Vito Cantisani1, Emanuele David2, Armando De Virgilio3, Paul S Sidhu4, Hektor Grazhdani5, Antonio Greco3, Marco De Vincentiis3, Alessandro Corsi6, Flaminia De Cristofaro7, Luca Brunese8, Fabrizio Calliada9, Alfredo Blandino2, Mario Tombolini3, Giorgio Ascenti2, Roberto Stramare10, Marcello Caratozzolo7, Ferdinando D'Ambrosio7. 1. Department of Radiology, Oncology, and Anatomy Pathology, Policlinico Umberto I, University Sapienza, Rome, Italy. vito.cantisani@uniroma1.it. 2. Department of Biomedical Sciences and Morphological and Functional Imaging, University of Messina, Policlinico "G. Martino", Messina, Italy. 3. Department of Sensory Organs, ENT Section, "Sapienza" University of Rome, Rome, Italy. 4. Department of Radiology, King's College Hospital, Denmark Hill, London, UK. 5. Associazione dei Cavalieri Italiani Sovrano Militare Ordine di Malta; Poliambulatorio Roma Eur, Rome, Italy. 6. Department of Molecular Medicine, Policlinico Umberto I, University Sapienza, Rome, Italy. 7. Department of Radiology, Oncology, and Anatomy Pathology, Policlinico Umberto I, University Sapienza, Rome, Italy. 8. Department of Medicine and Health Sciences, University of Molise, Campobasso,Italy. 9. University Hospital of Pavia, Pavia, Italy. 10. University of Padova , Department of Medicine, Padova, Italy.
Abstract
AIMS: To assess the diagnostic value of elasticity contrast index (ECI) elastography, in comparison with conventional ultrasound for the differentiation of benign and malignant parotid lesions. MATERIAL AND METHODS: Sixty-three consecutive patients with parotid gland tumors, treated surgically at a single tertiary center were enrolled. Ultrasound evaluation consisted of B-mode, color-Doppler and quasistatic ultrasound elastography (USE), conducted with the ECI technique. For each lesion the echogenicity, margins, vascularization, and capsulation were considered to determine benign or malignant lesions. Histology was considered the gold standard. RESULTS: Using conventional parameters, the observer suggested malignant lesions in 20 cases and benign lesions in 43 cases (accuracy: 61.8%). ECI>3.5 alone was the most accurate parameter (accuracy: 90.5%), with sensitivity of 93.7% and specificity of 89.4%. However, when combined with the other US criteria, no statistically significant diagnostic accuracy improvement was achieved. CONCLUSIONS: Our results show that USE with ECI index measurement can help to discriminate preoperatively benign from malignant lesions, with the exception of pleomorphic adenoma which is stiff. We suggest that USE can be used as an additional tool to conventional US evaluation of salivary gland lesions.
AIMS: To assess the diagnostic value of elasticity contrast index (ECI) elastography, in comparison with conventional ultrasound for the differentiation of benign and malignant parotid lesions. MATERIAL AND METHODS: Sixty-three consecutive patients with parotid gland tumors, treated surgically at a single tertiary center were enrolled. Ultrasound evaluation consisted of B-mode, color-Doppler and quasistatic ultrasound elastography (USE), conducted with the ECI technique. For each lesion the echogenicity, margins, vascularization, and capsulation were considered to determine benign or malignant lesions. Histology was considered the gold standard. RESULTS: Using conventional parameters, the observer suggested malignant lesions in 20 cases and benign lesions in 43 cases (accuracy: 61.8%). ECI>3.5 alone was the most accurate parameter (accuracy: 90.5%), with sensitivity of 93.7% and specificity of 89.4%. However, when combined with the other US criteria, no statistically significant diagnostic accuracy improvement was achieved. CONCLUSIONS: Our results show that USE with ECI index measurement can help to discriminate preoperatively benign from malignant lesions, with the exception of pleomorphic adenoma which is stiff. We suggest that USE can be used as an additional tool to conventional US evaluation of salivary gland lesions.
Authors: Vivian Thimsen; Miguel Goncalves; Michael Koch; Konstantinos Mantsopoulos; Joachim Hornung; Heinrich Iro; Mirco Schapher Journal: Gland Surg Date: 2021-04