Literature DB >> 28181550

Corrigendum: Long intergenic non-coding RNA 271 is predictive of a poorer prognosis of papillary thyroid cancer.

Ben Ma, Tian Liao, Duo Wen, Chuanpeng Dong, Li Zhou, Shuwen Yang, Yu Wang, Qinghai Ji.   

Abstract

Entities:  

Year:  2017        PMID: 28181550      PMCID: PMC5299956          DOI: 10.1038/srep42321

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


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This Article contains errors in Table 1 and Table 4. The correct Table 1 and Table 4 appear below as Table 1 and Table 2 respectively.
Table 1

Clinicopathological characteristics of PTC patients in the FUSCC and TCGA cohorts.

VariablesTCGA (N = 471)
FUSCC (N = 185)
P value
N%N%
Age (years)    0.099
 <4521746.19953.5 
 ≥4525453.98646.5 
Gender    0.374
 Male12626.84323.2 
 Female34573.214276.8 
Multifocality    <0.001
 Unifocal25054.213573.0 
 Multifocal21145.85027.0 
Histological type    <0.001
 Classical PTC32970.918398.9 
 Follicular PTC9921.321.1 
 Tall-cell PTC367.800 
Coexistent HT    0.004
 Yes6614.04423.8 
 No40586.014176.2 
ETE    <0.001
 No31366.516890.8 
 Yes14430.6179.2 
 NA143.000 
T Stage    <0.001
 T1-T228259.916689.7 
 T3-T418839.91910.3 
 NA10.200 
LNM    <0.001
 N021545.68545.9 
 N121044.610054.1 
 NA469.800 
M    <0.001
 M026355.8185100 
 M181.700 
 NA20042.500 
TNM Stage    <0.001
 I-II31266.215282.1 
 III-IV15733.33317.9 
 NA20.400 
BRAFV600E    <0.001
 Mutation22247.110355.7 
 Wild-type17737.67942.7 
 NA7215.331.6 

Notes: Italic and bold type indicates statistical significance. Abbreviations: PTC, papillary thyroid cancer; FUSCC, Fudan University Shanghai Cancer Center; TCGA, The Cancer Genomics Atlas; HT, Hashimoto’s thyroiditis; ETE, extrathyroidal extension; LNM, lymph node metastasis; M, metastasis; TNM, tumor-node-metastasis.

Table 2

Cox proportional hazards analysis of factors associated with RFS for PTC patients in TCGA cohort.

VariablesUnivariate analysisMultivariate analysis
P valueaHR95.0% CI for HRP valueaHR95.0% CI for HR
Ageb0.1951.0160.992–1.0400.9771.0000.968–1.034
Genderb
 Male 1  1 
 Female0.0090.3500.159–0.7690.0210.3860.172–0.868
Multifocality
 Unifocal 1    
 Multifocal0.1061.9330.868–4.300   
Histological subtypesb
 Classical PTC 1  1 
 Follicular PTC0.9130.9410.318–2.7860.8711.0950.367–3.269
 Tall-cell PTC0.2022.2290.650–7.6410.8861.0980.306–3.949
Coexistent HT
 No 1    
 Yes0.7401.7290.648–4.616   
ETE
 No 1    
 Yes0.1821.7120.777–3.773   
T stageb
 T1-T2 1  1 
 T3-T40.0472.2941.010–5.2110.5081.4010.516–3.806
LNM
 No 1    
 Yes0.1112.0770.846–5.100   
TNM stageb
 Stage I-II 1  1 
 Stage III-IV0.0522.1760.992–4.7730.6641.3260.371–4.738
BRAFV600E
 Wild-type 1    
 Mutation0.3651.5570.597–4.057   
LINC00271b
 ≥cutoff 1  1 
 <cutoffc0.0093.6881.384–9.8290.0253.1821.160–8.726

Notes: aItalic and bold type indicates statistical significance; badjusted by age, gender, histological subtypes, T stage, TNM stage and LINC00271 in multivariate analysis; c, LINC00271 expression level less than the best cutoff value for prediction of recurrence; Abbreviations: PTC, papillary thyroid cancer; TCGA, The Cancer Genomics Atlas; OR, odds ratio; CI, confidence interval; HT, Hashimoto’s thyroiditis; ETE, extrathyroidal extension; LNM, lymph node metastasis; TNM, tumor-node-metastasis.

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1.  Noncoding RNAs in Papillary Thyroid Cancer: Interaction with Cancer-Associated Fibroblasts (CAFs) in the Tumor Microenvironment (TME) and Regulators of Differentiation and Lymph Node Metastasis.

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2.  Overexpression of novel long intergenic non‑coding RNA LINC02454 is associated with a poor prognosis in papillary thyroid cancer.

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3.  MEG3 Expression Indicates Lymph Node Metastasis and Presence of Cancer-Associated Fibroblasts in Papillary Thyroid Cancer.

Authors:  Sina Dadafarin; Tomás C Rodríguez; Michelle A Carnazza; Raj K Tiwari; Augustine Moscatello; Jan Geliebter
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