Literature DB >> 28191478

Regulation of glycolysis in head and neck squamous cell carcinoma.

Dhruv Kumar1.   

Abstract

Glycolysis is highly upregulated in head and neck squamous cell carcinoma (HNSCC). HNSCC glycolysis is an important contributor to disease progression and decreases sensitivity to radiation or chemotherapy. Despite therapeutic advances, the survival rates for HNSCC patients remain low. Understanding glycolysis regulation in HNSCC will facilitate the development of effective therapeutic strategies for this disease. In this review, we will evaluate the regulation of altered HNSCC glycolysis and possible therapeutic approaches by targeting glycolytic pathways.

Entities:  

Keywords:  GLUT-1; HIF-1; HK-II and LDH-A; HNSCC; glycolysis; p53

Year:  2017        PMID： 28191478      PMCID： PMC5300767          DOI： 10.14304/surya.jpr.v5n1.4

Source DB:  PubMed          Journal:  Postdoc J        ISSN： 2328-9791


  120 in total

1.  On the origin of cancer cells.

Authors:  O WARBURG
Journal:  Science       Date:  1956-02-24       Impact factor: 47.728

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Authors:  Sheng-Jiao Li; Wei Guo; Guo-Xin Ren; Gang Huang; Tao Chen; Shao-Li Song
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5.  Enhanced response of human head and neck cancer xenograft tumors to cisplatin combined with 2-deoxy-D-glucose correlates with increased 18F-FDG uptake as determined by PET imaging.

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