Literature DB >> 28188210

Management of oral secretions in neurological disease.

Alexander J McGeachan1, Christopher J Mcdermott2.   

Abstract

Sialorrhoea is a common and problematic symptom that arises from a range of neurological conditions associated with bulbar or facial muscle dysfunction. Drooling can significantly affect quality of life due to both physical complications such as oral chapping, and psychological complications such as embarrassment and social isolation. Thicker, tenacious oral and pharyngeal secretions may result from the drying management approach to sialorrhoea. The management of sialorrhoea in neurological diseases depends on the underlying pathology and severity of symptoms. Interventions include anticholinergic drugs, salivary gland-targeted radiotherapy, salivary gland botulinum toxin and surgical approaches. The management of thick secretions involves mainly conservative measures such as pineapple juice as a lytic agent, cough assist, saline nebulisers and suctioning or mucolytic drugs like carbocisteine. Despite a current lack of evidence and variable practice, management of sialorrhoea should form a part of the multidisciplinary approach needed for long-term neurological conditions. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Mesh:

Substances:

Year:  2017        PMID: 28188210     DOI: 10.1136/practneurol-2016-001515

Source DB:  PubMed          Journal:  Pract Neurol        ISSN: 1474-7758


  12 in total

1.  IncobotulinumtoxinA for hypersalivation in patients with amyotrophic lateral sclerosis: an open-label single-centre study.

Authors:  Lejla Paracka; Katja Kollewe; Martin Klietz; Susanne Petri; Dirk Dressler
Journal:  J Neural Transm (Vienna)       Date:  2019-07-17       Impact factor: 3.575

2.  Localization of Salivary Glands for Botulinum Toxin Treatment: Ultrasound Versus Landmark Guidance.

Authors:  Sebastian Loens; Norbert Brüggemann; Armin Steffen; Tobias Bäumer
Journal:  Mov Disord Clin Pract       Date:  2019-12-30

Review 3.  Gastrointestinal Dysfunction in Parkinson's Disease.

Authors:  Delaram Safarpour; Kaveh Sharzehi; Ronald F Pfeiffer
Journal:  Drugs       Date:  2022-01-25       Impact factor: 9.546

4.  Impact and management of drooling in children with neurological disorders: an Italian Delphi consensus.

Authors:  Antonella Riva; Elisabetta Amadori; Maria Stella Vari; Alberto Spalice; Vincenzo Belcastro; Maurizio Viri; Donatella Capodiferro; Antonino Romeo; Alberto Verrotti; Pasquale Striano
Journal:  Ital J Pediatr       Date:  2022-07-19       Impact factor: 3.288

5.  SIAXI: Placebo-controlled, randomized, double-blind study of incobotulinumtoxinA for sialorrhea.

Authors:  Wolfgang H Jost; Andrzej Friedman; Olaf Michel; Christian Oehlwein; Jaroslaw Slawek; Andrzej Bogucki; Stanislaw Ochudlo; Marta Banach; Fernando Pagan; Birgit Flatau-Baqué; János Csikós; Claire J Cairney; Andrew Blitzer
Journal:  Neurology       Date:  2019-03-27       Impact factor: 9.910

6.  Safety and Efficacy of RimabotulinumtoxinB for Treatment of Sialorrhea in Adults: A Randomized Clinical Trial.

Authors:  Stuart H Isaacson; William Ondo; Carlayne E Jackson; Richard M Trosch; Eric Molho; Fernando Pagan; Mark Lew; Khashayar Dashtipour; Thomas Clinch; Alberto J Espay
Journal:  JAMA Neurol       Date:  2020-04-01       Impact factor: 18.302

7.  Efficacy of scopolamine transdermal patch in children with sialorrhea in a pediatric tertiary care hospital.

Authors:  Majed Al Jeraisy; Maissa AlFuraih; Raghad AlSaif; Bushra AlKhalifah; Hazza AlOtaibi; Mostafa A Abolfotouh
Journal:  BMC Pediatr       Date:  2020-09-17       Impact factor: 2.125

8.  Botulinum Toxin A for Sialorrhoea Associated with Neurological Disorders: Evaluation of the Relationship between Effect of Treatment and the Number of Glands Treated.

Authors:  Domenico A Restivo; Mariangela Panebianco; Antonino Casabona; Sara Lanza; Rosario Marchese-Ragona; Francesco Patti; Stefano Masiero; Antonio Biondi; Angelo Quartarone
Journal:  Toxins (Basel)       Date:  2018-01-27       Impact factor: 4.546

Review 9.  Therapy of Sialorrhea with Botulinum Neurotoxin.

Authors:  Wolfgang H Jost; Tobias Bäumer; Rainer Laskawi; Jaroslaw Slawek; Björn Spittau; Armin Steffen; Martin Winterholler; Ganesh Bavikatte
Journal:  Neurol Ther       Date:  2019-09-21

Review 10.  Sialorrhea in Parkinson's Disease.

Authors:  Jonathan Isaacson; Sanskruti Patel; Yasar Torres-Yaghi; Fernando Pagán
Journal:  Toxins (Basel)       Date:  2020-10-31       Impact factor: 4.546

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.