Jinhua Zheng1, Xinglong Yang1, Yalan Chen1, Quanzhen Zhao1, Sijia Tian1, Hongyan Huang1, Yanming Xu2. 1. Department of Neurology, West China Hospital, Sichuan University, 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, People's Republic of China. 2. Department of Neurology, West China Hospital, Sichuan University, 37 Guo Xue Xiang, Chengdu, 610041, Sichuan, People's Republic of China. neuroxym999@163.com.
Abstract
PURPOSE: To compare the order of presentation of bladder and motor symptoms between multiple system atrophy phenotypes. METHODS: Medical records were retrospectively reviewed in 144 patients. RESULTS: Bladder symptoms occurred either before or within 12 months after onset of motor symptoms in significantly more patients with the cerebellar phenotype than the parkinsonian phenotype (80 vs. 53%, p = 0.003); similar results were observed for urinary incontinence (79 vs. 45%, p = 0.001). CONCLUSIONS: Urinary dysfunction is more likely to appear either before or shortly after motor symptoms in the cerebellar phenotype than in the parkinsonian phenotype.
PURPOSE: To compare the order of presentation of bladder and motor symptoms between multiple system atrophy phenotypes. METHODS: Medical records were retrospectively reviewed in 144 patients. RESULTS: Bladder symptoms occurred either before or within 12 months after onset of motor symptoms in significantly more patients with the cerebellar phenotype than the parkinsonian phenotype (80 vs. 53%, p = 0.003); similar results were observed for urinary incontinence (79 vs. 45%, p = 0.001). CONCLUSIONS:Urinary dysfunction is more likely to appear either before or shortly after motor symptoms in the cerebellar phenotype than in the parkinsonian phenotype.
Entities:
Keywords:
Autonomic dysfunction; Multiple system atrophy; Orthostatic hypotension; Urinary incontinence
Authors: Martin Köllensperger; Felix Geser; Jean-Pierre Ndayisaba; Sylvia Boesch; Klaus Seppi; Karen Ostergaard; Erik Dupont; A Cardozo; Eduardo Tolosa; Michael Abele; Thomas Klockgether; Farid Yekhlef; Francois Tison; Christine Daniels; Günther Deuschl; Miguel Coelho; Cristina Sampaio; Maria Bozi; Niall Quinn; Anette Schrag; Chris J Mathias; Clare Fowler; Christer F Nilsson; Håkan Widner; Nicole Schimke; Wolfgang Oertel; Francesca Del Sorbo; Alberto Albanese; Maria Teresa Pellecchia; Paolo Barone; Ruth Djaldetti; Carlo Colosimo; Giuseppe Meco; Antonio Gonzalez-Mandly; Jose Berciano; Tanya Gurevich; Nir Giladi; Monique Galitzky; Olivier Rascol; Christoph Kamm; Thomas Gasser; Uwe Siebert; Werner Poewe; Gregor K Wenning Journal: Mov Disord Date: 2010-11-15 Impact factor: 10.338
Authors: T Yamamoto; R Sakakibara; T Uchiyama; C Yamaguchi; F Nomura; T Ito; M Yanagisawa; M Yano; Y Awa; T Yamanishi; T Hattori; S Kuwabara Journal: Neurourol Urodyn Date: 2010-07-23 Impact factor: 2.696
Authors: R Sakakibara; T Hattori; T Uchiyama; K Kita; M Asahina; A Suzuki; T Yamanishi Journal: J Neurol Neurosurg Psychiatry Date: 2000-01 Impact factor: 10.154
Authors: K Hirayama; T Takayanagi; R Nakamura; N Yanagisawa; T Hattori; K Kita; S Yanagimoto; M Fujita; M Nagaoka; Y Satomura Journal: Acta Neurol Scand Suppl Date: 1994
Authors: Elizabeth A Coon; David M Sletten; Mariana D Suarez; Jay N Mandrekar; J Eric Ahlskog; James H Bower; Joseph Y Matsumoto; Michael H Silber; Eduardo E Benarroch; Robert D Fealey; Paola Sandroni; Phillip A Low; Wolfgang Singer Journal: Brain Date: 2015-09-13 Impact factor: 13.501
Authors: S Gilman; G K Wenning; P A Low; D J Brooks; C J Mathias; J Q Trojanowski; N W Wood; C Colosimo; A Dürr; C J Fowler; H Kaufmann; T Klockgether; A Lees; W Poewe; N Quinn; T Revesz; D Robertson; P Sandroni; K Seppi; M Vidailhet Journal: Neurology Date: 2008-08-26 Impact factor: 9.910