Literature DB >> 28189272

Alice in Wonderland Syndrome: A real life version of Lewis Carroll's novel.

Patrick O'Toole1, Edward Justin Modestino2.   

Abstract

Alice in Wonderland Syndrome was originally coined by Dr. John Todd in 1955. The syndrome is named after the sensations experienced by the character Alice in Lewis Carroll's novel Alice's Adventures in Wonderland. Alice in Wonderland Syndrome consists of metamorphopsia (seeing something in a distorted fashion), bizarre distortions of their body image, and bizarre perceptual distortions of form, size, movement or color. Additionally, patients with Alice in Wonderland Syndrome can experience auditory hallucinations and changes in their perception of time. Currently, there is no known specific cause of Alice in Wonderland Syndrome. However, theories point to infections such as the Epstein-Barr virus, medications such as topiramate and associated migraines. Neuroimaging studies have revealed brain regions involved with the manifestation of symptoms. These include the temporo-parietal junction within the temporal lobe and the visual pathway, specifically the occipital lobe. There are no current treatments for Alice in Wonderland Syndrome. Further research is needed to find better treatments for Alice in Wonderland Syndrome and to elucidate the exact cause or causes of Alice in Wonderland Syndrome.
Copyright © 2017 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Alice in Wonderland Syndrome; Auditory hallucinations; Neuroimaging; Perceptual distortion; Visual hallucinations

Mesh:

Year:  2017        PMID: 28189272     DOI: 10.1016/j.braindev.2017.01.004

Source DB:  PubMed          Journal:  Brain Dev        ISSN: 0387-7604            Impact factor:   1.961


  6 in total

1.  A singular association of migraine with brainstem aura and Alice in Wonderland syndrome.

Authors:  Domenico Chirchiglia; Pasquale Chirchiglia; Rosa Marotta
Journal:  Childs Nerv Syst       Date:  2019-05-02       Impact factor: 1.475

2.  Functional connectivity alterations in migraineurs with Alice in Wonderland syndrome.

Authors:  Claudia Piervincenzi; Nikolaos Petsas; Alessandro Viganò; Valentina Mancini; Giulio Mastria; Marta Puma; Costanza Giannì; Vittorio Di Piero; Patrizia Pantano
Journal:  Neurol Sci       Date:  2022-09-17       Impact factor: 3.830

3.  Alice in Wonderland syndrome: a lesion mapping study.

Authors:  Claudia Piervincenzi; Nikolaos Petsas; Costanza Giannì; Vittorio Di Piero; Patrizia Pantano
Journal:  Neurol Sci       Date:  2021-12-02       Impact factor: 3.830

4.  Clinical characteristics of Alice in Wonderland syndrome in a cohort with vestibular migraine.

Authors:  Shin C Beh; Shamin Masrour; Stacy V Smith; Deborah I Friedman
Journal:  Neurol Clin Pract       Date:  2018-10

Review 5.  Alice in Wonderland syndrome (AIWS): a research overview.

Authors:  Md Mahbub Hossain
Journal:  AIMS Neurosci       Date:  2020-10-19

6.  Alice in Wonderland syndrome: a novel neurological presentation of Zika virus infection.

Authors:  Alberto E Paniz-Mondolfi; José Giraldo; Alfonso J Rodríguez-Morales; Oriana Pacheco; Germán Y Lombó-Lucero; Juan D Plaza; Fabio J Adami-Teppa; Alejandra Carrillo; Carlos E Hernandez-Pereira; Gabriela M Blohm
Journal:  J Neurovirol       Date:  2018-08-13       Impact factor: 3.739

  6 in total

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