Literature DB >> 28185289

Effect of epidural compared to patient-controlled intravenous analgesia on outcomes for patients undergoing liver resection for neoplastic disease.

Shelby Allen1, Amy DeRoche2, Lu Adams2, Karen Valerie Slocum2, Clancy J Clark3, Nora F Fino4, Perry Shen3.   

Abstract

BACKGROUND: Epidural analgesia is routinely used for postoperative pain control following abdominal surgeries, yet data regarding the safety and efficacy of epidural analgesia is controversial.
METHODS: Pain-related and clinical perioperative data were extracted and correlated with baseline clinicopathologic data and method of analgesia (epidural vs. intravenous patient-controlled analgesia) in patients who underwent hepatectomy from 2012 to 2014. Chronic pain was defined by specific narcotic requirements preoperatively.
RESULTS: Eighty-seven patients underwent hepatectomy with 60% having epidurals placed for postoperative pain control. Epidural patients underwent more major hepatectomies and open resections. Comparison of pain scores between both groups demonstrated no significant difference (all P > .05). A significantly lower proportion of TEA patients required additional IV pain medications than those with IVPCA (P < 0.001). There was no major effect of epidural analgesia on time to ambulation or complications (all P > 0.05). After adjusting for perioperative factors, and surgical extent and approach, no significant differences in fluids administered or length of stay were detected.
CONCLUSIONS: Overall postoperative outcomes were not significantly different based on method of analgesia after adjusting for type and extent of hepatic resection. Though patients with epidurals underwent more extensive operations they required less additional IV pain medications than IVPCA patients.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  analgesia; epidural; hepatectomy

Mesh:

Substances:

Year:  2017        PMID: 28185289      PMCID: PMC5400729          DOI: 10.1002/jso.24534

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  16 in total

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2.  Coagulation profile changes and safety of epidural analgesia after hepatectomy: a retrospective study.

Authors:  Kelly G Elterman; Zhiling Xiong
Journal:  J Anesth       Date:  2014-11-13       Impact factor: 2.078

Review 3.  Impact of epidural analgesia on mortality and morbidity after surgery: systematic review and meta-analysis of randomized controlled trials.

Authors:  Daniel M Pöpping; Nadia Elia; Hugo K Van Aken; Emmanuel Marret; Stephan A Schug; Peter Kranke; Manuel Wenk; Martin R Tramèr
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Review 4.  Enhanced recovery after surgery protocols for open hepatectomy--physiology, immunomodulation, and implementation.

Authors:  Andrew J Page; Aslam Ejaz; Gaya Spolverato; Tiffany Zavadsky; Michael C Grant; Daniel J Galante; Elizabeth C Wick; Matthew Weiss; Martin A Makary; Christopher L Wu; Timothy M Pawlik
Journal:  J Gastrointest Surg       Date:  2014-12-04       Impact factor: 3.452

5.  Risk factors for coagulopathy after liver resection.

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  8 in total

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4.  The Opioid-Sparing Effect of Perioperative Dexmedetomidine Combined with Oxycodone Infusion during Open Hepatectomy: A Randomized Controlled Trial.

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Journal:  Front Pharmacol       Date:  2018-01-04       Impact factor: 5.810

5.  Efficacy of oxycodone in intravenous patient-controlled analgesia with different infusion modes after laparoscopic radical surgery of cervical cancer a prospective, randomized, double-blind study.

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6.  Epidural and Non-epidural Analgesia in Patients Undergoing Open Pancreatectomy: a Retrospective Cohort Study.

Authors:  Jesse V Groen; David E F Slotboom; Jaap Vuyk; Chris H Martini; Albert Dahan; Alexander L Vahrmeijer; Bert A Bonsing; J Sven D Mieog
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7.  Regional analgesia modalities in abdominal and lower limb surgery - comparison of efficacy.

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  8 in total

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