Literature DB >> 2817964

Successful pregnancy in a patient with paroxysmal nocturnal hemoglobinuria: case report.

A Imai1, H Takagi, I Kawabata, H Sumi, S Shiraki, T Tamaya.   

Abstract

In this report, the maternal and fetal risks in a patient with paroxysmal nocturnal hemoglobinuria (PNH) were evaluated. A patient with PNH carried a pregnancy to successful delivery, with a healthy male infant, and suffered from postpartum cerebral subcortical thrombosis followed by recovery. An elevated level of serum lactate dehydrogenase isoenzyme (alpha-hydroxybutyrate dehydrogenase) was observed during pregnancy; the level returned to normal by delivery. However, the hemoglobin concentration during pregnancy and post-partum was kept at 8 g/dl. This is the first report of a relation between the onset of hemolysis and pregnancy. The management of pregnancy in such patients is discussed.

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Year:  1989        PMID： 2817964     DOI： 10.1007/BF00934129

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN： 0932-0067            Impact factor:   2.344


  10 in total

Review 1.  Paroxysmal nocturnal haemoglobinuria.

Authors:  G Sirchia; S M Lewis
Journal:  Clin Haematol       Date:  1975-02

2.  Paroxysmal nocturnal hemoglobinuria: relation of the clinical manifestations to underlying pathogenic mechanisms.

Authors:  W H CROSBY
Journal:  Blood       Date:  1953-09       Impact factor: 22.113

3.  Paroxysmal nocturnal haemoglobinuria parturition complicated by presumed hepatic vein thrombosis.

Authors:  P R Payne; J M Holt; P B Neame
Journal:  J Obstet Gynaecol Br Commonw       Date:  1968-10

Review 4.  Pregnancy in a patient with paroxysmal nocturnal hemoglobinuria.

Authors:  J T Frakes; R E Burmeister; J J Giliberti
Journal:  Obstet Gynecol       Date:  1976-01       Impact factor: 7.661

5.  Pregnancy and paroxysmal nocturnal hemoglobinuria: report of a case and review of the literature.

Authors:  M F Greene; F D Frigoletto; S Claster; D Rosenthal
Journal:  Obstet Gynecol Surv       Date:  1983-10       Impact factor: 2.347

Review 6.  Paroxysmal nocturnal hemoglobinuria: recent advance in the clinical and laboratory studies on the Japanese patients.

Authors:  S Fujioka
Journal:  Nihon Ketsueki Gakkai Zasshi       Date:  1985-12

7.  Prospective hemostatic studies in a patient having paroxysmal nocturnal hemoglobinuria, pregnancy, and cerebral venous thrombosis.

Authors:  A J Wozniak; C S Kitchens
Journal:  Am J Obstet Gynecol       Date:  1982-03-01       Impact factor: 8.661

8.  Pregnancy associated with paroxysmal nocturnal hemoglobinuria.

Authors:  W W Hurd; M Miodovnik; S J Stys
Journal:  Obstet Gynecol       Date:  1982-12       Impact factor: 7.661

9.  Cerebral vein thrombosis and the contraceptive pill in paroxysmal nocturnal haemoglobinuria.

Authors:  M L Stirling; R J Lenton; M D Sumerling
Journal:  Scott Med J       Date:  1980-07       Impact factor: 0.729

10.  Paroxysmal nocturnal haemoglobinuria in pregnancy: case report.

Authors:  J A Spencer
Journal:  Br J Obstet Gynaecol       Date:  1980-03
  10 in total
  2 in total

1.  Paroxysmal nocturnal hemoglobinuria and pregnancy before the eculizumab era: the French experience.

Authors:  Sophie de Guibert; Régis Peffault de Latour; Nathalie Varoqueaux; Hélène Labussière; Bernard Rio; Dominique Jaulmes; Jean-Richard Eveillard; Stéphanie Dulucq; Anne-Marie Stoppa; Didier Bouscary; François Girodon; Bernard Bonnotte; Djamila Laskri; Gérard Socié; Thierry Lamy
Journal:  Haematologica       Date:  2011-05-23       Impact factor: 9.941

Review 2.  Successful anticoagulant therapy for two pregnant PNH patients, and prospects for the eculizumab era.

Authors:  Yasuyoshi Morita; Jun-ichi Nishimura; Takahiro Shimada; Hirokazu Tanaka; Kentaro Serizawa; Yasuhiro Taniguchi; Mitsuhiro Tsuritani; Yuzuru Kanakura; Itaru Matsumura
Journal:  Int J Hematol       Date:  2013-03-02       Impact factor: 2.490
  2 in total

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