few important differences dictated by the balance of maternal versus fetal health. Overall, surgical treatment, neo-adjuvant chemotherapy, and/or adjuvant chemotherapy are feasible in most women during pregnancy. Further research to determine the safety of these therapies in pregnancy-associated breast cancer is warranted.

Entities: Chemical Disease Gene Species

Keywords: breast cancer; chemotherapy; pregnancy

Mesh：

Substances：
Antineoplastic Agents

Year: 2017 PMID： 28191695 PMCID： PMC5408732 DOI： 10.1111/tbj.12780

Source DB: PubMed Journal: Breast J ISSN： 1075-122X Impact factor: 2.431

31 in total

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Authors: A P Ayyappan; S Kulkarni; P Crystal
Journal: Br J Radiol Date: 2010-03-24 Impact factor: 3.039

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Journal: J Clin Oncol Date: 2005-06-20 Impact factor: 44.544

3. Sentinel lymph node biopsy in pregnant women with breast cancer.

Authors: Adrienne B Gropper; Katherina Zabicki Calvillo; Laura Dominici; Susan Troyan; Esther Rhei; Katherine E Economy; Nadine M Tung; Lidia Schapira; Jane L Meisel; Ann H Partridge; Erica L Mayer
Journal: Ann Surg Oncol Date: 2014-04-23 Impact factor: 5.344

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Authors: Kristjan Skuli Asgeirsson
Journal: Acta Obstet Gynecol Scand Date: 2010-12-02 Impact factor: 3.636

5. Long-term cognitive and cardiac outcomes after prenatal exposure to chemotherapy in children aged 18 months or older: an observational study.

Authors: Frédéric Amant; Kristel Van Calsteren; Michael J Halaska; Mina Mhallem Gziri; Wei Hui; Lieven Lagae; Michèl A Willemsen; Livia Kapusta; Ben Van Calster; Heidi Wouters; Liesbeth Heyns; Sileny N Han; Viktor Tomek; Luc Mertens; Petronella B Ottevanger
Journal: Lancet Oncol Date: 2012-02-10 Impact factor: 41.316

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Authors: J Fajdić; N Gotovac; Z Hrgović; W J Fassbender
Journal: Adv Med Sci Date: 2008 Impact factor: 3.287

Review 7. Trastuzumab administration during pregnancy: a systematic review and meta-analysis.

Authors: Flora Zagouri; Theodoros N Sergentanis; Dimosthenis Chrysikos; Christos A Papadimitriou; Meletios-Athanassios Dimopoulos; Rupert Bartsch
Journal: Breast Cancer Res Treat Date: 2012-12-15 Impact factor: 4.872

8. Measurement of uterine radiation exposure from lymphoscintigraphy indicates safety of sentinel lymph node biopsy during pregnancy.

Authors: Philip M Spanheimer; Michael M Graham; Sonia L Sugg; Carol E H Scott-Conner; Ronald J Weigel
Journal: Ann Surg Oncol Date: 2009-03-07 Impact factor: 5.344

3. Clinical characteristics, pregnancy outcomes and ovarian function of pregnancy-associated breast cancer patients: a retrospective age-matched study.

Authors: Qiuyue Liao; Dongmei Deng; Qin Xie; Xiaoqin Gong; Xiaolin Meng; Yun Xia; Jihui Ai; Kezhen Li
Journal: BMC Cancer Date: 2022-02-07 Impact factor: 4.430

3 in total