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Literature DB >> 28179145

Bringing new dimensions to drug discovery screening: impact of cellular stimulation technologies.

Elena Molokanova¹, Mark Mercola², Alex Savchenko³.

Abstract

The current mandate for the drug discovery industry is to develop more efficient drugs faster while reducing the costs associated with their development. Incorporation of cell stimulation technologies during screening assays is expected to revolutionize the discovery of novel drugs as well as safety pharmacology. In this review, we highlight 'classical' and emerging cell stimulation technologies that provide the ability to evaluate the effects of drug candidates on cells in different functional states to assess clinically relevant phenotypes.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Year: 2017 PMID： 28179145 PMCID： PMC5487284 DOI： 10.1016/j.drudis.2017.01.015

Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851

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