Merih Oray1, Sumru Önal2, Aylin Koç Akbay3, İlknur Tuğal Tutkun1. 1. İstanbul University İstanbul Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey. 2. Koç University Faculty of Medicine, Department of Ophthalmology; VKV American Hospital, Ophthalmology Clinic, İstanbul, Turkey. 3. Koç University Faculty of Medicine, Department of Ophthalmology, İstanbul, Turkey.
Abstract
OBJECTIVES: To describe ocular manifestations, diagnosis, and treatment of cat scratch disease. MATERIALS AND METHODS: Clinical records of patients with ocular cat scratch disease were reviewed. RESULTS: Thirteen eyes of 10 patients (7 female, 3 male) with a mean age of 26.9±18.5 years were included. Nine patients had a history of cat contact and had systemic symptoms associated with cat scratch disease 2-90 days prior to the ocular symptoms. Ocular signs were: neuroretinitis in 4 eyes (associated with serous retinal detachment in the inferior quadrant in 1 eye), optic neuropathy in 2 eyes (1 papillitis and optic disc infiltration, 1 optic neuritis), retinal infiltrates in 6 eyes, retinochoroiditis in 1 eye, branch retinal arteriolar occlusion in 3 eyes, and endophthalmitis in 1 eye. Visual acuities at presentation were 1.0 in 7 eyes, 0.3 in 1 eye, ≤0.1 in 4 eyes, and light perception in 1 eye. Bartonella henselae immunoglobulin (Ig) M and/or IgG were positive in all patients. Systemic antibiotic therapy was administered in all patients. Systemic corticosteroid treatment (15-40 mg/day) was added to the therapy in 4 patients, following 5 days of intravenous pulse methylprednisolone in 2 patients. Treatment was ongoing for 1 patient and the mean treatment duration of the other 9 patients was 47±14.5 days. Visual acuities at final visit were 1.0 in 9 eyes, 0.8 in 1 eye, 0.4 in 1 eye, and no light perception in 1 eye. CONCLUSION: Cat scratch disease may present with different ocular signs and should be considered in the differential diagnosis in patients with such presentations.
OBJECTIVES: To describe ocular manifestations, diagnosis, and treatment of cat scratch disease. MATERIALS AND METHODS: Clinical records of patients with ocular cat scratch disease were reviewed. RESULTS: Thirteen eyes of 10 patients (7 female, 3 male) with a mean age of 26.9±18.5 years were included. Nine patients had a history of cat contact and had systemic symptoms associated with cat scratch disease 2-90 days prior to the ocular symptoms. Ocular signs were: neuroretinitis in 4 eyes (associated with serous retinal detachment in the inferior quadrant in 1 eye), optic neuropathy in 2 eyes (1 papillitis and optic disc infiltration, 1 optic neuritis), retinal infiltrates in 6 eyes, retinochoroiditis in 1 eye, branch retinal arteriolar occlusion in 3 eyes, and endophthalmitis in 1 eye. Visual acuities at presentation were 1.0 in 7 eyes, 0.3 in 1 eye, ≤0.1 in 4 eyes, and light perception in 1 eye. Bartonella henselae immunoglobulin (Ig) M and/or IgG were positive in all patients. Systemic antibiotic therapy was administered in all patients. Systemic corticosteroid treatment (15-40 mg/day) was added to the therapy in 4 patients, following 5 days of intravenous pulse methylprednisolone in 2 patients. Treatment was ongoing for 1 patient and the mean treatment duration of the other 9 patients was 47±14.5 days. Visual acuities at final visit were 1.0 in 9 eyes, 0.8 in 1 eye, 0.4 in 1 eye, and no light perception in 1 eye. CONCLUSION: Cat scratch disease may present with different ocular signs and should be considered in the differential diagnosis in patients with such presentations.
Authors: J E Koehler; M A Sanchez; C S Garrido; M J Whitfeld; F M Chen; T G Berger; M C Rodriguez-Barradas; P E LeBoit; J W Tappero Journal: N Engl J Med Date: 1997-12-25 Impact factor: 91.245
Authors: K M Zangwill; D H Hamilton; B A Perkins; R L Regnery; B D Plikaytis; J L Hadler; M L Cartter; J D Wenger Journal: N Engl J Med Date: 1993-07-01 Impact factor: 91.245
Authors: Dimitrios Kalogeropoulos; Ioannis Asproudis; Maria Stefaniotou; Marilita M Moschos; Andreas Mentis; Konstantinos Malamos; Chris Kalogeropoulos Journal: Int Ophthalmol Date: 2019-03-09 Impact factor: 2.031
Authors: B Canneti; I Cabo-López; A Puy-Núñez; J C García García; F J Cores; M Trigo; A P Suárez-Gil; A Rodriguez-Regal Journal: Neurol Sci Date: 2018-10-27 Impact factor: 3.307
Authors: Walter de Araujo Eyer-Silva; Letícia Stéfanie Curvello Wutke; Alexandre de Carvalho Mendes Paiva; Guilherme Almeida Rosa da Silva; Fernando Raphael de Almeida Ferry; Dario José Hart Pontes Signorini; Jonathan Gonçalves de Oliveira; Elba Regina Sampaio Lemos Journal: Rev Soc Bras Med Trop Date: 2020-06-22 Impact factor: 1.581