Literature DB >> 28185322

A Difunctional Regeneration Scaffold for Knee Repair based on Aptamer-Directed Cell Recruitment.

Xiaoxia Hu1, Yulan Wang2,3, Yaning Tan1, Jie Wang1, Haoyang Liu1, Yingqian Wang1, Shuang Yang2, Miusi Shi2, Shiyong Zhao2, Yufeng Zhang2,3, Quan Yuan1.   

Abstract

To solve the challenge of poor knee repair, an aptamer-bilayer scaffold is designed for autologous mesenchymal stem cell (MSC) recruitment and osteochondral regeneration. The scaffold can efficiently recruit MSCs to the defect and induce the directional differentiation of MSCs, thus successfully achieving simultaneous regeneration of cartilage and bone in the knee joint.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  aptamers; cell recruitment; knee repair; osteochondral defect; scaffolds

Mesh：

Year:  2017        PMID： 28185322     DOI： 10.1002/adma.201605235

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  22 in total

1.  Zero-Dimensional Carbon Dots Enhance Bone Regeneration, Osteosarcoma Ablation, and Clinical Bacterial Eradication.

Authors:  Yao Lu; Lihua Li; Mei Li; Zefeng Lin; Liping Wang; Yu Zhang; Qingshui Yin; Hong Xia; Gang Han
Journal:  Bioconjug Chem       Date:  2018-08-07       Impact factor: 4.774

2.  Carbon nanotube-mediated antibody-free suspension array for determination of typical endocrine-disrupting chemicals.

Authors:  Nan Liu; Jing Wu; Yunlei Xianyu; Weijie Liang; Ya Li; Lugang Deng; Yiping Chen
Journal:  Mikrochim Acta       Date:  2020-03-06       Impact factor: 5.833

Review 3.  Aptamer-functionalized hydrogels: An emerging class of biomaterials for protein delivery, cell capture, regenerative medicine, and molecular biosensing.

Authors:  Lidya Abune; Brandon Davis; Yong Wang
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2021-06-15

4.  Hybridizing gellan/alginate and thixotropic magnesium phosphate-based hydrogel scaffolds for enhanced osteochondral repair.

Authors:  You Chen; Yuanyuan Chen; Xiong Xiong; Rongwei Cui; Guowei Zhang; Chen Wang; Dongqin Xiao; Shuxin Qu; Jie Weng
Journal:  Mater Today Bio       Date:  2022-04-13

Review 5.  Contributions of Bioactive Molecules in Stem Cell-Based Periodontal Regeneration.

Authors:  An-Qi Liu; Cheng-Hu Hu; Fang Jin; Li-Shu Zhang; Kun Xuan
Journal:  Int J Mol Sci       Date:  2018-03-28       Impact factor: 5.923

6.  An Aptamer-Based Probe for Molecular Subtyping of Breast Cancer.

Authors:  Mei Liu; Zhifei Wang; Ting Tan; Zhongsi Chen; Xianbo Mou; Xiaocheng Yu; Yan Deng; Guangming Lu; Nongyue He
Journal:  Theranostics       Date:  2018-11-10       Impact factor: 11.556

Review 7.  Material-Assisted Strategies for Osteochondral Defect Repair.

Authors:  Constance Lesage; Marianne Lafont; Pierre Guihard; Pierre Weiss; Jérôme Guicheux; Vianney Delplace
Journal:  Adv Sci (Weinh)       Date:  2022-03-24       Impact factor: 17.521

8.  Bi-layered Composite Scaffold for Repair of the Osteochondral Defects.

Authors:  Dongdong Xu; Gu Cheng; Jinhong Dai; Zhi Li
Journal:  Adv Wound Care (New Rochelle)       Date:  2020-12-18       Impact factor: 4.947

Review 9.  Biochemical Stimulus-Based Strategies for Meniscus Tissue Engineering and Regeneration.

Authors:  Mingxue Chen; Weimin Guo; Shunag Gao; Chunxiang Hao; Shi Shen; Zengzeng Zhang; Zhenyong Wang; Zehao Wang; Xu Li; Xiaoguang Jing; Xueliang Zhang; Zhiguo Yuan; Mingjie Wang; Yu Zhang; Jiang Peng; Aiyuan Wang; Yu Wang; Xiang Sui; Shuyun Liu; Quanyi Guo
Journal:  Biomed Res Int       Date:  2018-01-17       Impact factor: 3.411

10.  Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface.

Authors:  Cuijun Deng; Huiying Zhu; Jiayi Li; Chun Feng; Qingqiang Yao; Liming Wang; Jiang Chang; Chengtie Wu
Journal:  Theranostics       Date:  2018-02-15       Impact factor: 11.556
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