Literature DB >> 28187280

Cancer Clinical Trials: The Rear-View Mirror and the Crystal Ball.

Dave Cescon1, Lillian L Siu2.   

Abstract

Clinical trials are key to translating scientific advances into progress in cancer research and care. Confronted by developments in basic science, the landscape of clinical cancer research is rapidly evolving. Here, we review recent changes in clinical trials' design and conduct, and we forecast future directions toward personalized and global impact.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28187280     DOI： 10.1016/j.cell.2017.01.027

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  7 in total

Review 1.  Circulating tumor DNA and liquid biopsy in oncology.

Authors:  David W Cescon; Scott V Bratman; Steven M Chan; Lillian L Siu
Journal:  Nat Cancer       Date:  2020-03-20

Review 2.  Targeting the cell cycle in breast cancer: towards the next phase.

Authors:  K L Thu; I Soria-Bretones; T W Mak; D W Cescon
Journal:  Cell Cycle       Date:  2018-09-11       Impact factor: 4.534

Review 3.  The Emerging Potential for Network Analysis to Inform Precision Cancer Medicine.

Authors:  Kivilcim Ozturk; Michelle Dow; Daniel E Carlin; Rafael Bejar; Hannah Carter
Journal:  J Mol Biol       Date:  2018-06-15       Impact factor: 5.469

4.  Disruption of the anaphase-promoting complex confers resistance to TTK inhibitors in triple-negative breast cancer.

Authors:  K L Thu; J Silvester; M J Elliott; W Ba-Alawi; M H Duncan; A C Elia; A S Mer; P Smirnov; Z Safikhani; B Haibe-Kains; T W Mak; D W Cescon
Journal:  Proc Natl Acad Sci U S A       Date:  2018-01-29       Impact factor: 11.205

Review 5.  Innovative highlights of clinical drug trial design.

Authors:  Daohong Chen; Eric Yining Qi
Journal:  Transl Res       Date:  2020-06-03       Impact factor: 7.012

6.  Gene Expression Analyses in Breast Cancer: Sample Matters.

Authors:  Benjamin Haibe-Kains; David W Cescon
Journal:  JNCI Cancer Spectr       Date:  2018-05-22

Review 7.  Patient-derived cancer models: Valuable platforms for anticancer drug testing.

Authors:  Sofia Genta; Bryan Coburn; David W Cescon; Anna Spreafico
Journal:  Front Oncol       Date:  2022-08-12       Impact factor: 5.738
  7 in total

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